ATHA / Athira Pharma, Inc. - Pemfailan SEC, Laporan Tahunan, Penyata Proksi

Athira Pharma, Inc.
US ˙ NasdaqCM ˙ US04746L1044

Statistik Asas
CIK 1620463
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Athira Pharma, Inc.
SEC Filings (Chronological Order)
Halaman ini menyediakan senarai kronologi lengkap bagi Pemfailan SEC, tidak termasuk pemfailan pemilikan yang kami sediakan di tempat lain.
August 7, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

August 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2025 Athira Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2025 Athira Pharma, Inc.

August 7, 2025 EX-99.1

Athira Pharma Reports Second Quarter 2025 Financial Results and Provides Business Update Data from Phase 1 clinical trial of ATH-1105 in healthy volunteers showed a favorable safety and tolerability profile; dose proportional pharmacokinetics and CNS

Exhibit 99.1 Athira Pharma Reports Second Quarter 2025 Financial Results and Provides Business Update Data from Phase 1 clinical trial of ATH-1105 in healthy volunteers showed a favorable safety and tolerability profile; dose proportional pharmacokinetics and CNS penetration support continued clinical development BOTHELL, Wash., August 7, 2025 – Athira Pharma, Inc. (NASDAQ: ATHA), a clinical stage

June 2, 2025 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 29, 2025 Athira Pharma, Inc.

May 9, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

May 9, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2025 Athira Pharma, Inc.

May 9, 2025 EX-99.1

Athira Pharma Reports First Quarter 2025 Financial Results and Pipeline and Business Updates Completed healthy volunteer Phase 1 clinical study of ATH-1105 as a potential treatment for amyotrophic lateral sclerosis (ALS); full healthy volunteer data

Exhibit 99.1 Athira Pharma Reports First Quarter 2025 Financial Results and Pipeline and Business Updates Completed healthy volunteer Phase 1 clinical study of ATH-1105 as a potential treatment for amyotrophic lateral sclerosis (ALS); full healthy volunteer data expected in 2H25 On-track to enable dosing ALS patients in late 2025 BOTHELL, Wash., May 9, 2025 – Athira Pharma, Inc. (NASDAQ: ATHA), a

April 16, 2025 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 15, 2025 Athira Pharma, Inc.

April 14, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:  ☐  Preliminary Proxy Statement   ☐  Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))  

April 14, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:   ☐  Preliminary Proxy Statement   ☐  Confidential, for Use of the Commission Only (as permitted by

April 4, 2025 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:  ☒  Preliminary Proxy Statement   ☐  Confidential, for Use of the Commission Only (as permitted by R

February 27, 2025 EX-10.10

Outside Director Compensation Policy, as amended

Exhibit 10.10 ATHIRA PHARMA, INC. OUTSIDE DIRECTOR COMPENSATION POLICY As amended and restated on September 12, 2024 Athira Pharma, Inc. (the “Company”) believes that the granting of equity and cash compensation to members of the Company’s Board of Directors (the “Board,” and members of the Board, “Directors”) represents an effective tool to attract, retain and reward Directors who are not employe

February 27, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 27, 2025 Athira Pharma, Inc.

February 27, 2025 EX-4.2

Description of Capital Stock

Exhibit 4.2 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 As of December 31, 2024, we had one class of securities, our common stock, registered under Section 12 of the Securities Exchange Act of 1934, as amended. These securities are listed on the Nasdaq Global Select Market under the symbol “ATHA.” Our authorized capital stock

February 27, 2025 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Athira Pharma, Inc.

February 27, 2025 EX-19

Insider Trading Policy, as amended

Exhibit 19 ATHIRA PHARMA, INC. INSIDER TRADING POLICY (As amended and restated on September 12, 2024) A. POLICY OVERVIEW Athira Pharma, Inc. (together with any subsidiaries, collectively the “Company”) has adopted this Insider Trading Policy (the “Policy”) to help you comply with the federal and state securities laws and regulations that govern trading in securities and to help the Company minimiz

February 27, 2025 S-8

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S‑8 REGISTRATION STATEMENT The Securities Act of 1933 ATHIRA PHARMA, INC. (Exact name of Registrant as specified in its charter)

As filed with the Securities and Exchange Commission on February 27, 2025 Registration No.

February 27, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39503 Athira Pharma,

February 27, 2025 EX-97

Amended and Restated Compensation Recovery Policy

Exhibit 97 ATHIRA PHARMA, INC. COMPENSATION RECOVERY (“CLAWBACK”) POLICY (As amended and restated on September 12, 2024) Athira Pharma, Inc. (the “Company”) is committed to strong corporate governance. As part of this commitment, the Company’s Board of Directors (the “Board”) has adopted this Amended and Restated Compensation Recovery (“Clawback”) Policy (the “Policy”). The Policy is intended to f

February 27, 2025 EX-99.1

Athira Pharma Reports Full Year 2024 Financial Results and Pipeline and Business Updates Completed healthy volunteer Phase 1 clinical study of ATH-1105 as a potential treatment for amyotrophic lateral sclerosis (ALS) On-track to enable dosing ALS pat

Exhibit 99.1 Athira Pharma Reports Full Year 2024 Financial Results and Pipeline and Business Updates Completed healthy volunteer Phase 1 clinical study of ATH-1105 as a potential treatment for amyotrophic lateral sclerosis (ALS) On-track to enable dosing ALS patients in 2025 BOTHELL, Wash., February 27, 2025 – Athira Pharma, Inc. (NASDAQ: ATHA), a clinical stage biopharmaceutical company focused

November 14, 2024 SC 13G/A

ATHA / Athira Pharma, Inc. / BAKER BROS. ADVISORS LP - SC 13G/A Passive Investment

SC 13G/A 1 tm2426483d3sc13ga.htm SC 13G/A SCHEDULE 13G SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Under the Securities Exchange Act of 1934 (Amendment No. 1)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 04746L104 (CUSIP Number) September 30, 2024 (Date of Event which Requires Filing of this Statement) Check the appropri

November 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

November 7, 2024 SC 13G

ATHA / Athira Pharma, Inc. / BML Investment Partners, L.P. Passive Investment

SC 13G 1 atha13g.htm SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2 (AMENDMENT NO. )* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L104 (CUSIP Number) November

November 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2024 Athira Pharma, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2024 Athira Pharma, Inc.

November 7, 2024 EX-99.1

Athira Pharma Reports Third Quarter 2024 Financial Results and Pipeline and Business Updates Expects to complete healthy volunteer Phase 1 clinical study of ATH-1105 by year end and begin dosing ALS patients in 2025

Exhibit 99.1 Athira Pharma Reports Third Quarter 2024 Financial Results and Pipeline and Business Updates Expects to complete healthy volunteer Phase 1 clinical study of ATH-1105 by year end and begin dosing ALS patients in 2025 BOTHELL, Wash., November 7, 2024 – Athira Pharma, Inc. (NASDAQ: ATHA), a clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal

October 31, 2024 SC 13D/A

ATHA / Athira Pharma, Inc. / PERCEPTIVE ADVISORS LLC - SC 13D/A Activist Investment

SC 13D/A SECURITIES AND EXCHANGE COMMISSION  Washington, D.C. 20549  SCHEDULE 13D/A  Under the Securities Exchange Act of 1934 (Amendment No. 3)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L104 (CUSIP Number) Alexander Rakitin Perceptive Advisors LLC 51 Astor Place, 10th Floor New York, NY 10003 (646) 205-5340 (Name, Address and Telepho

October 24, 2024 CORRESP

October 24, 2024

October 24, 2024 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549-3720 Attention: Alan Campbell Re: Athira Pharma, Inc. Registration Statement on Form S-3 Filed October 21, 2024 (File No. 333-282738) Acceleration Request Requested Date: October 28, 2024 Requested Time: 4:00 P.M. Eastern Daylight Time

October 21, 2024 EX-4.3

Form of Indenture

Exhibit 4.3 ATHIRA PHARMA, INC. INDENTURE Dated as of , 20 [] Trustee TABLE OF CONTENTS Page ARTICLE I DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1 Definitions 1 Section 1.2 Other Definitions 4 Section 1.3 Incorporation by Reference of Trust Indenture Act 4 Section 1.4 Rules of Construction 5 ARTICLE II THE SECURITIES 5 Section 2.1 Issuable in Series 5 Section 2.2 Establishment of Term

October 21, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Athira Pharma, Inc.

October 21, 2024 S-3

As filed with the Securities and Exchange Commission on October 18, 2024

As filed with the Securities and Exchange Commission on October 18, 2024 Registration No.

October 18, 2024 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 16, 2024 Athira Pharma, Inc.

October 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 1, 2024 Athira Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 1, 2024 Athira Pharma, Inc.

October 7, 2024 EX-10.1

Separation Agreement and Release between Andrew Gengos and Athira Pharma, Inc. dated October 3, 2024

*Certain portions of this exhibit have been omitted because they are not material and is the type of information that the company treats as private or confidential.

October 7, 2024 EX-10.2

Separation Agreement and Release between Rachel Lenington and Athira Pharma, Inc. dated October 1, 2024

*Certain portions of this exhibit have been omitted because they are not material and is the type of information that the company treats as private or confidential.

September 17, 2024 EX-10.2

Change in Control Agreement between the Registrant and Robert Renninger.

Exhibit 10.2 ATHIRA PHARMA, INC. CHANGE IN CONTROL AGREEMENT This Change in Control Agreement (the “Agreement”) is made by and between Athira Pharma, Inc., a Delaware corporation (the “Company”), and Robert Renninger (“Executive”), effective as of , 2023 (the “Effective Date”). This Agreement provides certain protections to Executive in connection with an involuntary termination of Executive’s emp

September 17, 2024 EX-99.1

Athira Pharma to Focus on Advancement of ATH-1105 for the Treatment of Neurodegenerative Diseases ATH-1105 is an orally delivered, positive modulator of the neurotrophic HGF system that is currently in a Phase 1 clinical trial with completion expecte

Exhibit 99.1 Athira Pharma to Focus on Advancement of ATH-1105 for the Treatment of Neurodegenerative Diseases ATH-1105 is an orally delivered, positive modulator of the neurotrophic HGF system that is currently in a Phase 1 clinical trial with completion expected by year end 2024 and commencement of dosing of ALS patients expected in 2025 Company announces cost containment measures in alignment w

September 17, 2024 EX-10.1

Employment Offer Letter between the Registrant and Robert Renninger.

Exhibit 10.1 4000 MASON RD SUITE 300, BOX 352141 SEATTLE, WA 98195-2141 June 21, 2020 Robert Renninger 415 West Crockett Street Seattle, WA 98119 Dear Mr. Renninger, We are pleased to offer you a position with Athira Pharma, Inc, (the “Company”) as Director of Accounting & Reporting. If you decide to join us, you will become part of a fast-paced and dedicated team that works together to accelerate

September 17, 2024 8-K

Financial Statements and Exhibits, Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 15, 2024 Athira Pharma, Inc.

September 3, 2024 EX-99.2

3 Therapeutic Potential of HGF Positive Modulation as a Neurotrophic Factor for Neurodegenerative Diseases HGF, hepatocyte growth factor. Potential first-in-class small molecule drug candidates Able to cross the blood-brain barrier Positively modulat

LIFT-AD Topline Readout September 3, 2024 Exhibit 99.2 Disclaimer This presentation and the accompanying oral commentary contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Forward-looking stateme

September 3, 2024 EX-99.1

Athira Pharma Announces Topline Results from Phase 2/3 LIFT-AD Clinical Trial of Fosgonimeton for Mild-to-Moderate Alzheimer’s Disease  LIFT-AD trial did not meet primary endpoint of GST and key secondary endpoints of cognition (ADAS-Cog11) and funct

Exhibit 99.1 Athira Pharma Announces Topline Results from Phase 2/3 LIFT-AD Clinical Trial of Fosgonimeton for Mild-to-Moderate Alzheimer’s Disease    LIFT-AD trial did not meet primary endpoint of GST and key secondary endpoints of cognition (ADAS-Cog11) and function (ADCS-ADL23) In pre-specified subgroups of patients with moderate Alzheimer’s disease or who are APOE4 carriers, fosgonimeton showe

September 3, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 3, 2024 Athira Pharma, Inc.

August 9, 2024 EX-10.2

Change in Control and Severance Agreement between the Registrant and Javier San Martin

Exhibit 10.2 ATHIRA PHARMA, INC. CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Change in Control and Severance Agreement (the “Agreement”) is made by and between Athira Pharma, Inc., a Delaware corporation (the “Company”), and Javier San Martin (“Executive”), effective as of April 15, 2024 (the “Effective Date”). This Agreement provides certain protections to Executive in connection with an invol

August 9, 2024 EX-10.1

Employment Offer Letter between the Registrant and Javier San Martin

Exhibit 10.1 18706 NORTH CREEK PARKWAY SUITE 104 BOTHELL, WA 98011 March 29, 2024 Javier San Martin [Address] Email: [Email] Dear Javier: We are pleased to offer you employment with Athira Pharma, Inc. (the “Company”) as its Chief Medical Officer, reporting to the Company’s Chief Executive Officer (“CEO”). If you decide to join us in this role, you will become part of a fast-paced and dedicated te

August 9, 2024 10-Q/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q/A (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q/A (Amendment No.

August 1, 2024 EX-99.1

Athira Pharma Reports Second Quarter 2024 Financial Results and Pipeline and Business Updates Topline data from completed Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease targeted for

Exhibit 99.1 Athira Pharma Reports Second Quarter 2024 Financial Results and Pipeline and Business Updates Topline data from completed Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease targeted for September 2024 Phase 2/3 LIFT-AD data to be presented in an oral presentation at CTAD in October 2024 Phase 1 clinical trial of ATH-1105

August 1, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2024 Athira Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2024 Athira Pharma, Inc.

August 1, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

May 29, 2024 EX-3.1

Certificate of Amendment to the Amended and Restated Certificate of Incorporation of the Company dated May 23, 2024

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO THE AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF ATHIRA PHARMA, INC. Athira Pharma, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), does hereby certify as follows: 1. The Company was originally incorporated under the name of M3 Biotechnology, Inc., and the original Certificate of Incorporation of th

May 29, 2024 8-K

Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2024 Athira Pharma, Inc.

May 17, 2024 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2024 Athira Pharma, Inc.

May 17, 2024 EX-99.1

Athira Pharma Announces Proposed Settlement of Stockholder Derivative Action

Exhibit 99.1 Athira Pharma Announces Proposed Settlement of Stockholder Derivative Action BOTHELL, WA, May 17, 2024 — Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and slow neurodegeneration, today announced that the U.S. District Court for the Western District of Washington issued an order provi

May 15, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

May 15, 2024 EX-99.1

Athira Pharma Reports First Quarter 2024 Financial Results and Pipeline and Business Updates Topline data from Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease expected in second half

Exhibit 99.1 Athira Pharma Reports First Quarter 2024 Financial Results and Pipeline and Business Updates Topline data from Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease expected in second half of 2024 Submitted Investigational New Drug application to U.S. Food and Drug Administration for ATH-1105 for the treatment of amyotrophic

May 15, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2024 Athira Pharma, Inc.

April 9, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defi

April 9, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:   ☐  Preliminary Proxy Statement   ☐  Confidential, for Use of the Commission Only (as permitted by

March 28, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549   SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:  ☒  Preliminary Proxy Statement   ☐  Confidential, for Use of the Commission Only (as permitted by R

February 22, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39503 Athira Pharma,

February 22, 2024 S-8

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S‑8 REGISTRATION STATEMENT The Securities Act of 1933 ATHIRA PHARMA, INC. (Exact name of Registrant as specified in its charter)

As filed with the Securities and Exchange Commission on February 22, 2024 Registration No.

February 22, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 21, 2024 Athira Pharma, Inc.

February 22, 2024 EX-97

Amended and Restated Compensation Recovery Policy

ATHIRA PHARMA, INC. AMENDED AND RESTATED COMPENSATION RECOVERY (“CLAWBACK”) POLICY As amended and restated on November 13, 2023 Athira Pharma, Inc. (the “Company”) is committed to strong corporate governance. As part of this commitment, the Company’s Board of Directors (the “Board”) has adopted this Amended and Restated Compensation Recovery (“Clawback”) Policy (the “Policy”). The Policy is intend

February 22, 2024 EX-99.1

Athira Pharma Reports Full Year 2023 Financial Results and Pipeline and Business Updates Enrollment completed in Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease; topline data expected

Exhibit 99.1 Athira Pharma Reports Full Year 2023 Financial Results and Pipeline and Business Updates Enrollment completed in Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease; topline data expected in second half of 2024 On track to initiate first-in-human studies of ATH-1105 for the treatment of amyotrophic lateral sclerosis in fir

February 22, 2024 EX-10.1

2024 Inducement Equity Incentive Plan and related form agreements

Exhibit 10.1 ATHIRA PHARMA, INC. 2024 INDUCEMENT EQUITY INCENTIVE PLAN 1. Purposes of the Plan. The purposes of this Plan are to attract and retain the best available personnel for positions of substantial responsibility by providing an inducement material to individuals entering into employment with the Company or any Parent or Subsidiary of the Company. The Plan permits the grant of Nonstatutory

February 22, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Athira Pharma, Inc.

February 22, 2024 EX-4.3

Description of Capital Stock

Exhibit 4.3 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 As of December 31, 2023, we had one class of securities, our common stock, registered under Section 12 of the Securities Exchange Act of 1934, as amended. These securities are listed on the Nasdaq Global Select Market under the symbol “ATHA.” Our authorized capital stock

February 14, 2024 EX-99.1

AGREEMENT

EX-99.1 2 tm242424d30ex99-1.htm EXHIBIT 99.1 EXHIBIT 99.1 AGREEMENT In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that this Statement on Schedule 13G relating to the Common Stock of Athira Pharma, Inc. is being filed with the Securities and Exchange Commission on behalf of each of them. February 14, 2024 BAKER BROS. ADVISORS

February 14, 2024 SC 13G

ATHA / Athira Pharma, Inc. / BAKER BROS. ADVISORS LP - SC 13G Passive Investment

SC 13G 1 tm242424d30sc13g.htm SC 13G SCHEDULE 13G SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Under the Securities Exchange Act of 1934 (Amendment No. )* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box

January 8, 2024 EX-99.1

Athira Pharma Provides 2024 Clinical Pipeline Outlook and Business Update Completed enrollment in Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease and expects topline data in second ha

Exhibit 99.1 Athira Pharma Provides 2024 Clinical Pipeline Outlook and Business Update Completed enrollment in Phase 2/3 LIFT-AD clinical trial of fosgonimeton as a potential treatment for mild-to-moderate Alzheimer’s disease and expects topline data in second half of 2024 Plans to initiate first-in-human studies of ATH-1105 to treat amyotrophic lateral sclerosis in first half of 2024 BOTHELL, WA,

January 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2024 Athira Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2024 Athira Pharma, Inc.

January 8, 2024 EX-10.1

Executive Transition Agreement between the Registrant and Hans Moebius dated January 5, 2024

Exhibit 10.1 EXECUTIVE TRANSITION AGREEMENT THIS EXECUTIVE TRANSITION AGREEMENT (this “Agreement”) is entered into as of January 5, 2024 (the “Effective Date”) between Athira Pharma, Inc. (the “Company”) and Hans Moebius (“Executive”) (collectively referred to as the “Parties” or individually referred to as a “Party”). R E C I T A L S WHEREAS, the Parties previously entered into an “Offer of Emplo

December 29, 2023 SC 13D/A

ATHA / Athira Pharma, Inc. / PERCEPTIVE ADVISORS LLC - SC 13D/A Activist Investment

SC 13D/A 1 d134543dsc13da.htm SC 13D/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L 104 (CUSIP Number) Alexander Rakitin Perceptive Advisors LLC 51 Astor Place, 10th Floor New York, NY 10003 (646) 205-534

November 9, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2023 Athira Pharma, Inc.

November 9, 2023 EX-99.1

Athira Pharma Reports Third Quarter 2023 Financial Results and Pipeline and Business Updates Continues to report clinical and preclinical findings supporting the potential benefits of its small molecule therapeutic candidates targeting the neurotroph

Exhibit 99.1 Athira Pharma Reports Third Quarter 2023 Financial Results and Pipeline and Business Updates Continues to report clinical and preclinical findings supporting the potential benefits of its small molecule therapeutic candidates targeting the neurotrophic HGF system as potential novel treatments for neurodegenerative diseases Expects to complete enrollment of Phase 2/3 LIFT-AD clinical t

November 9, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

August 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2023 Athira Pharma, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2023 Athira Pharma, Inc.

August 10, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

August 10, 2023 EX-99.1

Athira Pharma Reports Second Quarter 2023 Financial Results and Pipeline and Business Updates Completed end of Phase 2 meeting and continued engagement with U.S. Food and Drug Administration Appointed Andrew Gengos as Chief Financial Officer and Chie

Exhibit 99.1 Athira Pharma Reports Second Quarter 2023 Financial Results and Pipeline and Business Updates Completed end of Phase 2 meeting and continued engagement with U.S. Food and Drug Administration Appointed Andrew Gengos as Chief Financial Officer and Chief Business Officer Maintains strong balance sheet to support innovative clinical development pipeline in neurodegenerative diseases throu

May 22, 2023 EX-10.3

Transition Services Agreement between the Company and Glenna Mileson, dated as of May 18, 2023.

EX-10.3 Exhibit 10.3 TRANSITION AGREEMENT AND RELEASE This Transition Agreement and Release (“Agreement”) is made by and between Glenna Mileson (“Employee”) and Athira Pharma, Inc. (the “Company”) (collectively referred to as the “Parties” or individually referred to as a “Party”). WHEREAS, Employee has been employed at-will by the Company as its Chief Financial Officer (“CFO”); WHEREAS, Employee

May 22, 2023 EX-99.1

Athira Pharma Appoints Andrew Gengos as Chief Financial Officer and Chief Business Officer Veteran biopharmaceutical executive brings over 30 years of financial, corporate strategy, transactional and business development experience

EX-99.1 Exhibit 99.1 Athira Pharma Appoints Andrew Gengos as Chief Financial Officer and Chief Business Officer Veteran biopharmaceutical executive brings over 30 years of financial, corporate strategy, transactional and business development experience BOTHELL, WA, May 22, 2023 — Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage biopharmaceutical company focused on developing small molecul

May 22, 2023 EX-10.1

Employment Offer Letter between the Company and Andrew Gengos, dated as of May 18, 2023.

EX-10.1 Exhibit 10.1 18706 NORTH CREEK PARKWAY SUITE 104 BOTHELL, WA 98011 May 18, 2023 Andrew Gengos [Address] [Email] Dear Andrew: We are pleased to offer you a position with Athira Pharma, Inc. (the “Company”). If you decide to join us, you will become part of a fast-paced and dedicated team that works together to accelerate the development of life changing therapeutics. Effective as of Thursda

May 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2023 Athira Pharma, Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2023 Athira Pharma, Inc.

May 22, 2023 EX-10.2

Change in Control and Severance Agreement between the Company and Andrew Gengos, dated as of May 18, 2023.

EX-10.2 Exhibit 10.2 ATHIRA PHARMA, INC. CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Change in Control and Severance Agreement (the “Agreement”) is made by and between Athira Pharma, Inc., a Delaware corporation (the “Company”), and Andrew Gengos (“Executive”), effective as of May 18, 2023 (the “Effective Date”). This Agreement provides certain protections to Executive in connection with an inv

May 11, 2023 EX-99.1

Athira Pharma Reports First Quarter 2023 Financial Results and Recent Pipeline and Business Updates Phase 2/3 LIFT-AD trial of fosgonimeton for mild-to-moderate Alzheimer’s disease to focus on 40 mg dose Open label extension trial to be extended, pro

Exhibit 99.1 Athira Pharma Reports First Quarter 2023 Financial Results and Recent Pipeline and Business Updates Phase 2/3 LIFT-AD trial of fosgonimeton for mild-to-moderate Alzheimer’s disease to focus on 40 mg dose Open label extension trial to be extended, providing up to 36 months of long-term exposure data ATH-1105 significantly prolongs survival and improves motor function in a mouse model o

May 11, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

May 11, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 Athira Pharma, Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 Athira Pharma, Inc.

April 20, 2023 SC 13G

ATHA / Athira Pharma Inc / Kayne Richard A - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L104 (CUSIP Number) April 10, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to

April 5, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-

April 5, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definit

March 23, 2023 EX-4

Description of Capital Stock

Exhibit 4.3 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 As of December 31, 2022, we had one class of securities, our common stock, registered under Section 12 of the Securities Exchange Act of 1934, as amended. These securities are listed on the Nasdaq Global Select Market under the symbol “ATHA.” Our authorized capital stock

March 23, 2023 EX-99

Athira Pharma Reports Full Year 2022 Financial Results and Recent Pipeline and Business Updates On track to complete enrollment in Phase 2/3 LIFT-AD trial of fosgonimeton for mild-to-moderate Alzheimer’s disease in mid-2023 with topline data in early

Exhibit 99.1 Athira Pharma Reports Full Year 2022 Financial Results and Recent Pipeline and Business Updates On track to complete enrollment in Phase 2/3 LIFT-AD trial of fosgonimeton for mild-to-moderate Alzheimer’s disease in mid-2023 with topline data in early 2024 Continuing to advance development of ATH-1105 as a potential clinical candidate for amyotrophic lateral sclerosis Strong balance sh

March 23, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Athira Pharma, Inc.

March 23, 2023 S-8

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S‑8 REGISTRATION STATEMENT The Securities Act of 1933 ATHIRA PHARMA, INC. (Exact name of Registrant as specified in its charter)

As filed with the Securities and Exchange Commission on March 23, 2023 Registration No.

March 23, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 23, 2023 Athira Pharma, Inc.

March 23, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39503 Athira Pharma,

March 23, 2023 EX-10

Outside Director Compensation Policy, as amended

Exhibit 10.10 ATHIRA PHARMA, INC. OUTSIDE DIRECTOR COMPENSATION POLICY As amended January 27, 2023 Athira Pharma, Inc. (the “Company”) believes that the granting of equity and cash compensation to members of the Company’s Board of Directors (the “Board,” and members of the Board, “Directors”) represents an effective tool to attract, retain and reward Directors who are not employees of the Company

March 23, 2023 EX-10

2020 Employee Stock Purchase Plan, as amended and Form of Subscription Agreement thereunder

Exhibit 10.8 ATHIRA PHARMA, INC. 2020 EMPLOYEE STOCK PURCHASE PLAN (Amended and Restated effective November 15, 2022) 1. Purpose. The purpose of the Plan is to provide employees of the Company and its Designated Companies with an opportunity to purchase Common Stock through accumulated Contributions. The Company intends for the Plan to have two components: a component that is intended to qualify a

February 14, 2023 SC 13G/A

ATHA / Athira Pharma Inc / RTW INVESTMENTS, LP - ATHIRA PHARMA, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* Athira Pharma, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2022 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant

January 30, 2023 SC 13G/A

ATHA / Athira Pharma Inc / FRANKLIN RESOURCES INC Passive Investment

athi22a1.htm - Generated by SEC Publisher for SEC Filing CUSIP NO. 04746L104 13G Page 1 of 12 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.1)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2022 (Date of

January 6, 2023 424B5

ATHIRA PHARMA, INC. Up to $75,000,000 Common Stock

424B5 1 athira424b5.htm 424B5 Filed Pursuant to Rule 424(b)(5) Registration No. 333-261073 PROSPECTUS SUPPLEMENT (To prospectus dated November 24, 2021) ATHIRA PHARMA, INC. Up to $75,000,000 Common Stock We have entered into a Controlled Equity OfferingSM Sales Agreement, or the Sales Agreement, with Cantor Fitzgerald & Co., or Cantor Fitzgerald, and BTIG, LLC, or BTIG, dated January 6, 2023, rela

January 6, 2023 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 6, 2023 Athira Pharma, Inc.

January 6, 2023 EX-1.1

Controlled Equity Offering Sales AgreementSM, dated January 6, 2023, among the Registrant, Cantor Fitzgerald & Co. and BTIG, LLC

Exhibit 1.1 ATHIRA PHARMA, INC. Shares of Common Stock (par value $0.0001 per share) Controlled Equity OfferingSM Sales Agreement January 6, 2023 Cantor Fitzgerald & Co. 499 Park Avenue New York, NY 10022 BTIG, LLC 65 East 55th Street New York, NY 10022 Ladies and Gentlemen: Athira Pharma, Inc., a Delaware corporation (the ?Company?), confirms its agreement (this ?Agreement?) with Cantor Fitzgeral

November 18, 2022 EX-3.1

Amended and Restated Bylaws of the Company

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF ATHIRA PHARMA, INC. (initially adopted on October 27, 2015) (amended on September 22, 2020) (as amended on November 15, 2022) TABLE OF CONTENTS Page ARTICLE I - CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II - MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 ADVANCE NOTICE PROCED

November 18, 2022 8-K

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 15, 2022 Athira Pharma, Inc.

November 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

November 10, 2022 EX-99.1

Athira Pharma Reports Third Quarter 2022 Financial Results and Recent Clinical and Corporate Updates Independent, unblinded, interim efficacy and futility analysis of Phase 2/3 LIFT-AD study in mild-to-moderate Alzheimer’s disease patients supports p

Exhibit 99.1 Athira Pharma Reports Third Quarter 2022 Financial Results and Recent Clinical and Corporate Updates Independent, unblinded, interim efficacy and futility analysis of Phase 2/3 LIFT-AD study in mild-to-moderate Alzheimer’s disease patients supports potential clinically meaningful activity of fosgonimeton without background acetylcholinesterase therapy and mitigates program risk Strong

November 10, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 Athira Pharma, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 Athira Pharma, Inc.

October 17, 2022 EX-99.2

Independent Unblinded Interim Analysis Supports Potential Clinically Meaningful Activity of Fosgonimeton WITHOUT BACKGROUND THERAPY and Mitigates Program Risk Phase 2 exploratory ACT-AD study results suggested congruent positive effects Cognition (AD

Phase 2/3 LIFT-AD Interim Analysis Results and Next Steps October 17, 2022 Exhibit 99.

October 17, 2022 EX-99.1

Athira Pharma Advances Phase 2/3 LIFT-AD Clinical Study of Fosgonimeton in Mild-to-Moderate Alzheimer’s Patients Following Independent, Unblinded Interim Analysis Results support potential clinically meaningful activity of fosgonimeton without backgr

Exhibit 99.1 Athira Pharma Advances Phase 2/3 LIFT-AD Clinical Study of Fosgonimeton in Mild-to-Moderate Alzheimer?s Patients Following Independent, Unblinded Interim Analysis Results support potential clinically meaningful activity of fosgonimeton without background therapy and mitigate program risk Updated study well powered for primary endpoint with addition of fewer than 150 patients Company t

October 17, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 17, 2022 Athira Pharma, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 17, 2022 Athira Pharma, Inc.

August 15, 2022 EX-99.1

Athira Pharma Reports Second Quarter 2022 Financial Results and Recent Clinical and Corporate Updates Presented clinical and preclinical data at Alzheimer’s Association International Conference 2022 Strong balance sheet to support clinical developmen

Exhibit 99.1 Athira Pharma Reports Second Quarter 2022 Financial Results and Recent Clinical and Corporate Updates Presented clinical and preclinical data at Alzheimer?s Association International Conference 2022 Strong balance sheet to support clinical development pipeline BOTHELL, WA, August 15, 2022 ? Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage biopharmaceutical company focused on

August 15, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

August 15, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 15, 2022 Athira Pharma, Inc.

July 1, 2022 SC 13D/A

ATHA / Athira Pharma Inc / PERCEPTIVE ADVISORS LLC - SC 13D/A Activist Investment

SC 13D/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L 104 (CUSIP Number) Alexander Rakitin Perceptive Advisors LLC 51 Astor Place, 10th Floor New York, NY 10003 (646) 205-5340 (Name, Address and Telephone

June 22, 2022 EX-99.2

Hans Moebius, M.D., Ph.D. Chief Medical Officer ACT-AD Topline Results © Athira Pharma, Inc. All Rights Reserved.

ACT-AD Topline Results Investor Webinar June 22, 2022 Exhibit 99.2 Forward Looking Statements ? Athira Pharma, Inc. All Rights Reserved. This presentation and the accompanying oral commentary contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on our management?s beliefs and assumptions and on inf

June 22, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 22, 2022 Athira Pharma, Inc.

June 22, 2022 EX-99.1

Athira Pharma Announces Topline Results from ACT-AD Phase 2 Proof of Concept Study of Fosgonimeton in Mild-to-Moderate Alzheimer’s Disease Primary endpoint of change in biomarker ERP P300 latency was not statistically significant for the full study p

Exhibit 99.1 Athira Pharma Announces Topline Results from ACT-AD Phase 2 Proof of Concept Study of Fosgonimeton in Mild-to-Moderate Alzheimer’s Disease Primary endpoint of change in biomarker ERP P300 latency was not statistically significant for the full study population as combination of fosgonimeton and standard-of-care (AChEIs) given together showed potential diminished effect of fosgonimeton

May 24, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 19, 2022 Athira Pharma, Inc.

May 17, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy Statement ? Definitive Additional Materials ? Soliciting Material under ? 240.

May 17, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy Statement ? Definitive Additional Materials ? Soliciting Material under ? 240.

May 16, 2022 EX-99.1

RIC KAYNE SUSPENDS CAMPAIGN TO ELECT HIMSELF AND GEORGE BICKERSTAFF TO ATHIRA PHARMA BOARD OF DIRECTORS Issues Letter to Athira Shareholders Highlighting Continued Need for Oversight in Athira’s Boardroom BLUE Proxy Cards Will Still Be Counted

Exhibit 99.1 RIC KAYNE SUSPENDS CAMPAIGN TO ELECT HIMSELF AND GEORGE BICKERSTAFF TO ATHIRA PHARMA BOARD OF DIRECTORS Issues Letter to Athira Shareholders Highlighting Continued Need for Oversight in Athira?s Boardroom BLUE Proxy Cards Will Still Be Counted NEW YORK ? May 16, 2022 ? Richard A. (Ric) Kayne, who together with his affiliates beneficially owns approximately 4.8% of the outstanding shar

May 16, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

DFAN14A 1 k53130683a.htm DFAN 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☐   Preliminary Proxy Statement ☐   Confidential, for Use of the Commission Only (as permi

May 12, 2022 EX-99.1

Athira Pharma Reports First Quarter 2022 Financial Results and Provides Pipeline and Business Updates On track to report topline data from ACT-AD Phase 2 Alzheimer’s disease study by end of 2Q22

Exhibit 99.1 Athira Pharma Reports First Quarter 2022 Financial Results and Provides Pipeline and Business Updates On track to report topline data from ACT-AD Phase 2 Alzheimer?s disease study by end of 2Q22 BOTHELL, WA, May 12, 2022 ? Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and slow neurod

May 12, 2022 EX-99.1

RIC KAYNE ISSUES LETTER TO ATHIRA SHAREHOLDERS HIGHLIGHTING NEED FOR IMMEDIATE CHANGE TO ATHIRA BOARD Details Poor Decision-Making by Current Athira Board Leading to Destruction of Shareholder Value and Outlines the Urgent Need for Change Urges Athir

Exhibit 99.1 RIC KAYNE ISSUES LETTER TO ATHIRA SHAREHOLDERS HIGHLIGHTING NEED FOR IMMEDIATE CHANGE TO ATHIRA BOARD Details Poor Decision-Making by Current Athira Board Leading to Destruction of Shareholder Value and Outlines the Urgent Need for Change Urges Athira Shareholders to VOTE their BLUE Proxy Card TODAY NEW YORK ? May 12, 2022 ? Richard A. (Ric) Kayne, who together with his affiliates ben

May 12, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a party other than the Registrant ? Check the appropriate box: ????Preliminary Proxy Statement ????Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ??? Defi

May 12, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

May 12, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 12, 2022 Athira Pharma, Inc.

May 11, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy Statement ? Definitive Additional Materials ? Soliciting Material under ? 240.

May 9, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d307346ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☑ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

May 5, 2022 EX-99.1

LEADING PROXY ADVISORY FIRM ISS RECOMMENDS ATHIRA SHAREHOLDERS “WITHHOLD” SUPPORT FROM INCUMBENT DIRECTORS JOSEPH EDELMAN AND JOHN FLUKE ISS Would Have Recommended Shareholders “WITHHOLD” For Full Board Due to Classified Board Structure, Calls Board’

Exhibit 99.1 LEADING PROXY ADVISORY FIRM ISS RECOMMENDS ATHIRA SHAREHOLDERS “WITHHOLD” SUPPORT FROM INCUMBENT DIRECTORS JOSEPH EDELMAN AND JOHN FLUKE ISS Would Have Recommended Shareholders “WITHHOLD” For Full Board Due to Classified Board Structure, Calls Board’s Mechanisms for Management Oversight to be “Lacking”, and Highlights Numerous Other Corporate Governance Missteps Ric Kayne Urges All At

May 5, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d276909ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

May 5, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d300424ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☑ Filed by a Party other than the Registrant ☐ ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as pe

May 5, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

DFAN14A 1 a050522a.htm SCHEDULE 14A INFORMATION UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☐   Preliminary Proxy Statement ☐   Confidential, for Use of the Commission

May 5, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d355581ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

May 4, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a party other than the Registrant ? Check the appropriate box: ????Preliminary Proxy Statement ????Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ??? Defi

May 4, 2022 EX-99.1

RIC KAYNE IDENTIFIES HIGHLY QUALIFIED CEO CANDIDATE FOR ATHIRA Dr. Ronald Krall, Former Chief Medical Officer of GlaxoSmithKline, Willing to Become Athira’s CEO To Maximize Chance of Successful Clinical Trials and Join Board Urges Board to Immediatel

EXHIBIT 99.1 RIC KAYNE IDENTIFIES HIGHLY QUALIFIED CEO CANDIDATE FOR ATHIRA Dr. Ronald Krall, Former Chief Medical Officer of GlaxoSmithKline, Willing to Become Athira’s CEO To Maximize Chance of Successful Clinical Trials and Join Board Urges Board to Immediately Interview Dr. Krall NEW YORK – May 4, 2022 – Richard A. (Ric) Kayne, who together with his affiliates beneficially owns approximately 4

May 2, 2022 EX-99.1

Hi [Shareholder],

Exhibit 99.1 Hi [Shareholder], I hope this note finds you well. As you know, I am trying to drive much needed change at Athira Pharma, Inc. (?Athira?) and I need your help to effect that change before it is too late. Please have a look at the attached presentation and the video we posted to www.SaveAthira.com to learn more about the reasons why I am not sitting idly by. As noted in the proxy state

May 2, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

DFAN14A 1 k52696835a.htm SCHEDULE DFAN14A - DEFINITIVE ADDITIONAL MATERIALS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☐   Preliminary Proxy Statement ☐   Confidential

April 27, 2022 EX-99.2

Transcript of Ric Kayne Proxy Solicitation Video Available at www.SaveAthira.com as of April 27, 2022 Time: 7 minutes, 10 seconds FEMALE VOICEOVER:

EX-99.2 3 k042722c.htm TRANSCRIPT OF VIDEO POSTED TO SAVEATHIRA.COM ON APRIL 27, 2022. Exhibit 99.2 Transcript of Ric Kayne Proxy Solicitation Video Available at www.SaveAthira.com as of April 27, 2022 Time: 7 minutes, 10 seconds FEMALE VOICEOVER: The regeneration of damaged brain tissue. That’s the promise of a potential new drug by Athira Pharma called 1017. It’s why we all invested. A once-in-a

April 27, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a party other than the Registrant ? Check the appropriate box: ????Preliminary Proxy Statement ????Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ??? Defi

April 27, 2022 EX-99.1

RIC KAYNE ISSUES LETTER TO ATHIRA SHAREHOLDERS HIGHLIGHTING WHY IMMEDIATE BOARD CHANGE IS REQUIRED Details Numerous Recent Missteps by Current Athira Board That Have Led to Significant Destruction of Shareholder Value and Outlines the Urgent Need for

Exhibit 99.1 RIC KAYNE ISSUES LETTER TO ATHIRA SHAREHOLDERS HIGHLIGHTING WHY IMMEDIATE BOARD CHANGE IS REQUIRED Details Numerous Recent Missteps by Current Athira Board That Have Led to Significant Destruction of Shareholder Value and Outlines the Urgent Need for Change Releases Video at www.SaveAthira.com Highlighting Why Ric Kayne and George Bickerstaff are Highly Qualified to Restore Board Cred

April 26, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d352494ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

April 26, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d328428ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

April 25, 2022 EX-99.1

DISCLAIMER The views expressed herein and in any other solicitation materials referenced herein and/or attached hereto represent the opinions of Richard A. Kayne and certain of his affiliates (collectively, the “Kayne Entities”) that hold shares of A

EX-99.1 2 a042522b.htm INVESTOR PRESENTATION Exhibit 99.1 Proxy Contest for Board Change at Athira Pharma, Inc. (NASDAQ: ATHA) Immediate Change is Necessary DISCLAIMER The views expressed herein and in any other solicitation materials referenced herein and/or attached hereto represent the opinions of Richard A. Kayne and certain of his affiliates (collectively, the “Kayne Entities”) that hold shar

April 25, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

DFAN14A 1 a042522a.htm SCHEDULE 14A INFORMATION UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☐   Preliminary Proxy Statement ☐   Confidential, for Use of the Commission

April 25, 2022 EX-99.2

RIC KAYNE PUBLISHES INVESTOR PRESENTATION HIGHLIGHTING URGENT NEED FOR CHANGES TO ATHIRA’S BOARD OF DIRECTORS New, Independent, Shareholder-Centric Directors are Needed to Ensure ATH-1017’s Significant Potential is Realized and Reverse Destruction of

Exhibit 99.2 RIC KAYNE PUBLISHES INVESTOR PRESENTATION HIGHLIGHTING URGENT NEED FOR CHANGES TO ATHIRA?S BOARD OF DIRECTORS New, Independent, Shareholder-Centric Directors are Needed to Ensure ATH-1017?s Significant Potential is Realized and Reverse Destruction of Shareholder Value by Athira?s Current Board Launches Campaign Website with Additional Information for Shareholders: www.SaveAthira.com U

April 22, 2022 EX-99.7

BY EMAIL

Exhibit 99.7 BY EMAIL March 25, 2022 Richard A. Kayne 1800 Avenue of the Stars, Third Floor Los Angeles, CA 90067 Dear Ric: I write on behalf of Athira?s board of directors in response to the letter dated March 13, 2022, from your counsel concerning Mark Litton, Ph.D, MBA, the chief executive officer of Athira. Dr. Litton has the full support of Athira?s board of directors. Very truly yours, /s/ K

April 22, 2022 EX-99.6

March 13, 2022

Exhibit 99.6 March 13, 2022 VIA EMAIL Douglas Schnell Michael Nordtvedt Wilson Sonsini Goodrich & Rosati 650 Page Mill Road Palo Alto, CA 94304 Re: Mark Litton Dear Doug and Michael: We write on behalf of Ric Kayne to bring to your attention certain facts and circumstances that we believe warrant the immediate suspension of Mark Litton and an investigation into his fitness to serve as President an

April 22, 2022 EX-99.2

www.SaveAthira.com

Exhibit 99.2 www.SaveAthira.com Disclaimer The views expressed in the solicitation materials referenced herein and/or attached hereto represent the opinions of Richard A. Kayne and certain of his affiliates (collectively, the ?Kayne Entities?) that hold shares of Athira Pharma, Inc. (?Athira? or the ?Company?) and are based on publicly available information with respect to the Company. The Kayne E

April 22, 2022 EX-99.3

March 7, 2022

Exhibit 99.3 March 7, 2022 Kelly Romano, Chair Joseph Edelman Barbara Kosacz James Johnson John J. Fluke, Jr. Grant Pickering Dear independent directors of Athira: By now you are undoubtedly aware that I have submitted a notice nominating two candidates ? myself and George Bickerstaff - to serve on the Athira board at the upcoming annual meeting. I did not take this decision lightly. I believe I s

April 22, 2022 EX-99.5

March 11, 2022

Exhibit 99.5 March 11, 2022 Ric Kayne Willkie Farr & Gallagher LLP Dear Ric: We have reviewed your letter, dated March 7, 2022, and take the issues that you have raised seriously. We appreciate the opportunities we?ve had to discuss your perspectives and share our views with you, and thought it might be helpful here to provide more clarity around the issues and strategies taken by the company. Ath

April 22, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a party other than the Registrant ? Check the appropriate box: ????Preliminary Proxy Statement ????Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ??? Defi

April 22, 2022 EX-99.8

Richard A. Kayne 1800 Avenue of the Stars, Third Floor Los Angeles, CA 90067

Exhibit 99.8 Richard A. Kayne 1800 Avenue of the Stars, Third Floor Los Angeles, CA 90067 April 12, 2022 Via Email Athira Pharma, Inc. Attention: Corporate Secretary 18706 North Creek Parkway, Suite 104 Bothell, Washington 98011 Email: [email protected] Re: Demand to Inspect Certain Books and Records of Athira Pharma, Inc. Pursuant to Section 220 of the General Corporation Law of the Sta

April 22, 2022 EX-99.4

Richard A. Kayne 1800 Avenue of the Stars, Third Floor Los Angeles, CA 90067

Exhibit 99.4 Richard A. Kayne 1800 Avenue of the Stars, Third Floor Los Angeles, CA 90067 March 8, 2022 Via Email Athira Pharma, Inc. Attention: Corporate Secretary 18706 North Creek Parkway, Suite 104 Bothell, Washington 98011 Email: [email protected] Re: Demand to Inspect Certain Books and Records of Athira Pharma, Inc. Pursuant to Section 220 of the General Corporation Law of the Stat

April 20, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d326859ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

April 13, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

DFAN14A 1 a040322a.htm SCHEDULE 14A INFORMATION UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☐   Preliminary Proxy Statement ☐   Confidential, for Use of the Commission

April 13, 2022 EX-99.1

Testimonial of Dr. Joseph Harding

Exhibit 99.1 Testimonial of Dr. Joseph Harding Testimonial in support of Dr. Leen Kawas by Joseph W Harding The Purpose: The purpose of this testimonial is to both rebut claims that question Leen?s integrity and to provide context and clarity regarding to events that are the basis of these claims. Similarly, I wish to counter the notion that that Leen was somehow not integral to the formation and

April 11, 2022 DEFC14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFC14A 1 d340906ddefc14a.htm DEFC14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as pe

April 11, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DFAN14A 1 d480993ddfan14a.htm DFAN14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permi

April 11, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy Statement ? Definitive Additional Materials ? Soliciting Material under ? 240.

April 11, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d341361ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

April 8, 2022 PREC14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

PREC14A 1 d340906dprec14a.htm PREC14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as pe

April 5, 2022 DEFC14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFC14A 1 atha-defc14a20220519.htm DEFC14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (

April 5, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 d346948ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

March 30, 2022 PREC14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

PREC14A 1 d340906dprec14a.htm PREC14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commissi

March 30, 2022 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DFAN14A 1 d329209ddfan14a.htm DFAN14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☐ Filed by a party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commissi

March 30, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

DEFA14A 1 atha-defa14a20220330.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☑ Filed by a Party other than the Registrant □ Check the appropriate box: □ Preliminary Proxy Statement □ Confidential, for Use of the Commission Only (as

March 28, 2022 EX-FILING FEES

Filing Fee Table

EX-FILING FEES 4 atha-exfilingfees137.htm EX-FILING FEES Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Athira Pharma, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered (1)(2) Proposed Maximum Offering Price Per Unit Proposed Maximum Aggregate Offering Price Fe

March 28, 2022 EX-10.28

Change in Control and Severance Agreement between the Registrant and Kevin Church

Exhibit 10.28 ATHIRA PHARMA, INC. CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Change in Control and Severance Agreement (the ?Agreement?) is made by and between Athira Pharma, Inc., a Delaware corporation (the ?Company?), and Kevin Church (?Executive?), effective as of January 31, 2022 (the ?Effective Date?). This Agreement provides certain protections to Executive in connection with an involun

March 28, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39503 Athira Pharma,

March 28, 2022 S-8

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S‑8 REGISTRATION STATEMENT The Securities Act of 1933 ATHIRA PHARMA, INC. (Exact name of Registrant as specified in its charter)

As filed with the Securities and Exchange Commission on March 28, 2022 Registration No.

March 28, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy Statement ? Definitive Additional Materials ? Soliciting Material under ? 240.

March 28, 2022 EX-10.27

First Amendment to Employment Agreement between the Registrant and Hans Moebius, Ph.D.

Exhibit 10.27 18706 NORTH CREEK PARKWAY SUITE 104 BOTHELL, WA 98011 November 17, 2021 Hans Moebius, M.D., Ph. D. Via Email Re: Amendment to Employment Agreement Dear Hans: Reference is made to that certain employment offer letter dated September 13, 2020 (the ?Offer Letter?) between you and Athira Pharma, Inc. (the ?Company?). As discussed, the Compensation Committee of the Board of Directors of t

March 25, 2022 CORRESP

March 25, 2022

Wilson Sonsini Goodrich & Rosati Professional Corporation 701 Fifth Avenue Suite 5100 Seattle, Washington 98104-7036 o: 206.

March 25, 2022 PREC14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

PREC14A 1 atha-prec14a20220429.htm PREC14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14A-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (

March 24, 2022 EX-99.1

Athira Pharma Reports Full Year 2021 Financial Results and Provides Clinical Update On track to report topline data from ACT-AD Phase 2 Alzheimer’s disease study in 2Q22 Expect to complete enrollment in LIFT-AD Phase 3 Alzheimer’s disease study in 3Q

Exhibit 99.1 Athira Pharma Reports Full Year 2021 Financial Results and Provides Clinical Update On track to report topline data from ACT-AD Phase 2 Alzheimer?s disease study in 2Q22 Expect to complete enrollment in LIFT-AD Phase 3 Alzheimer?s disease study in 3Q22 Conference call today at 4:30 pm Eastern time BOTHELL, WA, March 24, 2022 ? Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage

March 24, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 24, 2022 Athira Pharma, Inc.

March 21, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2022 Athira Pharma, Inc.

March 21, 2022 EX-99.1

Athira Pharma Announces Appointment of Dr. Michael A. Panzara to its Board of Directors Industry Veteran Brings More than 20 Years of Experience in CNS Drug Development and Commericalization

Exhibit 99.1 Athira Pharma Announces Appointment of Dr. Michael A. Panzara to its Board of Directors Industry Veteran Brings More than 20 Years of Experience in CNS Drug Development and Commericalization BOTHELL, Wash., March 21, 2022 ? Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and slow neuro

February 14, 2022 SC 13G/A

ATHA / Athira Pharma Inc / VIKING GLOBAL INVESTORS LP - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G INFORMATION TO BE INCLUDED IN STATEMENTS PURSUANT TO RULES 13d- 1(b),(c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934* (Amendment No. 2) Athira Pharma, Inc. (Name of Issuer) Common stock, $0.0001 par value per share (Title of Class of Securities) 04746L104 (CUSIP

February 14, 2022 SC 13G/A

ATHA / Athira Pharma Inc / RTW INVESTMENTS, LP - ATHIRA PHARMA, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* Athira Pharma, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2021 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant

February 14, 2022 SC 13G/A

ATHA / Athira Pharma Inc / Venrock Healthcare Capital Partners II, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursu

February 3, 2022 SC 13G

ATHA / Athira Pharma Inc / FRANKLIN RESOURCES INC Passive Investment

athi21in.htm - Generated by SEC Publisher for SEC Filing CUSIP NO. 04746L104 13G Page 1 of 14 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2021 (Date of

January 31, 2022 EX-10.1

Amended and Restated Change in Control and Severance Agreement between the Registrant and Mark Litton, Ph.D.

EX-10.1 2 d290928dex101.htm EX-10.1 Exhibit 10.1 ATHIRA PHARMA, INC. AMENDED AND RESTATED CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Amended and Restated Change in Control and Severance Agreement (the “Agreement”) is effective as of January 31, 2022 (the “Effective Date”), and amends and restates the Change in Control and Severance Agreement by and between Athira Pharma, Inc., a Delaware corpo

January 31, 2022 EX-99.1

Athira Pharma Announces Appointment of Grant Pickering to its Board of Directors

EX-99.1 4 d290928dex991.htm EX-99.1 Exhibit 99.1 Athira Pharma Announces Appointment of Grant Pickering to its Board of Directors BOTHELL, Wash., January 31, 2022 — Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and stop neurodegeneration, today announced the appointment of Grant Pickering to its

January 31, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 27, 2022 Athira Pharma, Inc.

January 31, 2022 EX-10.2

Outside Director Compensation Policy, as amended

EX-10.2 3 d290928dex102.htm EX-10.2 Exhibit 10.2 ATHIRA PHARMA, INC. OUTSIDE DIRECTOR COMPENSATION POLICY As amended January 27, 2022 Athira Pharma, Inc. (the “Company”) believes that the granting of equity and cash compensation to members of the Company’s Board of Directors (the “Board,” and members of the Board, “Directors”) represents an effective tool to attract, retain and reward Directors wh

November 22, 2021 CORRESP

November 22, 2021

November 22, 2021 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549-3720 Attention: Christine Westbrook Re: Athira Pharma, Inc. Registration Statement on Form S-3 Filed November 15, 2021 (File No. 333-261073) Acceleration Request Requested Date: November 24, 2021 Requested Time: 4:00 P.M. Eastern Stan

November 15, 2021 EX-4.3

Form of Indenture

Exhibit 4.3 ATHIRA PHARMA, INC. INDENTURE Dated as of [ ], 202 [] Trustee TABLE OF CONTENTS Page ARTICLE I DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1 Definitions 1 Section 1.2 Other Definitions 4 Section 1.3 Incorporation by Reference of Trust Indenture Act 5 Section 1.4 Rules of Construction 5 ARTICLE II THE SECURITIES 6 Section 2.1 Issuable in Series 6 Section 2.2 Establishment of

November 15, 2021 S-3

As filed with the Securities and Exchange Commission on November 15, 2021

As filed with the Securities and Exchange Commission on November 15, 2021 Registration No.

November 10, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2021 Athira Pharma, Inc.

November 10, 2021 EX-99.1

Athira Pharma Reports Third Quarter 2021 Financial Results and Business Update – Completed enrollment of ACT-AD trial with topline data expected in the first half of 2022; LIFT-AD is actively recruiting with topline data expected by the end of 2022 –

Exhibit 99.1 Athira Pharma Reports Third Quarter 2021 Financial Results and Business Update ? Completed enrollment of ACT-AD trial with topline data expected in the first half of 2022; LIFT-AD is actively recruiting with topline data expected by the end of 2022 ? ? Presented program updates and baseline data from ATH-1017?s ongoing Phase 2 and Phase 2/3 clinical trials at the 2021 CTAD conference

November 10, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

October 21, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 18, 2021 Athira Pharma, Inc.

October 21, 2021 EX-99.1

Athira Pharma Announces Leadership Changes; Mark Litton, Ph.D., M.B.A. Named President and Chief Executive Officer; Rachel Lenington, M.B.A. Named Chief Operating Officer

Exhibit 99.1 Athira Pharma Announces Leadership Changes; Mark Litton, Ph.D., M.B.A. Named President and Chief Executive Officer; Rachel Lenington, M.B.A. Named Chief Operating Officer ? Special Committee of the Board of Directors has concluded its investigation of Dr. Leen Kawas?s Doctoral Research ? Conference call to be held October 21, 2021 at 4:30 pm ET BOTHELL, WA, October 21, 2021 ? Athira P

October 21, 2021 EX-10.1

Separation Agreement dated October 18, 2021 between Leen Kawas and Athira

Exhibit 10.1 SEPARATION AGREEMENT AND RELEASE This Separation Agreement and Release (?Agreement?) is made by and between Leen Kawas (?Employee?) and Athira Pharma, Inc. (the ?Company?) (collectively referred to as the ?Parties? or individually referred to as a ?Party?). WHEREAS, Employee was employed at-will by the Company pursuant to that certain Confirmatory Employment Letter between the Parties

August 16, 2021 EX-10.2

Change in Control and Severance Agreement between the Registrant and Rachel Lenington

Exhibit 10.2 ATHIRA PHARMA, INC. CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Change in Control and Severance Agreement (the ?Agreement?) is made by and between Athira Pharma, Inc., a Delaware corporation (the ?Company?), and Rachel Lenington (?Executive?), effective as of June 14, 2021 (the ?Effective Date?). This Agreement provides certain protections to Executive in connection with an involun

August 16, 2021 EX-10.3

Employment Offer Letter between the Registrant and Mark Worthington

Exhibit 10.3 18706 North Creek Parkway Suite 104 Bothell, Washington 98011 May 10, 2021 Mark Worthington Via Email Re: Offer Letter Dear Mark: I am pleased to offer you a position with Athira Pharma, Inc. (the ?Company?) in accordance with the terms of this offer letter (the ?Agreement?). 1.Title; Position. You will serve as the Company?s General Counsel. You will report to the Company?s Chief Exe

August 16, 2021 EX-10.5

First Amendment to Lease by and between the Registrant and Nitrogen Propco 2020, L.P., as successor-in-interest to North Creek Parkway Center Investors, L.P., dated June 28, 2021

Exhibit 10.5 FIRST AMENDMENT TO LEASE This First Amendment to Lease (this ?First Amendment?) is dated as of June 28, 2021, and is by and between NITROGEN PROPCO 2020, L.P., a Delaware limited partnership (?Landlord?), and ATHIRA PHARMA, INC., a Delaware corporation (?Tenant?). r e c i t a l s : A.Landlord (as successor-in-interest to North Creek Parkway Center Investors, LP, a California limited p

August 16, 2021 EX-99.1

Athira Pharma Reports Second Quarter 2021 Financial Results and Business Update -Initiated open label extension for LIFT-AD and ACT-AD trials of ATH-1017 allowing for an additional six months of treatment - ACT-AD and LIFT-AD are actively recruiting;

Exhibit 99.1 Athira Pharma Reports Second Quarter 2021 Financial Results and Business Update -Initiated open label extension for LIFT-AD and ACT-AD trials of ATH-1017 allowing for an additional six months of treatment - ACT-AD and LIFT-AD are actively recruiting; topline data of ACT-AD are targeted by first half 2022 and topline data from LIFT-AD are targeted by end of 2022 BOTHELL, WA, August 16,

August 16, 2021 EX-10.1

Employment Offer Letter between the Registrant and Rachel Lenington

Exhibit 10.1 18706 North Creek Parkway Suite 104 Bothell, Washington 98011 April 27, 2021 Rachel Lenington Via Email Re: Offer Letter Dear Rachel: I am pleased to offer you a position with Athira Pharma, Inc. (the ?Company?) in accordance with the terms of this offer letter (the ?Agreement?). 1.Title; Position. You will serve as the Company?s Chief Technology Officer and Head of Product Developmen

August 16, 2021 EX-10.4

Change in Control and Severance Agreement between the Registrant and Mark Worthington

Exhibit 10.4 ATHIRA PHARMA, INC. CHANGE IN CONTROL AND SEVERANCE AGREEMENT This Change in Control and Severance Agreement (the ?Agreement?) is made by and between Athira Pharma, Inc., a Delaware corporation (the ?Company?), and Mark Worthington (?Executive?), effective as of June 1, 2021 (the ?Effective Date?). This Agreement provides certain protections to Executive in connection with an involunt

August 16, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

August 16, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 16, 2021 Athira Pharma, Inc.

August 9, 2021 EX-99.1

Athira Pharma Mourns the Loss of Chair of Board of Directors, Tadataka Yamada, M.D.

Exhibit 99.1 Athira Pharma Mourns the Loss of Chair of Board of Directors, Tadataka Yamada, M.D. BOTHELL, WA, August 5, 2021 ? Athira Pharma, Inc. (NASDAQ: ATHA) (?Athira?), a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and stop neurodegeneration, mourns the passing of Tadataka ?Tachi? Yamada, M.D., the chair of the company?s board

August 9, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 4, 2021 Athira Pharma, Inc.

June 18, 2021 EX-99.1

Athira Pharma Chief Operating Officer, Mark Litton, Assumes Day-to-Day Leadership Responsibilities of Company Leen Kawas Placed on Temporary Leave Pending Board Review of Actions Stemming from Doctoral Research while at Washington State University

Exhibit 99.1 Athira Pharma Chief Operating Officer, Mark Litton, Assumes Day-to-Day Leadership Responsibilities of Company Leen Kawas Placed on Temporary Leave Pending Board Review of Actions Stemming from Doctoral Research while at Washington State University BOTHELL, WASHINGTON, June 17, 2021 ? Athira Pharma, Inc. (NASDAQ: ATHA) (?Athira?), a late clinical-stage biopharmaceutical company focused

June 18, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 16, 2021 Athira Pharma, Inc.

June 1, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 27, 2021 Athira Pharma, Inc.

May 13, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

May 13, 2021 EX-99.1

Athira Pharma Reports First Quarter 2021 Financial Results and Provides Business Highlights -Phase 2 trial initiation for Parkinson’s disease dementia program and IND submission for neuropsychiatric program planned by end of 2021- -Hosted educational

EX-99.1 2 atha-ex99167.htm EX-99.1 Exhibit 99.1 Athira Pharma Reports First Quarter 2021 Financial Results and Provides Business Highlights -Phase 2 trial initiation for Parkinson’s disease dementia program and IND submission for neuropsychiatric program planned by end of 2021- -Hosted educational webinar on targeting HGF/MET featuring leading neurologist Marwan Sabbagh, M.D- - Raised $103.5M in f

May 13, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2021 Athira Pharma, Inc.

April 16, 2021 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a?6(e)(2)) ? Definitive Proxy State

April 16, 2021 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Filed by a party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a?6(e)(2)) ? Definitive Proxy State

March 26, 2021 S-8

- S-8

As filed with the Securities and Exchange Commission on March 25, 2021 Registration No.

March 25, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 25, 2021 Athira Pharma, Inc.

March 25, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39503 Athira Pharma,

March 25, 2021 EX-4.3

Description of Capital Stock

Exhibit 4.3 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 As of December 31, 2020, we had one class of securities, our common stock, registered under Section 12 of the Securities Exchange Act of 1934, as amended. These securities are listed on the Nasdaq Global Select Market under the symbol ?ATHA.? Our authorized capital stock

March 25, 2021 EX-99.1

Athira Pharma Reports Fourth Quarter and Full Year 2020 Financial Results and Provides Business Highlights

EX-99.1 2 atha-ex99119.htm EX-99.1 Exhibit 99.1 Athira Pharma Reports Fourth Quarter and Full Year 2020 Financial Results and Provides Business Highlights - LIFT-AD and ACT-AD studies evaluating ATH-1017, a once-daily investigational drug for the treatment of mild-to-moderate Alzheimer’s disease, actively enrolling patients – - IND submissions planned for Parkinson’s disease dementia program in 1H

March 8, 2021 EX-99.1

Athira Pharma Announces Appointment of Barbara Kosacz to its Board of Directors

Athira Pharma Announces Appointment of Barbara Kosacz to its Board of Directors BOTHELL, WASHINGTON, March 8, 2021 — Athira Pharma, Inc.

March 8, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 4, 2021 Athira Pharma, Inc.

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) (C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursu

February 16, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Athira Pharma, Inc. (Name of Issuer) Common stock, par value $0.0001 per share (Title of Class of Securit

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Athira Pharma, Inc. (Name of Issuer) Common stock, par value $0.0001 per share (Title of Class of Securities) 04746L104 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rul

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A INFORMATION TO BE INCLUDED IN STATEMENTS PURSUANT TO RULES 13d- 1(b),(c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934* (Amendment No. 1) Athira Pharma, Inc. (Name of Issuer) Common stock, $0.0001 par value per share (Title of Class of Securities) 04746L104 (CUS

February 12, 2021 EX-1

Joint Filing Statement Pursuant to Rule 13d-1(k)(1)

Exhibit 1 Joint Filing Statement Pursuant to Rule 13d-1(k)(1) The undersigned hereby consent and agree to the joint filing of Schedule 13G Amendment No.

February 12, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Athira Pharma, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) (CUSIP Number) December 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

February 8, 2021 SC 13D

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment ___)* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L

SC 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment )* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L 104 (CUSIP Number) Alexander Rakitin Perceptive Advisors LLC 51 Astor Place, 10th Floor New York, NY 10003 (646) 205-5340 (Name, Address and Tele

February 8, 2021 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 d339235dex991.htm EX-99.1 Exhibit 1 JOINT FILING AGREEMENT The persons below hereby agree that the Schedule 13D to which this agreement is attached as an exhibit, as well as all future amendments to such Schedule 13D, shall be filed jointly on behalf of each of them. This agreement is intended to satisfy the requirements of Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934.

January 21, 2021 424B4

4,000,000 Shares Common Stock

Filed Pursuant to Rule 424(b)(4) Registration No. 333-252192 4,000,000 Shares Common Stock We are offering 4,000,000 shares of common stock. Our common stock is listed on the Nasdaq Global Select Market under the symbol “ATHA.” On January 20, 2021, the last reported sale price of our common stock on the Nasdaq Global Select Market was $24.32 per share. We are an “emerging growth company” as define

January 19, 2021 S-1

As filed with the Securities and Exchange Commission on January 19, 2021.

As filed with the Securities and Exchange Commission on January 19, 2021. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S‑1 REGISTRATION STATEMENT Under The Securities Act of 1933 ATHIRA PHARMA, INC. (Exact name of Registrant as specified in its charter) Delaware 2836 45-3368487 (State or other jurisdiction of incorporation or organization) (Pri

January 19, 2021 EX-1.1

Form of Underwriting Agreement

Exhibit 1.1 Athira Pharma, Inc. Common Stock, par value $0.0001 per share Underwriting Agreement [●], 2021 Goldman Sachs & Co. LLC Jefferies LLC As representatives (the “Representatives”) of the several Underwriters named in Schedule I hereto c/o Goldman Sachs & Co. LLC 200 West Street New York, New York 10282 c/o Jefferies LLC 520 Madison Avenue New York, New York 10022 Ladies and Gentlemen: Athi

January 15, 2021 CORRESP

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January 15, 2021 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549-3720 Attention:David Gessert Re: Athira Pharma, Inc. Draft Registration Statement on Form S-1 Submitted January 6, 2021 Registration Statement on Form S-1 to be filed on January 19, 2021 (File No. 333- ) Acceleration Request Requested

January 15, 2021 CORRESP

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January 15, 2021 United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.

January 11, 2021 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 8, 2021 Athira Pharma, Inc.

January 11, 2021 EX-99.1

Overview of Athira Pharma Pipeline focused on regeneration of neuronal damage in CNS and peripheral diseases to restore function ATH-1017 LEAD INDICATION: Alzheimer’s disease POTENTIAL FOLLOW-ON INDICATIONS: Parkinson’s dementia, ALS, MS, neuropathy,

Restoring Lives by Advancing Bold Therapies Corporate Presentation, January 2021 © Athira Pharma, Inc.

January 6, 2021 DRS

Confidential Treatment Requested by Athira Pharma, Inc. Pursuant to 17 C.F.R. Section 200.83 As confidentially submitted with the Securities and Exchange Commission on January 6, 2021. This draft registration statement has not been publicly filed wit

Confidential Treatment Requested by Athira Pharma, Inc. Pursuant to 17 C.F.R. Section 200.83 As confidentially submitted with the Securities and Exchange Commission on January 6, 2021. This draft registration statement has not been publicly filed with the Securities and Exchange Commission and all information herein remains strictly confidential. Registration No. 333- UNITED STATES SECURITIES AND

December 14, 2020 EX-99.1

Athira Pharma Announces Appointment of Kelly A. Romano to its Board of Directors

Exhibit 99.1 Athira Pharma Announces Appointment of Kelly A. Romano to its Board of Directors SEATTLE, Dec. 14, 2020 — Athira Pharma, Inc. (NASDAQ: ATHA), a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and stop neurodegeneration, today announced the appointment of Kelly A. Romano to its Board of Directors. Ms. Romano is the Founder

December 14, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 11, 2020 Athira Pharma, Inc.

November 16, 2020 SC 13G

ATHA / Athira Pharma, Inc. / Venrock Healthcare Capital Partners II, L.P. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* Athira Pharma, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 04746L104 (CUSIP Number) November 6, 2020 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursuant

November 12, 2020 EX-3.1

Amended and Restated Certificate of Incorporation of the Company

Exhibit 3.1 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF ATHIRA PHARMA, INC. a Delaware corporation Athira Pharma, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), does hereby certify as follows: A.The Company was originally incorporated under the name of M3 Biotechnology, Inc., and the original Certificate of Incorporation of the Company

November 12, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39503 Athira Pharma, Inc.

November 12, 2020 EX-3.2

Amended and Restated Bylaws of the Company

Exhibit 3.2 AMENDED AND RESTATED BYLAWS OF ATHIRA PHARMA, INC. (initially adopted on October 27, 2015) (as amended on September 22, 2020) TABLE OF CONTENTS Page ARTICLE I - CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II - MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 ADVANCE NOTICE PROCEDURES 2 2.5 NOTICE OF STOCKHOLDE

November 12, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2020 Athira Pharma, Inc.

November 12, 2020 EX-99.1

Athira Pharma Reports Third Quarter 2020 Financial Results and Provides Business Highlights - LIFT-AD clinical trial evaluating ATH-1017, a once-daily investigational drug for the treatment of mild-to-moderate Alzheimer’s disease, actively enrolling

Exhibit 99.1 Athira Pharma Reports Third Quarter 2020 Financial Results and Provides Business Highlights - LIFT-AD clinical trial evaluating ATH-1017, a once-daily investigational drug for the treatment of mild-to-moderate Alzheimer’s disease, actively enrolling - Strong cash, cash equivalents and investments balance of $259.9 million as of September 30, 2020 SEATTLE, Nov. 12, 2020 — Athira Pharma

September 28, 2020 SC 13G

ATHA / Athira Pharma, Inc. / RTW INVESTMENTS, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

September 28, 2020 EX-1

Joint Filing Statement Pursuant to Rule 13d-1(k)(1)

Exhibit 1 Joint Filing Statement Pursuant to Rule 13d-1(k)(1) The undersigned hereby consent and agree to the joint filing of Schedule 13G under the Securities Exchange Act of 1934, as amended, with respect to the Common Stock of Athira Pharma, Inc.

September 28, 2020 SC 13G

ATHA / Athira Pharma, Inc. / VIKING GLOBAL INVESTORS LP - ACQUISITION OF BENEFICIAL OWNERSHIP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G INFORMATION TO BE INCLUDED IN STATEMENTS PURSUANT TO RULES 13d-1(b),(c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934* Athira Pharma, Inc. (Name of Issuer) Common stock, $0.0001 par value per share (Title of Class of Securities) 04746L104 (CUSIP Number) September

September 18, 2020 S-8

- S-8

As filed with the Securities and Exchange Commission on September 18, 2020 Registration No.

September 18, 2020 424B4

12,000,000 Shares Common Stock

Filed Pursuant to Rule 424(b)(4) Registration No. 333-248428 and Registration No. 333-248878 12,000,000 Shares Common Stock This is the initial public offering of shares of common stock of Athira Pharma, Inc. We are offering 12,000,000 shares of common stock. Prior to this offering, there has been no public market for our common stock. The initial public offering price is $17.00 per share. We have

September 17, 2020 CORRESP

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Wilson Sonsini Goodrich & Rosati Professional Corporation 650 Page Mill Road Palo Alto, California 94304-1050 o: 650.

September 17, 2020 S-1MEF

- S-1MEF

As filed with the Securities and Exchange Commission on September 17, 2020 Registration No.

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