CRBP / Corbus Pharmaceuticals Holdings, Inc. - Pemfailan SEC, Laporan Tahunan, Penyata Proksi

Corbus Pharmaceuticals Holdings, Inc.
US ˙ NasdaqCM ˙ US21833P3010

Statistik Asas
LEI 529900MX6XCNZC7MM155
CIK 1595097
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Corbus Pharmaceuticals Holdings, Inc.
SEC Filings (Chronological Order)
Halaman ini menyediakan senarai kronologi lengkap bagi Pemfailan SEC, tidak termasuk pemfailan pemilikan yang kami sediakan di tempat lain.
August 5, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

August 5, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2025 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

August 5, 2025 EX-99.1

Corbus Pharmaceuticals Reports Second Quarter 2025 Financial Results and Provides a Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports Second Quarter 2025 Financial Results and Provides a Corporate Update • Phase 1/2 dose expansion data for Nectin-4 targeting ADC CRB-701 to be presented at ESMO 2025 • Initiated 7-day MAD portion of Phase 1 study for obesity drug CRB-913 • All three clinical programs (CRB-701, CRB-913, CRB-601) on track for data readouts in the second half of 2025 Norwoo

May 19, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2025 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 6, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 6, 2025 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation) (

May 6, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

May 6, 2025 EX-99.1

Corbus Pharmaceuticals Reports First Quarter 2025 Financial Results and Provides a Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports First Quarter 2025 Financial Results and Provides a Corporate Update • Dose optimization and RP2D determination on schedule for completion in Q4 2025 for the Nectin-4 ADC CRB-701 in HNSCC, cervical and mUC tumors • SAD/MAD study on schedule for completion in Q3 2025 for the anti-obesity CB1 inverse agonist CRB-913 • Dose escalation study on schedule for

April 1, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

April 1, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Definitive Proxy State

March 21, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2025 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

March 18, 2025 EX-10.1

Service Agreement between Corbus International Limited and Ian Hodgson, effective as of March 15, 2025.

Exhibit 10.1 This Agreement is made on March 15, 2025 Between: (1) Corbus International Limited (company number: 11195935) whose registered office is at 5 New Street Square, London, EC4A 3TW (Company, we, us); and (2) Ian Hodgson of , , (You, your) It is agreed as follows: 1. Definitions and interpretation 1.1 This Agreement means this agreement and any schedules to this agreement which form part

March 18, 2025 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 13, 2025 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

March 11, 2025 EX-99.1

Corbus Pharmaceuticals Reports Q4 and 2024 Financial Results and Provides a Corporate Update

Appendix 99.1 Corbus Pharmaceuticals Reports Q4 and 2024 Financial Results and Provides a Corporate Update • CRB-701 Nectin-4 targeting ADC demonstrates encouraging results in Phase 1 Western study • Fast Track Designation granted by FDA for CRB-701 to treat metastatic cervical cancer • CRB 913 SAD/MAD obesity study expected to start in March 2025 • $149m of cash & investments as of December 31,20

March 11, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO . Commission File Number 001-37348 Corbus Pharma

March 11, 2025 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 11, 2025 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

March 11, 2025 EX-21.1

List of Subsidiaries of the Company.*

Exhibit 21.1 SUBSIDIARIES (WHOLLY-OWNED) OF CORBUS PHARMACEUTICALS HOLDINGS, INC. Name of Organization Jurisdiction Corbus Pharmaceuticals, Inc. Delaware Corbus International Limited United Kingdom Corbus Pharmaceuticals Australia Pty Ltd Australia

March 11, 2025 EX-19.1

Insider Trading Policy. *

Exhibit 19.1 CORBUS PHARMACEUTICALS HOLDINGS, INC. STATEMENT OF COMPANY POLICY ON INSIDER TRADING AND POLICY REGARDING SPECIAL TRADING PROCEDURES* Two copies of this Statement of Company Policy on Insider Trading and Policy Regarding Special Trading Procedures (collectively, this “Policy”) are being provided to you. You should read this Policy, address questions to Sean Moran, our Chief Financial

February 14, 2025 EX-99.A

EXHIBIT A: Joint Filing Agreement

EX-99.A 2 ss4343261ex99a.htm JOINT FILING AGREEMENT CUSIP No. 21833P301 SCHEDULE 13G Page 9 of 9 Pages EXHIBIT A: Joint Filing Agreement The undersigned hereby agree that this Amendment No. 1 to the Statement on Schedule 13G, dated December 31, 2024 (this “Schedule 13G”), with respect to the Common Stock, par value $0.0001 per share, of Corbus Pharmaceuticals Holdings, Inc. is filed on behalf of e

February 14, 2025 EX-99.1

CRB-701 (SYS6002) A Next Generation Nectin-4 Targeting ADC Demonstrates Encouraging Safety and Broader Efficacy in Phase 1 Study in the US and UK Presented at ASCO-GU 2025

Exhibit 99.1 CRB-701 (SYS6002) A Next Generation Nectin-4 Targeting ADC Demonstrates Encouraging Safety and Broader Efficacy in Phase 1 Study in the US and UK Presented at ASCO-GU 2025 • Study mirrored 4 highest doses used in China dose escalation study presented at ASCO 2024 • Safety, tolerability and PK comparable to China dataset with no DLTs observed in either study • Low levels of peripheral

February 14, 2025 EX-99.2

This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including t

Connecting Innovation to Purpose NASDAQ: CRBP Corporate Presentation February 14, 2025 Exhibit 99.

February 14, 2025 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 14, 2025 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

December 3, 2024 EX-99.1

FDA Grants Fast Track Designation to CRB-701 for the Treatment of Relapsed or Refractory Metastatic Cervical Cancer

Exhibit 99.1 FDA Grants Fast Track Designation to CRB-701 for the Treatment of Relapsed or Refractory Metastatic Cervical Cancer Norwood, MA, December 3, 2024 (GLOBE NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”), an oncology and obesity company with a diversified portfolio, announced today that the U.S. Food and Drug Administration (FDA) has granted F

December 3, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 03, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

November 15, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 15, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

November 14, 2024 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings, Inc. / Cormorant Asset Management, LP Passive Investment

SC 13G/A 1 cormorant-crbp093024a2.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 21833P301 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropr

November 14, 2024 SC 13G

CRBP / Corbus Pharmaceuticals Holdings, Inc. / ORBIMED ADVISORS LLC - SCHEDULE 13G Passive Investment

SC 13G 1 ss4113323sc13g.htm SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check

November 14, 2024 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings, Inc. / TANG CAPITAL MANAGEMENT LLC - AMENDMENT NO. 1 Passive Investment

SC 13G/A 1 crbp1015240sc13ga1.htm AMENDMENT NO. 1 Securities and Exchange Commission Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of This S

November 14, 2024 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings, Inc. / K2 HealthVentures Equity Trust LLC - SC 13G/A Passive Investment

SC 13G/A 1 ef20038297sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value, $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of

November 14, 2024 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings, Inc. / Point72 Asset Management, L.P. - CORBUS PHARMACEUTICALS HOLDINGS, INC. Passive Investment

SC 13G/A 1 p24-3154sc13ga.htm CORBUS PHARMACEUTICALS HOLDINGS, INC. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) September 30, 2024 (Date of Event Which Requi

November 12, 2024 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings, Inc. / Adage Capital Management, L.P. - CORBUS PHARMACEUTICALS HOLDINGS, INC. Passive Investment

SC 13G/A 1 p24-3024sc13ga.htm CORBUS PHARMACEUTICALS HOLDINGS, INC. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) September 30, 2024** (Date of Event Which Req

November 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

November 7, 2024 EX-99.1

Corbus Pharmaceuticals Reports 3rd Quarter 2024 Financial Results and Provides a Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports 3rd Quarter 2024 Financial Results and Provides a Corporate Update • Completed Enrollment of Dose Escalation Part of Phase 1 Clinical Trial of its Next-Generation Nectin-4 Targeting ADC (CRB-701) - First data expected to be presented in Q1 2025 • Presented New CRB-913 Pre-Clinical Data at Obesity Week 2024 - Phase 1 Trial Expected to Commence in Q1 2025

November 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 07, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

November 7, 2024 EX-99.2

This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including t

Connecting Innovation to Purpose NASDAQ: CRBP Corporate Presentation November 7, 2024 Exhibit 99.

November 4, 2024 EX-99.1

Corbus Pharmaceuticals Presents New CRB-913 Pre-Clinical Data At Obesity Week 2024

Exhibit 99.1 Corbus Pharmaceuticals Presents New CRB-913 Pre-Clinical Data At Obesity Week 2024 • CRB-913 brain levels are 15-fold lower than monlunabant in lean mice • Dose-response demonstrated for a range of 5 to 80 mg/kg/day achieving up to 38% weight loss in DIO mice • Semaglutide treatment followed by its replacement with CRB-913 demonstrated continued weight loss in DIO mice • Switching fro

November 4, 2024 EX-99.2

This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including t

Connecting Innovation to Purpose NASDAQ: CRBP Corporate Presentation November 4, 2024 Exhibit 99.

November 4, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 04, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

October 15, 2024 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings, Inc. / MILLENNIUM MANAGEMENT LLC Passive Investment

SC 13G/A 1 CRBPSC13GA1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (AMENDMENT NO. 1) CORBUS PHARMACEUTICALS HOLDINGS, INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.0001 PER SHARE (Title of Class of Securities) 21833P301 (CUSIP Number) SEPTEMBER 30, 2024 (Date of event which requires filing of this statement)

October 11, 2024 SC 13G

CRBP / Corbus Pharmaceuticals Holdings, Inc. / Octagon Capital Advisors LP Passive Investment

SC 13G 1 crbp1011241sc13g.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 21833P301 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of This Statement) Check t

September 3, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 29, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporatio

August 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 15, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporatio

August 20, 2024 EX-99.1

Corbus Pharmaceuticals Strengthens Board of Directors with Appointment of Winston Kung

Exhibit 99.1 Corbus Pharmaceuticals Strengthens Board of Directors with Appointment of Winston Kung Norwood, MA, August 20, 2024 (GLOBE NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”), today announced the appointment of Winston Kung to its Board of Directors. The appointment was effective as of August 16, 2024. Mr. Kung will also chair the Audit Committ

August 6, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

August 6, 2024 EX-99.1

Corbus Pharmaceuticals Reports Second Quarter 2024 Financial Results and Provides a Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports Second Quarter 2024 Financial Results and Provides a Corporate Update • Clinical update presented at ASCO 2024 for CRB-701 showed continued differentiated safety and encouraging efficacy in patients with metastatic urothelial cancer or cervical cancer • CRB-701 Phase 1 dose escalation underway in USA and Europe for patients with metastatic urothelial can

August 6, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 06, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporatio

August 6, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 06, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporatio

August 6, 2024 EX-99.1

This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including t

Connecting Innovation to Purpose NASDAQ: CRBP Corporate Presentation August 6, 2024 Exhibit 99.

June 17, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 14, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

June 3, 2024 EX-99.2

This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including t

Connecting Innovation to Purpose NASDAQ: CRBP Corporate Presentation June 1, 2024 Exhibit 99.

June 3, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 01, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

June 3, 2024 EX-99.1

SYS6002 (CRB-701) A Next Generation Nectin-4 Targeting Antibody Drug Conjugate Continues to Demonstrate Encouraging Safety and Efficacy Observed in Patients with Nectin-4 Positive Tumors in a Clinical Update Presented at ASCO 2024

Exhibit 99.1 SYS6002 (CRB-701) A Next Generation Nectin-4 Targeting Antibody Drug Conjugate Continues to Demonstrate Encouraging Safety and Efficacy Observed in Patients with Nectin-4 Positive Tumors in a Clinical Update Presented at ASCO 2024 • An additional 19 patients have been enrolled since January 2024 bringing the total to 37 of whom 25 were evaluable for efficacy • SYS6002 (CRB-701) demons

May 31, 2024 EX-10.1

CORBUS PHARMACEUTICALS HOLDINGS, INC. 2024 EQUITY COMPENSATION PLAN

Exhibit 10.1 CORBUS PHARMACEUTICALS HOLDINGS, INC. 2024 EQUITY COMPENSATION PLAN 1. Establishment and Purpose 1.1 The purpose of the Corbus Pharmaceuticals Holdings, Inc. 2024 Equity Compensation Plan (the “Plan”) is to provide a means whereby eligible employees, officers, non-employee directors and other individual service providers develop a sense of proprietorship and personal involvement in th

May 31, 2024 S-8

As filed with the Securities and Exchange Commission on May 31, 2024

As filed with the Securities and Exchange Commission on May 31, 2024 Registration No.

May 31, 2024 EX-FILING FEES

Calculation of Filing Fee Table.*

Exhibit 107 CALCULATION OF FILING FEE TABLE Form S-8 (Form Type) Corbus Pharmaceuticals Holdings, Inc.

May 20, 2024 EX-10.2

Form of Incentive Stock Option Grant Agreement.

EXHIBIT 10.2 FORM OF INCENTIVE STOCK OPTION GRANT AGREEMENT CORBUS PHARMACEUTICALS HOLDINGS, INC. This Stock Option Grant Agreement (the “Grant Agreement”) is made and entered into effective on the Date of Grant set forth in Exhibit A (the “Date of Grant”) by and between Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation (the “Company”), and the individual named in Exhibit A hereto (the

May 20, 2024 EX-10.3

Form of Non-Statutory Stock Option Grant Agreement (incorporated by reference to Exhibit 10.3 of the Company’s Current Report on Form 8-K, filed with the SEC on May 20, 2024).†

EXHIBIT 10.3 FORM OF NONQUALIFIED STOCK OPTION GRANT AGREEMENT CORBUS PHARMACEUTICALS HOLDINGS, INC. This Stock Option Grant Agreement (the “Grant Agreement”) is made and entered into effective on the Date of Grant set forth in Exhibit A (the “Date of Grant”) by and between Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation (the “Company”), and the individual named in Exhibit A hereto (

May 20, 2024 EX-10.1

Corbus Pharmaceuticals Holdings, Inc. 2024 Equity Compensation Plan.

EXHIBIT 10.1 CORBUS PHARMACEUTICALS HOLDINGS, INC. 2024 EQUITY COMPENSATION PLAN 1. Establishment and Purpose 1.1 The purpose of the Corbus Pharmaceuticals Holdings, Inc. 2024 Equity Compensation Plan (the “Plan”) is to provide a means whereby eligible employees, officers, non-employee directors and other individual service providers develop a sense of proprietorship and personal involvement in th

May 20, 2024 EX-10.5

Form of Restricted Stock Unit Award Agreement (incorporated by reference to Exhibit 10.5 of the Company’s Current Report on Form 8-K, filed with the SEC on May 20, 2024).†

EXHIBIT 10.5 FORM OF RESTRICTED STOCK UNIT AWARD AGREEMENT CORBUS PHARMACEUTICALS HOLDINGS, INC. 2024 EQUITY INCENTIVE PLAN This Restricted Stock Unit Award Agreement (the “Agreement” or “Award Agreement”), dated as of the “Award Date” set forth in the attached Exhibit A, is entered into between Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation (the “Company”), and the individual named

May 20, 2024 EX-10.4

Form of Restricted Stock Award Agreement (incorporated by reference to Exhibit 10.4 of the Company’s Current Report on Form 8-K, filed with the SEC on May 20, 2024).†

EXHIBIT 10.4 FORM OF Restricted Stock Agreement CORBUS PHARMACEUTICALS HOLDINGS, INC. This Restricted Stock Award Agreement (the “Agreement”), dated as of the “Award Date” set forth in the attached Exhibit A (the “Award Date”), is entered into between Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation (the “Company”), and the individual named in Exhibit A hereto (the “Awardee”). WHEREAS

May 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 09, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

May 7, 2024 EX-99.1

Corbus Pharmaceuticals Reports First Quarter 2024 Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports First Quarter 2024 Financial Results and Provides Corporate Update • Phase 1 data for CRB-701 (SYS6002) to be presented at ASCO Annual Meeting on June 1, 2024 • $116M of capital raised in Q1 2024 extending cash runway through Q1 2027 • Appointed Dr. Dominic Smethurst as Chief Medical Officer Norwood, MA, May 7, 2024 (GLOBE NEWSWIRE) - Corbus Pharmaceutic

May 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 07, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

April 10, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

April 10, 2024 EX-10.1

Form of Fifth Amended and Restated Employment Agreement between Corbus Pharmaceuticals Holdings, Inc. and Yuval Cohen.

Exhibit 10.1 FIFTH AMENDED AND RESTATED EMPLOYMENT AGREEMENT This Fifth Amended and Restated Employment Agreement (this “Agreement”), effective as of April 10, 2024 (the “Effective Date”), is between Corbus Pharmaceuticals Holdings, Inc. (the “Company”) and Yuval Cohen (the “Executive”). WITNESSETH: WHEREAS, the Executive has been employed by the Company as its Chief Executive Officer pursuant to

April 10, 2024 EX-10.2

Form of Sixth Amended and Restated Employment Agreement between Corbus Pharmaceuticals Holdings, Inc. and Sean Moran.

Exhibit 10.2 SIXTH AMENDED AND RESTATED EMPLOYMENT AGREEMENT This SIXTH AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this “Agreement”), effective as of April 10, 2024 (the “Effective Date”), is between Corbus Pharmaceuticals Holdings, Inc. (the “Company”) and Sean Moran (the “Executive”). WITNESSETH: WHEREAS, the Executive has been employed by the Company as its Chief Financial Officer pursuant to t

April 10, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 10, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

April 2, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

April 2, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Definitive Proxy State

March 22, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

March 20, 2024 424B3

Up to $150,000,000 Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-277888 PROSPECTUS Up to $150,000,000 Common Stock We have entered into an Open Market Sale Agreement, or sale agreement, with Jefferies LLC relating to shares of our common stock offered by this prospectus. In accordance with the terms of the sale agreement, we may offer and sell shares of our common stock having an aggregate offering price of

March 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

March 20, 2024 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO . Commission File Number 001

March 18, 2024 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings, Inc. / Cormorant Asset Management, LP - AMENDMENT NO. 1 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 21833P301 (CUSIP Number) March 8, 2024 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to

March 18, 2024 CORRESP

Corbus Pharmaceuticals Holdings, Inc. 500 River Ridge Drive Norwood, MA 02062

Corbus Pharmaceuticals Holdings, Inc. 500 River Ridge Drive Norwood, MA 02062 March 18, 2024 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Corbus Pharmaceuticals Holdings, Inc. (the “Company”) Registration Statement on Form S-3 (File No. 333-277888) Ladies and Gentlemen: In accordance with Rule 461 under the

March 13, 2024 EX-4.6

Form of Subordinated Note (included in Exhibit 4.6).*

Exhibit 4.6 CORBUS PHARMACEUTICALS HOLDINGS, INC., as Issuer and ●, as Trustee INDENTURE Dated as of ● Subordinated Debt Securities CROSS REFERENCE SHEET1 Between Provisions of the Trust Indenture Act of 1939 and the Indenture to be dated as of , 20 between CORBUS PHARMACEUTICALS HOLDINGS, INC. and , as Trustee: Section of the Act Section of Indenture 310(a)(1) and (2) 5.08 310(a)(3) and (4) Inapp

March 13, 2024 S-3

As filed with the Securities and Exchange Commission on March 13, 2024

As filed with the Securities and Exchange Commission on March 13, 2024 Registration No.

March 13, 2024 EX-FILING FEES

Filing fees.*

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Corbus Pharmaceuticals Holdings, Inc.

March 13, 2024 EX-4.5

Form of Senior Note (included in Exhibit 4.5).*

Exhibit 4.5 CORBUS PHARMACEUTICALS HOLDINGS, INC., as Issuer and ●, as Trustee INDENTURE Dated as of ● Senior Debt Securities CROSS REFERENCE SHEET1 Between Provisions of the Trust Indenture Act of 1939 and the Indenture to be dated as of , 20 between CORBUS PHARMACEUTICALS HOLDINGS, INC. and , as Trustee: Section of the Act Section of Indenture 310(a)(1) and (2) 5.08 310(a)(3) and (4) Inapplicabl

March 12, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO . Commission File Number 001-37348 Corbus Pharma

March 12, 2024 EX-10.33

Form of Service Agreement between Corbus International Limited and Dominic Smethurst, dated February 27, 2024.*** †

Exhibit 10.33 This Agreement is made on February 27, 2024 Between: (1) Corbus International Limited (company number: 11195935) whose registered office is at 5 New Street Square, London, EC4A 3TW (Company, we, us); and (2) Dominic Smethurst of , , (You, your) It is agreed as follows: 1. Definitions and interpretation 1.1 This Agreement means this agreement and any schedules to this agreement which

March 12, 2024 EX-21.1

List of Subsidiaries of the Company.*

Exhibit 21.1 SUBSIDIARIES (WHOLLY-OWNED) OF CORBUS PHARMACEUTICALS HOLDINGS, INC. Name of Organization Jurisdiction Corbus Pharmaceuticals, Inc. Delaware Corbus International Limited United Kingdom Corbus Pharmaceuticals Australia Pty Ltd Australia

March 12, 2024 EX-99.1

Corbus Pharmaceuticals Reports Fourth Quarter and Year-End 2023 Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports Fourth Quarter and Year-End 2023 Financial Results and Provides Corporate Update • Encouraging CRB-701 (SYS6002) First-in Human Data Presented at ASCO-GU 2024; first patient expected to be dosed in US Ph1 study by end of March 2024 • IND Application for CRB-601 cleared; Ph1 study on track to commence in Summer of 2024 • Pre-clinical data for CRB-913 pres

March 12, 2024 EX-97.1

Compensation Recovery Policy.* †

EXHIBIT 97.1 CORBUS PHARMACEUTICALS HOLDINGS, INC. COMPENSATION RECOVERY POLICY (Adopted and approved on November 8, 2023) 1. Purpose Corbus Pharmaceuticals Holdings, Inc. (collectively with its subsidiaries, the “Company”) is committed to promoting high standards of honest and ethical business conduct and compliance with applicable laws, rules and regulations. As part of this commitment, the Comp

March 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 12, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

February 28, 2024 SC 13G

CRBP / Corbus Pharmaceuticals Holdings, Inc. / MILLENNIUM MANAGEMENT LLC Passive Investment

SC 13G 1 CRBPSC13G2024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.0001 PER SHARE (Title of Class of Securities) 21833P301 (CUSIP Number) FEBRUARY 23, 2024 (Date of event which requires filing of this statement) Check the appropria

February 14, 2024 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 tm245955d11ex-1.htm EXHIBIT 1 Exhibit 1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock, $0.0001 par value per share, of Corbus Pharmaceuticals Holdings, In

February 14, 2024 SC 13G/A

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / K2 HealthVentures Equity Trust LLC - SC 13G/A Passive Investment

SC 13G/A 1 ef20021584sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value, $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of t

February 14, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / Paradigm Biocapital Advisors LP - SC 13G Passive Investment

SC 13G 1 tm245955d11sc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 21833P301 (CUSIP Number) January 26, 2024 (Date of Event Which Requires Filing of this sta

February 14, 2024 SC 13G

CRBP / Corbus Pharmaceuticals Holdings, Inc. / K2 HealthVentures Equity Trust LLC - SC 13G Passive Investment

SC 13G 1 ef20021583sc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value, $0.0001 per share (Title of Class of Securities) 21833P103 (CUSIP Number) October 25, 2022 (Date of Event Which Requires Filing of this Sta

February 12, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / RA CAPITAL MANAGEMENT, L.P. - SC 13G Passive Investment

SC 13G 1 tm245429d27sc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) February 2, 2024 (Date of Event Which Requires Filing of this Sta

February 12, 2024 EX-99.1

Joint Filing Agreement

EX-99.1 2 tm245429d27ex1.htm EXHIBIT 1 EXHIBIT 1 AGREEMENT This Joint Filing Agreement, dated as of February 12, 2024, is by and among RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P. (the foregoing are collectively referred to herein as the “Filers”). Each of the Filers may be required to file with the United States Securities and Exchange Commissio

February 12, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / ADAGE CAPITAL PARTNERS GP, L.L.C. - CORBUS PHARMACEUTICALS HOLDINGS, INC. Passive Investment

SC 13G 1 p24-0742sc13g.htm CORBUS PHARMACEUTICALS HOLDINGS, INC. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) February 2, 2024 (Date of Event Which Requires Fili

February 9, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / INTEGRATED CORE STRATEGIES (US) LLC Passive Investment

SC 13G 1 CRBPSC13G.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.0001 PER SHARE (Title of Class of Securities) 21833P301 (CUSIP Number) JANUARY 31, 2024 (Date of event which requires filing of this statement) Check the appropriate bo

February 6, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 02, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

February 5, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 05, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

February 5, 2024 EX-99.1

Forward-Looking Statements This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform A

Connecting Innovation to Purpose Corporate Presentation February 2, 2024 NASDAQ: CRBP • CorbusPharma.

February 5, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / Cormorant Global Healthcare Master Fund, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 21833P301 (CUSIP Number) January 26, 2024 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant t

February 5, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / Paradigm Biocapital Advisors LP - SC 13G Passive Investment

SC 13G 1 tm244976d1sc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 21833P301 (CUSIP Number) January 26, 2024 (Date of Event Which Requires Filing of this stat

February 5, 2024 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 tm244976d1ex1.htm EXHIBIT 1 Exhibit 1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock, $0.0001 par value per share, of Corbus Pharmaceuticals Holdings, Inc.

February 5, 2024 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 exhibit99-1.htm Exhibit 99.1 JOINT FILING AGREEMENT This Joint Filing Agreement, dated as of February 5, 2024, is by and among Cormorant Global Healthcare Master Fund, LP, Cormorant Global Healthcare GP, LLC, Cormorant Asset Management, LP and Bihua Chen (collectively, the “Filers”). Each of the Filers may be required to file with the United States Securities and Exchange Commission a st

February 2, 2024 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 30, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdi

February 1, 2024 424B5

4,325,000 Shares of Common Stock Corbus Pharmaceuticals Holdings, Inc.

Filed Pursuant to Rule 424(b)(5) Registration No. 333-272314 PROSPECTUS SUPPLEMENT (To Prospectus dated June 13, 2023) 4,325,000 Shares of Common Stock Corbus Pharmaceuticals Holdings, Inc. We are offering 4,325,000 shares of our common stock. The public offering price is $19.00 per share. Our common stock is listed on the Nasdaq Capital Market under the symbol “CRBP.” On January 31, 2024, the las

February 1, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 30, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

February 1, 2024 EX-99.2

Corbus Pharmaceuticals Announces Pricing of Public Offering

EXHIBIT 99.2 Corbus Pharmaceuticals Announces Pricing of Public Offering Norwood, MA, Jan. 31, 2024 (GLOBE NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc. (Nasdaq: CRBP) (“Corbus” or the “Company”), a precision oncology company with a diversified portfolio, today announced the pricing of an underwritten public offering of 4,325,000 shares of its common stock at a public offering price of $19.00

February 1, 2024 EX-99.1

Corbus Pharmaceuticals Announces Proposed Public Offering

EXHIBIT 99.1 Corbus Pharmaceuticals Announces Proposed Public Offering Norwood, MA, Jan. 30, 2024 (GLOBE NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc. (Nasdaq: CRBP) (“Corbus” or the “Company”), a precision oncology company with a diversified portfolio, today announced that it plans to offer and sell shares of its common stock or, in lieu of common stock to certain investors, pre-funded warran

February 1, 2024 EX-1.1

Underwriting Agreement, dated January 31, 2024

EXHIBIT 1.1 4,325,000 Shares Corbus Pharmaceuticals Holdings, Inc. UNDERWRITING AGREEMENT January 31, 2024 Jefferies LLC 520 Madison Avenue New York, New York 10022 As Representative of the several Underwriters Ladies and Gentlemen: Introductory. Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A

January 31, 2024 S-3MEF

As filed with the Securities and Exchange Commission on January 31, 2024

As filed with the Securities and Exchange Commission on January 31, 2024 Registration No.

January 31, 2024 424B5

Shares of Common Stock Pre-Funded Warrants to Purchase Shares of Common Stock Shares of Common Stock Underlying the Pre-Funded Warrants Corbus Pharmaceuticals Holdings, Inc.

Filed Pursuant to Rule 424(b)(5) Registration No. 333-272314 The information contained in this preliminary prospectus supplement and the accompanying prospectus is not complete and may be changed. A registration statement relating to the securities has been declared effective by the Securities and Exchange Commission. This preliminary prospectus supplement and the accompanying prospectus are not a

January 31, 2024 EX-FILING FEES

Filing Fee Table

EXHIBIT 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Corbus Pharmaceuticals Holdings, Inc.

January 31, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 30, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

January 29, 2024 EX-99

JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)

EX-99 2 p24-0486exhibit99.htm JOINT FILING AGREEMENT EXHIBIT 99.1 JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing add

January 29, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 29, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

January 29, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / Point72 Asset Management, L.P. - CORBUS PHARMACEUTICALS HOLDINGS, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Corbus Pharmaceuticals Holdings, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 21833P301 (CUSIP Number) January 26, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the

January 29, 2024 424B3

Corbus Pharmaceuticals Holdings, Inc. Up to $75,000,000 Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-272314 PROSPECTUS SUPPLEMENT (To Prospectus Dated June 13, 2023) Corbus Pharmaceuticals Holdings, Inc. Up to $75,000,000 Common Stock This prospectus supplement amends and supplements the information in our prospectus, dated June 13, 2023 (the “Prospectus”), filed pursuant to our registration statement on Form S-3 (File No. 333-272314) (the “Re

January 26, 2024 EX-99.2

Forward-Looking Statements This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform A

Connecting Innovation to Purpose Corporate Presentation January 26 2024 NASDAQ: CRBP • CorbusPharma.

January 26, 2024 SC 13G

US21833P3010 / CORBUS PHARMACEUTICALS HOLDINGS INC / TANG CAPITAL PARTNERS LP Passive Investment

Securities and Exchange Commission Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

January 26, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 26, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

January 26, 2024 EX-99.1

CRB-701 (SYS6002) A Next Generation Nectin-4 Targeting Antibody Drug Conjugate Demonstrates Encouraging Safety and Efficacy in Patients with Nectin-4 Positive Tumors in First-In-Human Study Presented at ASCO-GU 2024

Exhibit 99.1 CRB-701 (SYS6002) A Next Generation Nectin-4 Targeting Antibody Drug Conjugate Demonstrates Encouraging Safety and Efficacy in Patients with Nectin-4 Positive Tumors in First-In-Human Study Presented at ASCO-GU 2024 • Q3W schedule of CRB-701 (SYS6002) demonstrates a 43% ORR and 71% DCR at predicted therapeutically relevant doses • All assessable nectin-4 positive study participants wi

January 26, 2024 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 ex991.htm EXHIBIT 99.1 Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, the undersigned agree to the joint filing of a Statement on Schedule 13G (including any and all amendments thereto) with respect to the Common Stock, $0.0001 par value per share, of Corbus Pharmaceuticals Holdings, Inc. and further agree to

January 9, 2024 EX-99.1

Corbus Pharmaceuticals Announces FDA Clearance of IND Application for its anti-αvβ8 monoclonal antibody (CRB-601)

Corbus Pharmaceuticals Announces FDA Clearance of IND Application for its anti-αvβ8 monoclonal antibody (CRB-601) • CRB-601 is designed to block the activation of latent TGFβ in the tumor microenvironment • Phase 1 clinical study set to commence H1 2024 • Pre-clinical data presented demonstrates robust anti-tumor activity in solid tumor models Norwood, MA, January 9, 2024 (GLOBE NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc.

January 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 08, 2024 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

November 14, 2023 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

November 14, 2023 EX-99.1

Forward-Looking Statements This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform A

Connecting Innovation to Purpose Corporate Presentation November 2023 NASDAQ: CRBP • CorbusPharma.

November 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

November 7, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

November 7, 2023 EX-99.1

Corbus Pharmaceuticals Reports Third Quarter 2023 Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports Third Quarter 2023 Financial Results and Provides Corporate Update • Data from dose escalation study for CRB-701, a Nectin-4 ADC to treat solid tumors, on track for release in early 2024 along with start of U.S./EU Study • IND Submission for CRB-601, an αvβ8 Monoclonal Antibody to treat solid tumors, on track for Q4 2023 • Pre-clinical data for CRB-913,

November 7, 2023 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 07, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

August 8, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

August 8, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 08, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporatio

August 8, 2023 EX-99.1

Corbus Pharmaceuticals Reports Second Quarter 2023 Financial Results and Provides Corporate Update

Corbus Pharmaceuticals Reports Second Quarter 2023 Financial Results and Provides Corporate Update • CRB-701 Phase 1 trial in China is ahead of schedule with dose escalation completion expected Q4 2023 and U.

August 3, 2023 EX-99.1

Forward-Looking Statements This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform A

Connecting Innovation to Purpose Corporate Presentation August 2023 NASDAQ: CRBP • CorbusPharma.

August 3, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 03, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporatio

June 13, 2023 424B3

Up to $16,800,000 Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-272314 PROSPECTUS Up to $16,800,000 Common Stock We have entered into an Open Market Sale AgreementSM, or sale agreement, with Jefferies LLC relating to shares of our common stock offered by this prospectus. In accordance with the terms of the sale agreement, we may offer and sell shares of our common stock having an aggregate offering price of

June 12, 2023 S-3/A

As filed with the Securities and Exchange Commission on June 12, 2023

S-3/A Table of Contents As filed with the Securities and Exchange Commission on June 12, 2023 Registration No.

June 7, 2023 CORRESP

Corbus Pharmaceuticals Holdings, Inc. 500 River Ridge Drive Norwood, MA 02062

Corbus Pharmaceuticals Holdings, Inc. 500 River Ridge Drive Norwood, MA 02062 June 7, 2023 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Corbus Pharmaceuticals Holdings, Inc. (the “Company”) Registration Statement on Form S-3 (File No. 333-272314) Ladies and Gentlemen: In accordance with Rule 461 under the S

June 1, 2023 EX-4.6

Form of Subordinated Note (included in Exhibit 4.6).*

EX-4.6 Exhibit 4.6 CORBUS PHARMACEUTICALS HOLDINGS, INC., as Issuer and •, as Trustee INDENTURE Dated as of • Subordinated Debt Securities CROSS REFERENCE SHEET1 Between Provisions of the Trust Indenture Act of 1939 and the Indenture to be dated as of , 20 between CORBUS PHARMACEUTICALS HOLDINGS, INC. and , as Trustee: Section of the Act Section of Indenture 310(a)(1) and (2) 5.08 310(a)(3) and (4

June 1, 2023 EX-1.3

Amendment No. 1 to Open Market Sale Agreement, dated May 31, 2023, by and between the Registrant and Jefferies LLC (incorporated by reference to Exhibit 1.3 of the Company’s Registration Statement on Form S-3 filed with the SEC on June 1, 2023).

EX-1.3 Exhibit 1.3 AMENDMENT NO. 1 TO OPEN MARKET SALE AGREEMENT May 31, 2023 This Amendment No. 1 (“Amendment No. 1”) amends that certain Open Market Sale Agreement, dated as of August 6, 2020 (the “Agreement”), by and between Corbus Pharmaceuticals Holdings, Inc. (the “Company”) and Jefferies LLC (the “Agent”). Defined terms used herein and not otherwise defined shall have the meaning assigned t

June 1, 2023 EX-FILING FEES

Filing fees.*

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Corbus Pharmaceuticals Holdings, Inc.

June 1, 2023 EX-4.5

Form of Senior Note (included in Exhibit 4.5).*

EX-4.5 Exhibit 4.5 CORBUS PHARMACEUTICALS HOLDINGS, INC., as Issuer and •, as Trustee INDENTURE Dated as of • Senior Debt Securities CROSS REFERENCE SHEET1 Between Provisions of the Trust Indenture Act of 1939 and the Indenture to be dated as of , 20 between CORBUS PHARMACEUTICALS HOLDINGS, INC. and , as Trustee: Section of the Act Section of Indenture 310(a)(1) and (2) 5.08 310(a)(3) and (4) Inap

June 1, 2023 S-3

As filed with the Securities and Exchange Commission on May 31, 2023

S-3 Table of Contents As filed with the Securities and Exchange Commission on May 31, 2023 Registration No.

May 19, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 9, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

May 9, 2023 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 09, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 9, 2023 EX-99

Corbus Pharmaceuticals Reports First Quarter 2023 Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports First Quarter 2023 Financial Results and Provides Corporate Update • Company expanded precision oncology pipeline with in-licensing of CRB-701: a clinical-stage Nectin-4 antibody drug conjugate (ADC) from CSPC Pharmaceutical Group • CRB-701 Phase 1 dose escalation study ongoing in patients with advanced solid tumors in China • Presented latest CRB-601 an

April 24, 2023 EX-10

Separation and General Release Agreement between the Company and Craig Millian, dated April 24, 2023 (incorporated herein by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K filed with the SEC on April 24, 2023). †

Exhibit 10.1 SEPARATION AND GENERAL RELEASE AGREEMENT This Separation and General Release Agreement (the “Agreement”) is between Craig Millian (“Millian”) and Corbus Pharmaceuticals Holdings, Inc. (“Company”), and memorializes the separation of Millian’s employment, including the severance he will receive if he (a) signs and returns this Agreement to the Company on April 14, 2023 (the “Separation

April 24, 2023 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 03, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

April 3, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Definitive Proxy State

April 3, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

March 10, 2023 EX-FILING FEES

Calculation of Filing Fee Table.*

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Corbus Pharmaceuticals Holdings, Inc.

March 10, 2023 S-8

As filed with the Securities and Exchange Commission on March 10, 2023

Table of Contents As filed with the Securities and Exchange Commission on March 10, 2023 Registration No.

March 7, 2023 EX-10

License Agreement between the Company and CSPC Megalith Biopharmaceutical Co., Ltd. (incorporated herein by reference to Exhibit 10.29 of the Company’s Annual Report on Form 10-K filed with the SEC on March 7, 2023).

Exhibit 10.29 CERTAIN IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT THE COMPANY TREATS AS PRIVATE OR CONFIDENTIAL. THE REDACTED TERMS HAVE BEEN MARKED WITH THREE ASTERISKS [***] EXCLUSIVE LICENSE AGREEMENT THIS EXCLUSIVE LICENSE AGREEMENT (this “Agreement”), dated as of February 12, 2023 (the “Effective Date”), is entered i

March 7, 2023 EX-4

Description of Capital Stock (incorporated herein by reference to Exhibit 4.10 of the Company’s Annual Report on Form 10-K filed with the SEC on March 7, 2023).

Exhibit 4.10 DESCRIPTION OF CAPITAL STOCK The following is a summary of information concerning capital stock of Corbus Pharmaceuticals Holdings, Inc. (“us,” “our,” “we” or the “Company”) and certain provisions of our amended and restated certificate of incorporation, as amended, and amended and restated bylaws, as amended, currently in effect. This summary does not purport to be complete and is qu

March 7, 2023 EX-3

Amended and Restated Certificate of Incorporation of the Company, as amended (incorporated by reference to the Company’s Annual Report on Form 10-K for the year ended December 31, 2022 filed with the SEC on March 7, 2023).

Exhibit 3.1

March 7, 2023 EX-21

List of Subsidiaries of the Company.*

Exhibit 21.1 SUSIDIARIES OF CORBUS PHARMACEUTICALS HOLDINGS, INC. Name of Organization Jurisdiction Corbus Pharmaceuticals, Inc. Delaware Corbus International Limited United Kingdom Corbus Pharmaceuticals Australia Pty Ltd Australia

March 7, 2023 EX-3

Amended and Restated Bylaws of the Company (incorporated by reference to the Company’s Annual Report on Form 10-K for the year ended December 31, 2022 filed with the SEC on March 7, 2023).

Exhibit 3.2 AMENDED AND RESTATED BYLAWS OF CORBUS PHARMACEUTICALS HOLDINGS, INC. (the “Corporation”) ARTICLE I Stockholders SECTION 1. (a) Annual Meeting. The annual meeting of stockholders (any such meeting being referred to in these Bylaws as an “Annual Meeting”) shall be held at the hour, date and place, if any, within or without the United States which is fixed by the Board of Directors of the

March 7, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 03, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

March 7, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO . Commission File Number 001-37348 Corbus Pharma

March 7, 2023 EX-99

Corbus Pharmaceuticals Reports Fourth Quarter 2022 and Year-End Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports Fourth Quarter 2022 and Year-End Financial Results and Provides Corporate Update • Company expands precision oncology pipeline with licensing of CRB-701, clinical-stage Nectin-4 antibody drug conjugate (ADC) from CSPC Pharmaceutical Group • CRB-701 Phase 1 dose escalation ongoing in China in patients with advanced solid tumors • CRB-601 anti-αvβ8 mAb pro

March 7, 2023 EX-99

Forward-Looking Statements This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform A

Connecting Innovation to Purpose Corporate Presentation March 2023 NASDAQ: CRBP • CorbusPharma.

March 6, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 01, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

March 6, 2023 EX-99

Corbus Pharmaceuticals Expands Board of Directors with Appointment of Yong Ben, M.D., MBA

Exhibit 99.1 Corbus Pharmaceuticals Expands Board of Directors with Appointment of Yong Ben, M.D., MBA Norwood, MA, March 6, 2023 (PR NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”), a precision oncology company, today announced the appointment of Yong Ben, M.D., MBA, to the Company’s Board of Directors. “Dr. Ben is a distinguished oncology researcher a

February 15, 2023 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 09, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorpor

February 13, 2023 EX-99

Forward-Looking Statements This presentation contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform A

Connecting Innovation to Purpose Corporate Presentation February 2023 NASDAQ: CRBP • CorbusPharma.

February 13, 2023 8-K

Regulation FD Disclosure, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 09, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

February 13, 2023 EX-3

Certificate of Amendment to the Amended and Restated Certificate of Incorporation of Corbus Pharmaceuticals Holdings, Inc., dated February 9, 2023

EX-3 2 crbp-ex31.htm EX-3.1 Exhibit 3.1 CERTIFICATE OF AMENDMENT TO THE AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF CORBUS PHARMACEUTICALS HOLDINGS, INC. Corbus Pharmaceuticals Holdings, Inc. (the “Corporation”), a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware, does hereby certify as follows: FIRST: The name of the Corporati

February 13, 2023 EX-99

Corbus Pharmaceuticals expands oncology pipeline with the addition of a clinical stage Nectin-4 targeting Antibody Drug Conjugate (ADC)

Exhibit 99.1 Corbus Pharmaceuticals expands oncology pipeline with the addition of a clinical stage Nectin-4 targeting Antibody Drug Conjugate (ADC) • CRB-701 (SYS6002) is designed for improved therapeutic index and to act on a broad range of Nectin-4 expressing tumors • Clinical development is underway and will focus on urothelial cancer and other Nectin-4-positive solid tumors potentially includ

January 6, 2023 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 04, 2023 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

December 21, 2022 EX-99.1

Corbus Pharmaceuticals Reports Third Quarter 2022 Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports Third Quarter 2022 Financial Results and Provides Corporate Update ? Latest pre-clinical data for CRB-601 monotherapy and in combination with anti-PD1 therapy to be presented this Thursday at SITC 2022 ? IND submission for CRB-601 is on track for mid-2023 ? Expanding oncology pipeline through strategic transactions remains key priority ? Cash and investm

December 21, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

December 21, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 08, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

November 14, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Definitive Proxy State

November 8, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

s UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

November 4, 2022 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Definitive Proxy State

October 31, 2022 EX-10.1

Second Amendment to Loan and Security Agreement, dated as of July 28, 2020, by and between Corbus Pharmaceuticals Holdings, Inc., Corbus Pharmaceuticals, Inc., K2 HealthVentures LLC and Ankura Trust Company, LLC (incorporated by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K filed with the SEC on October 31, 2022).

Exhibit 10.1 SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT This SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT (this ?Amendment?) entered into as of October 25, 2022, by and among Corbus Pharmaceuticals, Inc., a Delaware corporation (?Borrower Representative?), and each other Person party thereto as a borrower from time to time (together with the Borrower Representative, collectively, ?Borrower

October 31, 2022 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 25, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

October 12, 2022 8-A12G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 46-4348039 (State or other jurisdiction of incorporation or organization) (IRS Employer Ident

October 12, 2022 EX-3.2

Certificate of Designation of the Series A Preferred Stock of the Company, dated October 12, 2022.

EX-3.2 3 crbp-ex32.htm EX-3.2 Exhibit-3.2 CORBUS PHARMACEUTICALS HOLDINGS, INC. CERTIFICATE OF DESIGNATION OF SERIES A PREFERRED STOCK Pursuant to Section 151 of the General Corporation Law of the State of Delaware THE UNDERSIGNED DOES HEREBY CERTIFY, on behalf of Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation (the “Corporation”), that the following resolution was duly adopted by th

October 12, 2022 EX-3.1

Amendment to Bylaws.

Exhibit-3.1 AMENDMENT NO. 2 TO THE AMENDED AND RESTATED BYLAWS OF CORBUS PHARMACEUTICAL HOLDINGS, INC. (the “Corporation”) Article I of the Amended and Restated Bylaws of Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation, as amended to date (the “Bylaws”), is hereby amended as follows: Article I, Section 5 of the Bylaws be, and hereby is, amended to read in its entirety as follows: “SE

October 12, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 11, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

September 26, 2022 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 20, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorpora

September 26, 2022 EX-99.1

Corbus Pharmaceuticals Appoints Anne Altmeyer, PhD to Board of Directors

Corbus Pharmaceuticals Appoints Anne Altmeyer, PhD to Board of Directors Norwood, MA, September 26, 2022 (GLOBE NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc.

August 24, 2022 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings Inc / ETF MANAGERS GROUP, LLC - AMENDMENT NO. 18 TO SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 18)* Corbus Pharmaceuticals Holdings Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 21833P103 (CUSIP Number) August 23, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to d

August 9, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 09, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporatio

August 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

August 9, 2022 EX-99.1

Corbus Pharmaceuticals Reports Second Quarter 2022 Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports Second Quarter 2022 Financial Results and Provides Corporate Update ? Promising pre-clinical data generated for CRB-601 across several tumor models as monotherapy and in combination with anti-PD1 therapy ? IND submission for CRB-601 is on track for mid-2023 ? Expanding immuno-oncology pipeline through strategic transactions remains key priority ? Cash an

July 7, 2022 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 06, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

June 8, 2022 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 08, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

June 8, 2022 EX-99.1

Investor Presentation

May 23, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 17, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 12, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 10, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 10, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation)

May 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

May 10, 2022 EX-99.1

Corbus Pharmaceuticals Reports First Quarter 2022 Financial Results and Provides Corporate Update

Exhibit 99.1 Corbus Pharmaceuticals Reports First Quarter 2022 Financial Results and Provides Corporate Update ? Promising pre-clinical data generated for CRB-601 across several tumor models as monotherapy and in combination with anti-PD1 therapy ? IND submission for CRB-601 is on-track for the first half of 2023 ? Expanding immuno-oncology pipeline through strategic transactions remains key prior

April 15, 2022 EX-10.3

Form of Second Amended and Restated Employment Agreement between Corbus Pharmaceuticals Holdings, Inc. and Craig Millian (incorporated by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K, filed with the SEC on April 15, 2022). †

Exhibit 10.3 SECOND AMENDED AND RESTATED EMPLOYMENT AGREEMENT This SECOND AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this ?Agreement?), effective as of April 11, 2022 (the ?Effective Date?), is between Corbus Pharmaceuticals Holdings, Inc. (the ?Company?) and Craig Millian (the ?Executive?). WITNESSETH: WHEREAS, the Executive has been employed by the Company as its Chief Operating Officer pursuant

April 15, 2022 EX-10.2

Form of Fifth Amended and Restated Employment Agreement between Corbus Pharmaceuticals Holdings, Inc. and Sean Moran (incorporated by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K, filed with the SEC on April 15, 2022). †

Exhibit 10.2 FIFTH AMENDED AND RESTATED EMPLOYMENT AGREEMENT This FIFTH AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this ?Agreement?), effective as of April 11, 2022 (the ?Effective Date?), is between Corbus Pharmaceuticals Holdings, Inc. (the ?Company?) and Sean Moran (the ?Executive?). WITNESSETH: WHEREAS, the Executive has been employed by the Company as its Chief Financial Officer pursuant to t

April 15, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 11, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

April 15, 2022 EX-10.1

Form of Fourth Amended and Restated Employment Agreement between Corbus Pharmaceuticals Holdings, Inc. and Yuval Cohen (incorporated by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K, filed with the SEC on April 15, 2022). †

Exhibit 10.1 FOURTH AMENDED AND RESTATED EMPLOYMENT AGREEMENT This Fourth Amended and Restated Employment Agreement (this ?Agreement?), effective as of April 11, 2022 (the ?Effective Date?), is between Corbus Pharmaceuticals Holdings, Inc. (the ?Company?) and Yuval Cohen (the ?Executive?). WITNESSETH: WHEREAS, the Executive has been employed by the Company as its Chief Executive Officer pursuant t

April 11, 2022 EX-99.1

Corbus Presents First Preclinical Data for CRB-601 at the American Association for Cancer Research (AACR) Annual Meeting

Corbus Presents First Preclinical Data for CRB-601 at the American Association for Cancer Research (AACR) Annual Meeting Norwood, MA, April 8, 2022 (GLOBE NEWSWIRE) - Corbus Pharmaceuticals Holdings, Inc.

April 11, 2022 EX-99.3

Investor Presentation

April 11, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 08, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

April 11, 2022 EX-99.2

AARC Poster

April 1, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

April 1, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

March 15, 2022 EX-FILING FEES

Calculation of Filing Fee Table.*

Exhibit 107 CALCULATION OF FILING FEE TABLE Form S-8 (Form Type) Corbus Pharmaceuticals Holdings, Inc.

March 15, 2022 S-8

As filed with the Securities and Exchange Commission on March 15, 2022

Table of Contents As filed with the Securities and Exchange Commission on March 15, 2022 Registration No.

March 8, 2022 EX-21.1

List of Subsidiaries of the Company.*

Exhibit 21.1 SUSIDIARIES OF CORBUS PHARMACEUTICALS HOLDINGS, INC. Name of Organization Jurisdiction Corbus Pharmaceuticals, Inc. Delaware Corbus International Limited United Kingdom Corbus Pharmaceuticals Australia Pty Ltd Australia

March 8, 2022 EX-99.1

Corbus Pharmaceuticals Reports Fourth Quarter and Year-End 2021 Financial Results and Provides Corporate Updates

Exhibit 99.1 Corbus Pharmaceuticals Reports Fourth Quarter and Year-End 2021 Financial Results and Provides Corporate Updates ? Company is advancing its integrin program and on schedule for initiating clinical studies in 2023 ? Expanding immuno-oncology pipeline through strategic transactions remains key priority ? Cash and investments on hand of $98.3 million funds operations into the first quart

March 8, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO . Commission File Number 001-37348 Corbus Pharma

March 8, 2022 EX-10.31

Employment Agreement between the Company and Rachael Brake, effective as of December 6, 2021(incorporated herein by reference to Exhibit 10.31 of the Company’s Annual Report on Form 10-K filed with the SEC on March 8, 2022). †

Exhibit 10.31 EMPLOYMENT AGREEMENT This Employment Agreement (this ?Agreement?), effective as of December 6, 2021 (the ?Effective Date?), is between Corbus Pharmaceuticals Holdings, Inc. (the ?Company?) and Rachael Brake (the ?Executive?). WITNESSETH: WHEREAS, the Company desires to employ the Executive as its Chief Scientific Officer, and the Executive desires to accept such employment, on the te

March 8, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 08, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporation

March 8, 2022 EX-4.10

Description of Capital Stock*

Exhibit 4.10 DESCRIPTION OF CAPITAL STOCK The following is a summary of information concerning capital stock of Corbus Pharmaceuticals Holdings, Inc. (?us,? ?our,? ?we? or the ?Company?) and certain provisions of our amended and restated certificate of incorporation and amended and restated bylaws currently in effect. This summary does not purport to be complete and is qualified in its entirety by

February 14, 2022 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings Inc / ETF MANAGERS GROUP, LLC - AMENDMENT NO. 17 TO SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 17)* Corbus Pharmaceuticals Holdings Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 21833P103 (CUSIP Number) February 11, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to

January 3, 2022 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 03, 2022 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporati

November 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

November 12, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-37348 46-4348039 (State or Other Jurisdiction of Incorporat

November 12, 2021 EX-99.1

Corbus Pharmaceuticals Reports Third Quarter 2021 Financial Results and Provides Corporate Updates

Exhibit 99.1 Corbus Pharmaceuticals Reports Third Quarter 2021 Financial Results and Provides Corporate Updates ? Company continues to advance integrin program from preclinical development toward the clinic ? Expanding pipeline through strategic transactions remains key priority ? Cash and investments on hand of $108 million sufficient to support execution of research, clinical and operational goa

September 28, 2021 EX-10.1

Amendment to Employment Agreement between Corbus Pharmaceuticals Holdings, Inc., and Craig Millian, effective as of September 27, 2021.

Exhibit 10.1 SECOND AMENDMENT TO EMPLOYMENT AGREEMENT This Second Amendment to Employment Agreement (the ?Amendment?) is made and entered into between Corbus Pharmaceuticals Holdings, Inc. (the ?Company?) and Craig Millian (the ?Executive?) effective as of September 27, 2021 (the ?Effective Date?). WHEREAS, Company and the Executive are parties to an Amended and Restated Employment Agreement dated

September 28, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 24, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction (Commission

September 22, 2021 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 16, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction of incorporat

September 22, 2021 EX-10.1

Separation and General Release Agreement between the Company and Barbara White, dated September 17, 2021 (incorporated by reference to Exhibit 10.1 of the Company’s Current Report on Form 8-K, filed with the SEC on September 22, 2021). †

Exhibit 10.1 SEPARATION AND GENERAL RELEASE AGREEMENT This Separation and General Release Agreement (the ?Agreement?) is between Barbara White (?White?) and Corbus Pharmaceuticals, Inc. (?Company?), and memorializes the separation of White?s employment, including the severance she will receive if she (a) signs and returns this Agreement to the Company on September 17, 2021 (the ?Separation Date?)

August 18, 2021 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 16, 2021 CORBUS PHARMACEUT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 16, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction (Commission (IR

August 12, 2021 EX-99.1

Corbus Pharmaceuticals Reports Second Quarter 2021 Financial Results and Provides Corporate Updates

Exhibit 99.1 Corbus Pharmaceuticals Reports Second Quarter 2021 Financial Results and Provides Corporate Updates ? Company focused on gaining regulatory clarity for late-stage lenabasum program and advancing programs targeting the endocannabinoid system and integrins into the clinic ? Augmenting the pipeline through business development continues to be a priority ? Cash and investments on hand of

August 12, 2021 EX-10.1

License Agreement between the Company and Milky Way BioPharma, LLC, dated May 25, 2021 (incorporated by reference to Exhibit 10.1 of the Company’s Quarterly Report on Form 10-Q filed with the SEC on August 12, 2021).#

Exhibit 10.1 CERTAIN IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT THE COMPANY TREATS AS PRIVATE OR CONFIDENTIAL. THE REDACTED TERMS HAVE BEEN MARKED WITH THREE ASTERISKS [***] LICENSE AGREEMENT This License Agreement (?Agreement?) is entered into and made effective as of May 25th, 2021 (?Effective Date?) by and between Mil

August 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

August 12, 2021 EX-10.2

License Agreement between the Company and The Regents of the University of California, dated May 26, 2021 (incorporated by reference to Exhibit 10.2 of the Company’s Quarterly Report on Form 10-Q filed with the SEC on August 12, 2021).#

Exhibit 10.2 CERTAIN IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT THE COMPANY TREATS AS PRIVATE OR CONFIDENTIAL. THE REDACTED TERMS HAVE BEEN MARKED WITH THREE ASTERISKS [***] EXCLUSIVE LICENSE AGREEMENT between THE REGENTS OF THE UNIVERSITY OF CALIFORNIA and CORBUS PHARMACEUTICALS, INC. for BLOCKING HUMANIZED ANTIBODIES T

August 12, 2021 8-K

Results of Operations and Financial Condition, Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction (Commission (IR

August 12, 2021 EX-3.1

Amended and Restated Certificate of Incorporation of the Company, as amended (incorporated by reference to Exhibit 3.1 of the Company’s Quarterly Report on Form 10-Q filed with the SEC on August 12, 2021).

EX-3.1 2 ex3-1.htm Exhibit 3.1

July 22, 2021 EX-99.1

Investor Presentation

EX-99.1 2 ex99-1.htm Exhibit 99.1

July 22, 2021 8-K

Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 22, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction (Commission (IRS

June 24, 2021 8-K

Regulation FD Disclosure, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 24, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction of incorporation)

June 24, 2021 EX-99.1

Corbus Pharmaceuticals Announces Topline Results from determine Phase 3 Study of Lenabasum for Treatment of Dermatomyositis

EX-99.1 2 ex99-1.htm Exhibit 99.1 Corbus Pharmaceuticals Announces Topline Results from determine Phase 3 Study of Lenabasum for Treatment of Dermatomyositis ● Study did not meet primary endpoint of Total Improvement Score (TIS) at Week 28 ● Additional findings included nominally significant improvements in TIS (p = 0.0302) and CDASI (p = 0.0166) depending on the dermatomyositis subtype ● Lenabasu

June 17, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Submission of Matters to a Vote of Security Holders, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction (Commission (IRS

June 17, 2021 EX-3.1

Certificate of Amendment of the Certificate of Incorporation, as amended, dated June 17, 2021

Exhibit 3.1

June 1, 2021 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Regulation FD Disclosure, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 25, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction (Commission (IRS E

June 1, 2021 EX-99.1

Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases

EX-99.1 2 ex99-1.htm Exhibit 99.1 Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases ● Corbus diversifies pipeline with two new mAbs that target integrins that inhibit activation of TGFβ ● High potency anti- αvβ8 mAb licensed from University of California San Francisco and anti- αvβ6/ αvβ8 mAb licensed from Panorama Research Inc

June 1, 2021 SC 13G/A

CRBP / Corbus Pharmaceuticals Holdings Inc / ETF MANAGERS GROUP, LLC - AMENDMENT NO.16 TO SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 16)* Corbus Pharmaceuticals Holdings Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 21833P103 (CUSIP Number) May 28, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to desi

June 1, 2021 EX-99.2

Investor Presentation

EX-99.2 3 ex99-2.htm Exhibit 99.2

May 19, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Information required in proxy statement schedule 14A information PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Information required in proxy statement schedule 14A information PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant [X] Filed by a Party other than the Registrant [ ] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, for Use of the Co

May 13, 2021 8-K

Results of Operations and Financial Condition, Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2021 CORBUS PHARMACEUTICALS HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37348 46-4348039 (State or other jurisdiction (Commission (IRS E

May 13, 2021 EX-99.1

Corbus Pharmaceuticals Reports First Quarter 2021 Financial Results and Provides Corporate Updates

Exhibit 99.1 Corbus Pharmaceuticals Reports First Quarter 2021 Financial Results and Provides Corporate Updates ? Phase 3 study of lenabasum in dermatomyositis on schedule for topline data in Q2 2021 ? Company focused on advancing cannabinoid programs in metabolic diseases and cancer into the clinic in 2022 ? Corbus is actively engaging with potential partners to expand its pipeline through acquis

May 13, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to.

May 11, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 15)*

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 15)* Corbus Pharmaceuticals Holdings Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 21833P103 (CUSIP Number) May 10, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to desi

April 6, 2021 DEF 14A

Definitive Proxy Statement

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant [X] Filed by a Party other than the Registrant [ ] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) [X] Definitive P

April 6, 2021 DEFA14A

-

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant [X] Filed by a Party other than the Registrant [ ] Check the appropriate box: [ ] Preliminary Proxy Statement [ ] Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) [ ] Definitive P

March 26, 2021 PRE 14A

-

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant [X] Filed by a Party other than the Registrant [ ] Check the appropriate box: [X] Preliminary Proxy Statement [ ] Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) [ ] Definitive P

March 17, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 14)*

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 14)* Corbus Pharmaceuticals Holdings Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 21833P103 (CUSIP Number) March 16, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to de

March 16, 2021 S-8

-

As filed with the Securities and Exchange Commission on March 16, 2021 Registration No.

March 15, 2021 EX-21.1

List of Subsidiaries of the Company.*

EX-21.1 2 ex21-1.htm Exhibit 21.1 SUSIDIARIES OF CORBUS PHARMACEUTICALS HOLDINGS, INC. Name of Organization Jurisdiction Corbus Pharmaceuticals, Inc. Delaware Corbus International Limited United Kingdom Corbus Pharmaceuticals Australia Pty Ltd Australia

Other Listings
DE:3371
GB:0SZI
Fintel data has been cited in the following publications:
Daily Mail Fox Business Business Insider Wall Street Journal The Washington Post Bloomberg Financial Times Globe and Mail
NASDAQ.com Reuters The Guardian Associated Press FactCheck.org Snopes Politifact
Federal Register The Intercept Forbes Fortune Magazine TheStreet Time Magazine Canadian Broadcasting Corporation International Business Times
Cambridge University Press Investopedia MarketWatch NY Daily News Entrepreneur Newsweek Barron's El Economista