Statistik Asas
Pengurus Samuel Isaly
Profil Orang Dalam ORBIMED ADVISORS LLC
Nilai Portfolio $ 4,004,110,774
Kedudukan Semasa 102
Pegangan Terkini, Prestasi, AUM (dari 13F, 13D)

Orbimed Advisors Llc telah mendedahkan 102 jumlah pegangan dalam pemfailan SEC terkini mereka. Pengurus portfolio disenaraikan sebagai Samuel Isaly. Nilai portfolio terkini dikira sebagai $ 4,004,110,774 USD. Aset Sebenar Di Bawah Pengurusan (AUM) ialah nilai ini ditambah dengan tunai (yang tidak didedahkan). Pegangan teratas Orbimed Advisors Llc ialah Sinovac Biotech, Ltd. (US:SVA) , Boston Scientific Corporation (US:BSX) , Eli Lilly and Company (US:LLY) , Edgewise Therapeutics, Inc. (US:EWTX) , and Enliven Therapeutics, Inc. (US:ELVN) . Kedudukan baharu Orbimed Advisors Llc termasuk Caris Life Sciences, Inc. (US:CAI) , Roivant Sciences Ltd. (US:ROIV) , UnitedHealth Group Incorporated (US:UNH) , iTeos Therapeutics, Inc. (US:ITOS) , and UroGen Pharma Ltd. (US:URGN) . Industri teratas Orbimed Advisors Llc ialah "Insurance Agents, Brokers, And Service" (sic 64) , "Engineering, Accounting, Research, Management, And Related Services" (sic 87) , and "Health Services" (sic 80) .

Orbimed Advisors Llc - Nilai Portfolio
Tambah Dana Ini
ke Papan Pemuka anda
Kenaikan Teratas Suku Tahun Ini

Kami menggunakan perubahan dalam peruntukan portfolio kerana ini adalah metrik yang paling bermakna. Perubahan boleh disebabkan oleh perdagangan atau perubahan dalam harga saham.

Sekuriti Saham
(MM)		 Nilai
(MM$)		 Portfolio % ΔPortfolio %
3.03 81.09 2.0252 2.0252
8.29 144.63 3.6045 1.1187
2.78 31.32 0.7823 0.7823
2.81 302.17 7.5303 0.7647
5.69 62.52 1.5580 0.7273
1.71 133.58 3.3290 0.6819
3.70 64.28 1.6054 0.6815
0.59 100.25 2.4985 0.6544
0.47 81.84 2.0439 0.5529
0.34 111.49 2.7785 0.5505
Penurunan Teratas Suku Tahun Ini

Kami menggunakan perubahan dalam peruntukan portfolio kerana ini adalah metrik yang paling bermakna. Perubahan boleh disebabkan oleh perdagangan atau perubahan dalam harga saham.

Sekuriti Saham
(MM)		 Nilai
(MM$)		 Portfolio % ΔPortfolio %
15.52 203.45 5.0702 -2.8084
0.44 55.12 1.3737 -1.0907
0.05 18.85 0.4699 -1.0604
0.20 8.02 0.1998 -0.6008
1.08 35.58 0.8868 -0.5592
0.43 53.30 1.3282 -0.5357
0.00 0.00 -0.5276
0.00 0.00 -0.4115
2.61 29.12 0.7258 -0.2723
0.72 3.87 0.0965 -0.2354
Pemfailan 13D/G

Ini ialah senarai pemfailan 13D dan 13G yang dibuat pada tahun lepas (jika ada). Klik ikon pautan untuk melihat sejarah transaksi penuh. Baris hijau menunjukkan kedudukan baharu. Baris merah menunjukkan kedudukan tertutup.

Tarikh Fail Borang Sekuriti Saham
Terdahulu 		Saham
Semasa 		ΔSaham % % Pemilikan
 % ΔPemilikan
2025-09-02 13D STTK / Shattuck Labs, Inc. 6,306,127 9.99
2025-08-15 13D/A CMPX / Compass Therapeutics, Inc. 15,219,994 15,219,994 0.00 8.90 -19.09
2025-08-14 13G/A AVTX / Avalo Therapeutics, Inc. 967,000 967,000 0.00 8.90 -10.10
2025-08-14 13G/A NPCE / NeuroPace, Inc. 3,406,335 2,614,184 -23.26 8.00 -23.81
2025-08-14 13G CTMX / CytomX Therapeutics, Inc. 8,461,500 5.40
2025-08-14 13G/A VSTM / Verastem, Inc. 2,862,448 1,333,333 -53.42 2.40 -57.14
2025-08-14 13G/A / (98420X103) 134,947 1.70
2025-08-13 13D/A AVBP / ArriVent BioPharma, Inc. 3,027,328 3,027,328 0.00 7.50 -17.58
2025-07-30 13D/A IKNA / Ikena Oncology, Inc. 8,008,913 773,754 -90.34 6.92 -58.59
2025-07-24 13D/A PASG / Passage Bio, Inc. 243,878 132,473 -45.68 4.25 -45.65
2025-06-17 13D/A ELVN / Enliven Therapeutics, Inc. 7,918,163 7,918,163 0.00 13.40 -20.24
2025-05-15 13G/A CCCC / C4 Therapeutics, Inc. 2,925,900 4,655,600 59.12 6.60 57.14
2025-05-15 13G WHWK / Whitehawk Therapeutics, Inc. 4,166,000 8.90
2025-05-15 13G/A NSPR / InspireMD, Inc. 2,133,405 2,133,405 0.00 7.20 -13.25
2025-05-14 13D/A CRVS / Corvus Pharmaceuticals, Inc. 9,785,423 9,785,423 0.00 12.20 -11.59
2025-05-12 13D/A EWTX / Edgewise Therapeutics, Inc. 14,756,096 15,252,867 3.37 14.50 -7.05
2025-04-14 13D/A XTNT / Xtant Medical Holdings, Inc. 73,114,592 0 -100.00 0.00 -100.00
2025-03-12 13D/A IRON / Disc Medicine, Inc. 1,785,571 1,556,369 -12.84 4.50 -25.00
2025-02-14 13G/A CRBP / Corbus Pharmaceuticals Holdings, Inc. 589,200 718,200 21.89 5.90 20.41
2025-02-14 13G ADCT / ADC Therapeutics SA 3,437,813 3.60
2025-02-14 13G RAPT / RAPT Therapeutics, Inc. 13,135,260 9.90
2025-02-14 13G FBRX / Forte Biosciences, Inc. 0 510,000 8.00
2025-02-13 13D SION / Sionna Therapeutics, Inc.
2025-01-29 13D/A TRAW / Traws Pharma, Inc. 605,531 760,824 25.65 19.90 0.00
2024-11-14 13G/A ALXO / ALX Oncology Holdings Inc. 2,255,000 0 -100.00 0.00 -100.00
2024-11-14 13G/A SRRK / Scholar Rock Holding Corporation 2,960,000 503,400 -82.99 0.60 -85.37
2024-11-14 13G/A ELEV / Elevation Oncology, Inc. 3,000,000 2,441,275 -18.62 4.00 -41.18
2024-11-12 13D/A THRD / Third Harmonic Bio, Inc. 5,779,071 5,779,071 0.00 12.80 -10.49
2024-11-08 13D / (54173L101) 2,677,256 9.80
2024-10-25 13D/A TELA / TELA Bio, Inc. 2,124,267 1,182,717 -44.32 4.80 -44.19
2024-10-17 13D UPB / Upstream Bio, Inc. 4,554,873 8.90
2024-09-23 13D MBX / MBX Biosciences, Inc. 3,812,215 12.00
2024-09-16 13D/A TERN / Terns Pharmaceuticals, Inc. 7,562,971 7,562,971 0.00 9.00 -23.08
13F dan Pemfailan Dana

Borang ini telah difailkan pada 2025-08-14 untuk tempoh pelaporan 2025-06-30. Klik ikon pautan untuk melihat sejarah transaksi penuh.

Tingkatkan untuk membuka data premium dan eksport ke Excel .

28-07-2022: Nota Penting - Kami telah menukar layanan lajur Δ Portfolio % dalam jadual ini. Sebelum ini, kami melaporkannya sebagai peratus perubahan dalam peruntukan portfolio. Kini kami melaporkannya sebagai perubahan mentah dalam peruntukan portfolio (masih dilaporkan sebagai peratus). Dari segi formula, kami sebelum ini melaporkannya sebagai 100 * (peruntukan semasa - peruntukan terdahulu ) / peruntukan terdahulu. Kami kini melaporkannya sebagai (peruntukan semasa - peruntukan terdahulu).
Sekuriti Jenis Purata Harga Saham Saham
(MM)		 ΔSaham
(%)		 ΔSaham
(%)		 Nilai
($MM)		 Portfolio
(%)		 ΔPortfolio
(%)
SVA / Sinovac Biotech, Ltd. 2.72 0.00 334.00 0.00 8.3236 0.3612
BSX / Boston Scientific Corporation 2.81 0.00 302.17 6.47 7.5303 0.7647
LLY / Eli Lilly and Company 0.34 0.00 263.17 -5.62 6.5585 -0.0887
EWTX / Edgewise Therapeutics, Inc. 15.52 3.31 203.45 -38.44 5.0702 -2.8084
ELVN / Enliven Therapeutics, Inc. 7.96 0.00 159.67 1.93 3.9791 0.2448
ISRG / Intuitive Surgical, Inc. 0.29 0.00 158.13 9.72 3.9409 0.5050
SPRY / ARS Pharmaceuticals, Inc. 8.29 0.00 144.63 38.71 3.6045 1.1187
SYK / Stryker Corporation 0.36 0.00 142.11 6.28 3.5416 0.3539
EW / Edwards Lifesciences Corporation 1.71 11.49 133.58 20.30 3.3290 0.6819
ARGX / argenx SE - Depositary Receipt (Common Stock) 0.21 0.63 114.65 -6.28 2.8573 -0.0592
ALNY / Alnylam Pharmaceuticals, Inc. 0.34 -1.21 111.49 19.30 2.7785 0.5505
UNH / UnitedHealth Group Incorporated 0.34 67.15 104.92 -0.44 2.6202 0.1080
NTRA / Natera, Inc. 0.59 8.49 100.25 29.61 2.4985 0.6544
VRTX / Vertex Pharmaceuticals Incorporated 0.21 31.51 93.62 20.76 2.3331 0.4850
THC / Tenet Healthcare Corporation 0.47 0.00 81.84 30.86 2.0439 0.5529
CAI / Caris Life Sciences, Inc. 3.03 81.09 2.0252 2.0252
IRON / Disc Medicine, Inc. 1.42 0.00 74.94 6.69 1.8716 0.1970
AVBP / ArriVent BioPharma, Inc. 3.03 0.00 65.90 17.74 1.6424 0.3080
SION / Sionna Therapeutics, Inc. 3.70 0.00 64.28 65.87 1.6054 0.6815
UPB / Upstream Bio, Inc. 5.69 0.00 62.52 79.41 1.5580 0.7273
NBIX / Neurocrine Biosciences, Inc. 0.44 -53.08 55.12 -46.68 1.3737 -1.0907
ITGR / Integer Holdings Corporation 0.43 -34.58 53.30 -31.83 1.3282 -0.5357
RNA / Avidity Biosciences, Inc. 1.81 0.00 51.49 -3.80 1.2831 0.0073
CGON / CG Oncology, Inc. 1.88 -24.04 48.82 -19.35 1.2193 -0.2239
SIBN / SI-BONE, Inc. 2.58 -25.09 48.54 0.48 1.2096 0.0580
MBX / MBX Biosciences, Inc. 4.00 0.00 45.67 54.61 1.1382 0.4340
AXSM / Axsome Therapeutics, Inc. 0.43 10.65 44.67 -0.96 1.1132 0.0380
CMPX / Compass Therapeutics, Inc. 15.22 -31.94 39.57 -6.87 0.9862 -0.0268
CYTK / Cytokinetics, Incorporated 1.08 -28.64 35.58 -41.33 0.8868 -0.5592
CRNX / Crinetics Pharmaceuticals, Inc. 1.15 15.02 33.05 -1.38 0.8235 0.0247
EXAS / Exact Sciences Corporation 0.61 -10.66 32.27 9.66 0.8043 0.1027
THRD / Third Harmonic Bio, Inc. 5.78 0.00 31.38 56.49 0.7820 0.3040
ROIV / Roivant Sciences Ltd. 2.78 31.32 0.7823 0.7823
XENE / Xenon Pharmaceuticals Inc. 0.95 0.00 29.67 -6.71 0.7394 -0.0188
NPCE / NeuroPace, Inc. 2.61 -23.26 29.12 -30.43 0.7258 -0.2723
CRVS / Corvus Pharmaceuticals, Inc. 7.17 3.19 28.66 29.80 0.7142 0.1878
TERN / Terns Pharmaceuticals, Inc. 7.56 0.00 28.21 35.15 0.7030 0.2054
JANX / Janux Therapeutics, Inc. 1.21 59.55 27.96 36.50 0.6967 0.2085
APLS / Apellis Pharmaceuticals, Inc. 1.48 3.49 25.66 -18.09 0.6394 -0.1073
GPCR / Structure Therapeutics Inc. - Depositary Receipt (Common Stock) 1.20 83.93 24.87 120.39 0.6199 0.3508
SCPH / scPharmaceuticals Inc. 6.06 0.00 23.09 44.87 0.5766 0.1967
CTMX / CytomX Therapeutics, Inc. 8.46 19.21 0.4787 0.4787
TMO / Thermo Fisher Scientific Inc. 0.05 -63.95 18.85 -70.63 0.4699 -1.0604
AGIO / Agios Pharmaceuticals, Inc. 0.56 71.40 18.56 94.56 0.4624 0.2351
TRVI / Trevi Therapeutics, Inc. 3.31 195.39 18.10 156.90 0.4510 0.2831
ADCT / ADC Therapeutics SA 5.91 -1.02 15.83 88.13 0.3945 0.1939
RYTM / Rhythm Pharmaceuticals, Inc. 0.25 -34.60 15.70 -21.98 0.3913 -0.0885
UNH / UnitedHealth Group Incorporated Call 0.05 15.60 0.3896 0.3896
FBRX / Forte Biosciences, Inc. 1.20 101.82 15.48 236.29 0.3857 0.2760
CGEM / Cullinan Therapeutics, Inc. 1.92 0.00 14.49 -0.53 0.3618 0.0146
KROS / Keros Therapeutics, Inc. 1.02 0.00 13.60 31.02 0.3397 0.0922
RAPT / RAPT Therapeutics, Inc. 1.64 13.14 0.0000
IKENA ONCOLOGY INC / NONVOTING (000000000) 12.05 13.13 0.0000
FOLD / Amicus Therapeutics, Inc. 2.29 0.00 13.10 -29.78 0.3264 -0.1182
VIR / Vir Biotechnology, Inc. 2.38 5.89 12.00 -17.64 0.2990 -0.0483
ABCL / AbCellera Biologics Inc. 3.34 -20.00 11.47 23.04 0.2865 0.0642
AKRO / Akero Therapeutics, Inc. 0.21 17.45 11.27 54.82 0.2810 0.1074
MLYS / Mineralys Therapeutics, Inc. 0.76 10.29 0.2564 0.2564
DYN / Dyne Therapeutics, Inc. 1.03 1.65 9.82 -7.48 0.2447 -0.0083
CCCC / C4 Therapeutics, Inc. 6.83 0.00 9.77 -10.62 0.2439 -0.0166
ORIC / ORIC Pharmaceuticals, Inc. 0.90 28.47 9.13 133.67 0.2275 0.1344
CPRX / Catalyst Pharmaceuticals, Inc. 0.42 9.05 0.2255 0.2255
PRLD / Prelude Therapeutics Incorporated 10.91 0.00 8.83 5.38 0.2205 0.0208
CRBP / Corbus Pharmaceuticals Holdings, Inc. 1.17 0.00 8.09 29.95 0.2020 0.0536
ZLAB / Zai Lab Limited - Depositary Receipt (Common Stock) 0.23 8.08 0.2013 0.2013
TARS / Tarsus Pharmaceuticals, Inc. 0.20 -69.73 8.02 -76.13 0.1998 -0.6008
WHWK / Whitehawk Therapeutics, Inc. 4.17 0.00 7.79 5.06 0.1941 0.0174
TYRA / Tyra Biosciences, Inc. 0.80 -54.10 7.70 -52.76 0.1919 -0.1967
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call 0.10 6.99 0.1741 0.1741
ACET / Adicet Bio, Inc. 11.45 0.00 6.98 -19.21 0.1744 -0.0316
ITOS / iTeos Therapeutics, Inc. 0.70 6.98 0.1743 0.1743
PMVP / PMV Pharmaceuticals, Inc. 6.48 0.00 6.86 -2.76 0.1714 0.0032
URGN / UroGen Pharma Ltd. 0.48 6.55 0.1637 0.1637
ASND / Ascendis Pharma A/S - Depositary Receipt (Common Stock) 0.03 5.94 0.1483 0.1483
ALMS / Alumis Inc. 1.93 5.78 0.1443 0.1443
JBIO / Jade Biosciences, Inc. 0.53 5.31 0.1325 0.1325
NSPR / InspireMD, Inc. 2.13 0.00 4.84 -15.62 0.1207 -0.0161
AVTX / Avalo Therapeutics, Inc. 0.97 0.00 4.83 -37.70 0.1203 -0.0644
IKNA / Ikena Oncology, Inc. 3.54 0.00 4.74 4.68 0.1184 0.0104
RPTX / Repare Therapeutics Inc. 3.32 0.00 4.62 41.01 0.1153 0.0372
CGON / CG Oncology, Inc. Call 0.15 3.90 0.0974 0.0974
IMTX / Immatics N.V. 0.72 -76.68 3.87 -72.18 0.0965 -0.2354
BIOA / BioAge Labs, Inc. 0.92 0.00 3.81 9.84 0.0949 0.0122
QTTB / Q32 Bio Inc. 2.25 0.00 3.36 -9.71 0.0838 -0.0048
ENGN / enGene Holdings Inc. 0.68 -23.96 2.47 -38.23 0.0615 -0.0337
PASG / Passage Bio, Inc. 6.06 -13.92 2.42 -2.42 0.0604 0.0012
AMLX / Amylyx Pharmaceuticals, Inc. 0.31 -10.00 2.01 63.04 0.0500 0.0207
MURA / Mural Oncology plc 0.59 1.45 0.0363 0.0363
INSM / Insmed Incorporated 0.01 -53.04 1.35 -38.06 0.0338 -0.0184
KRYS / Krystal Biotech, Inc. 0.01 -60.85 1.26 -70.17 0.0315 -0.0695
TSBX / Turnstone Biologics Corp. 3.10 0.00 1.11 -12.44 0.0278 -0.0025
CMMB / Chemomab Therapeutics Ltd. - Depositary Receipt (Common Stock) 0.94 -45.96 1.09 -42.49 0.0273 -0.0180
TRAW / Traws Pharma, Inc. 0.61 0.00 0.90 -35.63 0.0224 -0.0108
KZR / Kezar Life Sciences, Inc. 0.19 0.00 0.88 -6.17 0.0220 -0.0004
APLS / Apellis Pharmaceuticals, Inc. Call 0.05 0.87 0.0216 0.0216
ANRO / Alto Neuroscience, Inc. 0.25 0.00 0.55 1.85 0.0137 0.0008
DHAI / DIH Holding US, Inc. 1.92 0.00 0.47 5.88 0.0117 0.0012
LYEL / Lyell Immunopharma, Inc. 0.05 0.46 0.0114 0.0114
KRRO / Korro Bio, Inc. 0.03 0.00 0.40 -28.37 0.0101 -0.0034
XERS / Xeris Biopharma Holdings, Inc. 0.08 0.00 0.38 -14.97 0.0094 -0.0012
INMB / INmune Bio, Inc. Put 0.05 0.12 0.0029 0.0029
LSB / LakeShore Biopharma Co., Ltd 0.05 -60.98 0.06 -84.01 0.0014 -0.0068
CBLL / CeriBell, Inc. 0.00 -100.00 0.00 0.0000
GILD / Gilead Sciences, Inc. 0.00 -100.00 0.00 -100.00 -0.5276
SLRN / Acelyrin, Inc. 0.00 -100.00 0.00 0.0000
CRDF / Cardiff Oncology, Inc. 0.00 -100.00 0.00 -100.00 -0.0430
KMTS / Kestra Medical Technologies, Ltd. 0.00 -100.00 0.00 0.0000
TNGX / Tango Therapeutics, Inc. 0.00 -100.00 0.00 0.0000
NKTX / Nkarta, Inc. 0.00 -100.00 0.00 0.0000
PHGE / BiomX Inc. 0.00 -100.00 0.00 -100.00 -0.0237
SWTX / SpringWorks Therapeutics, Inc. 0.00 -100.00 0.00 0.0000
FATE / Fate Therapeutics, Inc. 0.00 -100.00 0.00 -100.00 -0.0317
XTNT / Xtant Medical Holdings, Inc. 0.00 -100.00 0.00 0.0000
SRRK / Scholar Rock Holding Corporation 0.00 -100.00 0.00 0.0000
XFOR / X4 Pharmaceuticals, Inc. 0.00 -100.00 0.00 0.0000
XBI / SPDR Series Trust - SPDR S&P Biotech ETF Call 0.00 -100.00 0.00 -100.00 -0.1933
TIL / Instil Bio, Inc. 0.00 -100.00 0.00 -100.00 -0.0483
AMGN / Amgen Inc. 0.00 -100.00 0.00 0.0000
SWTX / SpringWorks Therapeutics, Inc. Call 0.00 -100.00 0.00 0.0000
NXTC / NextCure, Inc. 0.00 -100.00 0.00 0.0000
BCAX / Bicara Therapeutics Inc. 0.00 -100.00 0.00 0.0000
VERA / Vera Therapeutics, Inc. 0.00 -100.00 0.00 0.0000
IVVD / Invivyd, Inc. 0.00 -100.00 0.00 0.0000
VSTM / Verastem, Inc. 0.00 -100.00 0.00 -100.00 -0.4115
PFE / Pfizer Inc. 0.00 -100.00 0.00 0.0000
IONS / Ionis Pharmaceuticals, Inc. 0.00 -100.00 0.00 0.0000
PFE / Pfizer Inc. Call 0.00 -100.00 0.00 0.0000
RAPT / RAPT Therapeutics, Inc. 0.00 -100.00 0.00 0.0000
GPCR / Structure Therapeutics Inc. - Depositary Receipt (Common Stock) Call 0.00 -100.00 0.00 0.0000