PLXP / PLx Pharma Inc. - Pemfailan SEC, Laporan Tahunan, Penyata Proksi

PLx Pharma Inc.
US ˙ NASDAQ
SIMBOL INI TIDAK AKTIF LAGI

Statistik Asas
LEI 549300KEXDQRVGRQPE70
CIK 1497504
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to PLx Pharma Inc.
SEC Filings (Chronological Order)
Halaman ini menyediakan senarai kronologi lengkap bagi Pemfailan SEC, tidak termasuk pemfailan pemilikan yang kami sediakan di tempat lain.
October 18, 2023 15-12G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File Number: 001-36351 PLx Pharma Winddown Corp. (Exact name of registrant as specified

September 20, 2023 EX-2.1

Case 23-10456-MFW Doc 279 Filed 09/14/23 Page 1 of 20 IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE

Case 23-10456-MFW Doc 279 Filed 09/14/23 Page 1 of 20 IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE ) In re: ) Chapter 11 ) PLX PHARMA WINDDOWN CORP.

September 20, 2023 8-K

Financial Statements and Exhibits, Other Events, Bankruptcy or Receivership

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 - FORM 8-K - CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 14, 2023 - PLx Pharma Winddown Corp. (Exact name of Registrant as Specified in Its Charter) - Delaware (State or Other Jurisdiction of Incorporation) 001-36351 (Commissi

September 20, 2023 8-K

EXHIBIT 99.1

UST Form 11-MOR (12/01/2021) 1 UNITED STATES BANKRUPTCY COURT DISTRICT OF DELAWARE In Re.

August 22, 2023 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 - FORM 8-K - CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 21, 2023 - PLx Pharma Winddown Corp. (Exact name of Registrant as Specified in Its Charter) - Delaware (State or Other Jurisdiction of Incorporation) 001-36351 (Commission

August 22, 2023 8-K

8-K

UST Form 11-MOR (12/01/2021) 1 UNITED STATES BANKRUPTCY COURT DISTRICT OF DELAWARE In Re.

July 21, 2023 8-K

Current Report

UST Form 11-MOR (12/01/2021) 1 UNITED STATES BANKRUPTCY COURT DISTRICT OF DELAWARE In Re.

July 21, 2023 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 - FORM 8-K - CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 20, 2023 - PLx Pharma Winddown Corp. (Exact name of Registrant as Specified in Its Charter) - Delaware (State or Other Jurisdiction of Incorporation) 001-36351 (Commission Fi

July 12, 2023 8-K

Current Report

30518734.2 **THIS IS NOT A SOLICITATION OF AN ACCEPTANCE OR REJECTION OF THIS COMBINED DISCLOSURE STATEMENT AND PLAN. ACCEPTANCES OR REJECTIONS MAY NOT BE SOLICITED UNTIL THE COMBINED DISCLOSURE STATEMENT AND PLAN HAS BEEN PROVISIONALLY APPROVED BY THE BANKRUPTCY COURT.** IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE ) In re: ) Chapter 11 ) PLX PHARMA WINDDOWN CORP., et al., 1

July 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 7, 2023 PLx Pharma Winddown

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 - FORM 8-K - CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 7, 2023 - PLx Pharma Winddown Corp. (Exact name of Registrant as Specified in Its Charter) - Delaware (State or Other Jurisdiction of Incorporation) 001-36351 (Commission Fil

July 7, 2023 EX-3.1

AMENDMENT NO. 1 AMENDED AND RESTATED BYLAWS PLX PHARMA WINDDOWN CORP.

Exhibit 3.1 AMENDMENT NO. 1 TO AMENDED AND RESTATED BYLAWS OF PLX PHARMA WINDDOWN CORP. The Amended and Restated Bylaws (the “Bylaws”) of PLx Pharma Winddown Corp., formerly known as PLx Pharma Inc. (the “Corporation”), are hereby amended by: (a) Changing all references to the name of the Corporation from “PLx Pharma Inc.” to “PLx Pharma Winddown Corp.”; (b) Amending and restating Article 6, Secti

July 7, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30, 2023 PLx Pharma Winddown

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 - FORM 8-K - CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30, 2023 - PLx Pharma Winddown Corp. (Exact name of Registrant as Specified in Its Charter) - Delaware (State or Other Jurisdiction of Incorporation) 001-36351 (Commission Fi

June 27, 2023 8-K

MONTHLY OPERATING REPORTS

UST Form 11-MOR (12/01/2021) 1 UNITED STATES BANKRUPTCY COURT DISTRICT OF DELAWARE In Re.

June 27, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 PLx Pharma Winddown

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 - FORM 8-K - CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 21, 2023 - PLx Pharma Winddown Corp. (Exact name of Registrant as Specified in Its Charter) - Delaware (State or Other Jurisdiction of Incorporation) 001-36351 (Commission Fi

May 26, 2023 EX-10.1

AMENDMENT NO. 1 TO ASSET PURCHASE AGREEMENT

AMENDMENT NO. 1 TO ASSET PURCHASE AGREEMENT This Amendment No. 1 (this “Amendment”) to the Asset Purchase Agreement (the “Agreement”) entered into and effective as of April 12, 2023, is entered into as of May 26, 2023, by and among PLx Pharma Inc., a Delaware corporation (the “Company”) and PLx Opco Inc., a Delaware corporation and a wholly-owned subsidiary of the Company (together with the Compan

May 26, 2023 EX-3.1

CERTIFICATE OF AMENDMENT TO THE CERTIFICATE OF INCORPORATION PLX PHARMA INC. _______________________________________________ Pursuant to Section 242 of the General Corporation Law of the State of Delaware

CERTIFICATE OF AMENDMENT TO THE CERTIFICATE OF INCORPORATION OF PLX PHARMA INC. Pursuant to Section 242 of the General Corporation Law of the State of Delaware IT IS HEREBY CERTIFIED THAT: 1. The name of the corporation is: PLx Pharma Inc. (the “Corporation”). The original Certificate of Incorporation of the Corporation was filed with the Secretary of State of the State of Delaware on March 12, 20

May 26, 2023 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets, Other Events, Bankruptcy or Receivership

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 - FORM 8-K - CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 26, 2023 - PLx Pharma Winddown Corp. (Exact name of Registrant as Specified in Its Charter) - Delaware (State or Other Jurisdiction of Incorporation) 001-36351 (Commission Fil

May 26, 2023 8-K

MONTHLY OPERATING REPORTS

UST Form 11-MOR (12/01/2021) 1 UNITED STATES BANKRUPTCY COURT DISTRICT OF DELAWARE In Re.

April 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 13, 2023 PLx Pharma Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 13, 2023 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Num

April 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 12, 2023 PLx Pharma Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 12, 2023 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Num

April 12, 2023 EX-99.1

PLx Pharma Inc. Enters into a Stalking Horse Asset Purchase Agreement to Sell VAZALORE® and Substantially All of its Assets

For Immediate Release PLx Pharma Inc. Enters into a Stalking Horse Asset Purchase Agreement to Sell VAZALORE® and Substantially All of its Assets Sparta, New Jersey, April 12, 2023 - PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), is a commercial-stage drug delivery platform technology company focused on its clinically-validated and patent-protected PLxGuard™ and VAZALORE®, an FDA-approve

April 12, 2023 EX-10.1

ASSET PURCHASE AGREEMENT dated as of April 12, 2023 by and among PLx Acquisition Company, LLC as Buyer, PLx Pharma Inc. PLX OPCO INC., as Sellers

Exhibit 10.1 ASSET PURCHASE AGREEMENT dated as of April 12, 2023 by and among PLx Acquisition Company, LLC as Buyer, and PLx Pharma Inc. and PLX OPCO INC., as Sellers Table of Contents Page: Article I. Definitions 1 1.1 Defined Terms. 1 1.2 Interpretation. 16 Article II. Acquired Assets and Assumption Of Liabilities 17 2.1 Assets to be Acquired. 17 2.2 Excluded Assets. 18 2.3 Liabilities to be Ass

April 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 4, 2023 PLx Pharma Inc. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 4, 2023 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Numb

April 6, 2023 SC 13G

PLXP / PLx Pharma Inc. / Park West Asset Management LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.)* PLx Pharma Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 72942A107 (CUSIP Number) April 4, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant

April 6, 2023 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 ex99-1.htm Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of them of a statement on Schedule 13G (including amendments thereto) with respect to the shares of common stock, $0.001 par value per share, of PLx Pharma Inc., a Delaware corporation, and furth

March 8, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 7, 2023 PLx Pharma Inc. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 7, 2023 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Numb

February 14, 2023 SC 13G/A

PLXP / PLx Pharma Inc / MSD Partners, L.P. - SC 13G/A Passive Investment

SC 13G/A CUSIP No. 72942A107 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.1)* PLX PHARMA INC. (Name of Issuer) Common Stock, $.001 par value per share (Title of Class of Securities) 72942A107 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate b

February 14, 2023 EX-99.1

Joint Filing Agreement dated February 14, 2023.

EX-99.1 2 d406333dex991.htm EX-99.1 CUSIP No. 72942A107 Exhibit 99.1 AGREEMENT REGARDING THE JOINT FILING OF SCHEDULE 13G The undersigned hereby agree as follows: (i) Each of them is individually eligible to use the Schedule 13G to which this Exhibit is attached, and such Schedule 13G is filed on behalf of each of them; and (ii) Each of them is responsible for the timely filing of such Schedule 13

February 13, 2023 EX-10.3

Form of Award Notice under PLx Pharma Inc. 2023 Key Executive Retention Plan

PLX PHARMA INC. 2023 KEY EXECUTIVE RETENTION PLAN AWARD NOTICE PLx Pharma Inc. (the “Company”), pursuant to the Company’s 2023 Key Executive Retention Plan (“Plan”), hereby grants to the Participant named below a Retention Payment (the “Retention Payment”) in the amount set forth below. The award is subject to all of the terms and conditions as set forth in this notice (this “Award Notice”) and th

February 13, 2023 EX-10.2

PLx Pharma Inc. 2023 Key Executive Retention Plan

PLX PHARMA INC. 2023 KEY EXECUTIVE RETENTION PLAN Article 1 PURPOSE Section 1.01. Purpose. The purpose of the 2023 Key Executive Retention Plan (the “Plan”) of PLx Pharma Inc. (the “Company”) is to provide selected key executives of the Company and its affiliates (including PLx Opco Inc.) Retention Payments that are intended to provide an incentive to complete the restructure of the Company’s oper

February 13, 2023 EX-10.5

Award Notice, by and between PLx Pharma Inc. and Rita O’Connor, dated February 13, 2023.

PLX PHARMA INC. 2023 KEY EXECUTIVE RETENTION PLAN AWARD NOTICE PLx Pharma Inc. (the “Company”), pursuant to the Company’s 2023 Key Executive Retention Plan (“Plan”), hereby grants to the Participant named below a Retention Payment (the “Retention Payment”) in the amount set forth below. The award is subject to all of the terms and conditions as set forth in this notice (this “Award Notice”) and th

February 13, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 7, 2023 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File N

February 13, 2023 EX-10.1

Severance and Settlement Agreement and Release of All Claims, dated February 9, 2023, by and between the Company and Michael Valentino.

SEVERANCE AND SETTLEMENT AGREEMENT AND RELEASE OF ALL CLAIMS THIS SEVERANCE AND SETTLEMENT AGREEMENT AND RELEASE OF ALL CLAIMS is by and between MICHAEL J.

February 13, 2023 EX-10.4

Award Notice, by and between PLx Pharma Inc. and Natasha Giordano, dated February 13, 2023.

PLX PHARMA INC. 2023 KEY EXECUTIVE RETENTION PLAN AWARD NOTICE PLx Pharma Inc. (the “Company”), pursuant to the Company’s 2023 Key Executive Retention Plan (“Plan”), hereby grants to the Participant named below a Retention Payment (the “Retention Payment”) in the amount set forth below. The award is subject to all of the terms and conditions as set forth in this notice (this “Award Notice”) and th

January 20, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 14, 2023 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File N

November 10, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 8, 2022 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File N

November 10, 2022 EX-99.1

PLx Pharma Inc. Reports Third Quarter 2022 Results and Provides Business Update - Significant Reduction in Operating Expenses - Strategic Alternatives Process Ongoing

For Immediate Release PLx Pharma Inc. Reports Third Quarter 2022 Results and Provides Business Update - Significant Reduction in Operating Expenses - Strategic Alternatives Process Ongoing ? Total Net Sales of $0.4 Million, Including $0.3 Million of Unfavorable Adjustments for Additional Trade Allowances and Incremental Sales Returns Reserves in Q3 2022 ? Total Operating Expenses Significantly Low

November 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ? Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended September 30, 2022 Or ? Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 Commission File Number 001-36351 P

October 7, 2022 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 7, 2022 (October 3, 2022) PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (

September 29, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

September 29, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

August 12, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ? Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 30, 2022 Or ? Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 Commission File Number 001-36351 PLx Ph

August 12, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 12, 2022 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Nu

August 12, 2022 EX-99.1

PLx Pharma Inc. Reports Second Quarter 2022 Results and Provides Business Update - Initiates Evaluation of Strategic Alternatives to Enhance Stockholder Value - Reports Positive Results of VAZALORE® 81 mg Patient Experience Survey - Streamlines Sales

For Immediate Release PLx Pharma Inc. Reports Second Quarter 2022 Results and Provides Business Update - Initiates Evaluation of Strategic Alternatives to Enhance Stockholder Value - Reports Positive Results of VAZALORE? 81 mg Patient Experience Survey - Streamlines Sales & Marketing Plan ? Total Net Sales of $0.5 Million, Including $0.4 Million of Unfavorable Adjustments for Additional Trade Allo

May 13, 2022 EX-99.1

PLx Pharma Inc. Reports First Quarter 2022 Results and Provides Business Update BUILDING A SOLID BASE OF VAZALORE® USERS

For Immediate Release PLx Pharma Inc. Reports First Quarter 2022 Results and Provides Business Update BUILDING A SOLID BASE OF VAZALORE? USERS ? Total Net Sales of $2.1 Million in the First Quarter of 2022, an Increase of Approximately 31% from Fourth Quarter of 2021 ? GAAP Net Loss of ($0.39) Per Diluted Share in the First Quarter 2022; Adjusted Non-GAAP Net Loss Per Diluted Share of ($0.66) ? Ca

May 13, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 13, 2022 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Numbe

May 13, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ? Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended March 31, 2022 Or ? Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 Commission File Number 001-36351 PLx P

April 29, 2022 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 -12-31FY2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commissi

April 21, 2022 EX-3.1

Amended and Restated Bylaws of PLx Pharma Inc.

AMENDED AND RESTATED BYLAWS OF PLX PHARMA INC. (a Delaware Corporation) PLx Pharma Inc., a Delaware corporation (the ?Corporation?), pursuant to the provisions of Section 109 of the Delaware General Corporation Law (?DGCL?), hereby adopts these Amended and Restated Bylaws (the ?Bylaws?), which restate, amend and supersede the bylaws of the Corporation, as previously amended and restated, in their

April 21, 2022 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 20, 2022 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Num

March 15, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 15, 2022 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Num

March 15, 2022 8-K

8-K

March 11, 2022 EX-4.6

Description of Registered Securities.*

Exhibit 4.6 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 PLx Pharma Inc. (the ?Company?) has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the ?Exchange Act?): its common stock, par value $0.001 per share (?Common Stock?). The following is a summary of the material terms

March 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 11, 2022 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Num

March 11, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-36351 PLX PHAR

March 11, 2022 EX-99.1

PLx Pharma Inc. Reports Fourth Quarter and Full Year 2021 Results and Provides Business Update MOMENTUM BUILDING FOR NOVEL VAZALORE® LIQUID-FILLED ASPIRIN CAPSULES

For Immediate Release PLx Pharma Inc. Reports Fourth Quarter and Full Year 2021 Results and Provides Business Update MOMENTUM BUILDING FOR NOVEL VAZALORE? LIQUID-FILLED ASPIRIN CAPSULES ? Total Net Sales of $8.2 Million in Last Five Months of 2021 ? Net Sales of $1.6 Million in the Fourth Quarter 2021, Reflecting Timing of Trade Re-Orders Following Strong Initial Sales Distribution of VAZALORE in

March 11, 2022 EX-21.1

Subsidiaries of the Company.*

Exhibit 21.1 Subsidiaries of PLx Pharma Inc. 1. PLx Opco Inc., organized under the laws of Delaware

February 16, 2022 SC 13G/A

PLXP / PLx Pharma Inc / WHITE ROCK CAPITAL MANAGEMENT LP - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1) PLx Pharma Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 72942A107 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pur

February 14, 2022 SC 13G/A

PLXP / PLx Pharma Inc / Rosalind Advisors, Inc. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A (Amendment No. 2) Under the Securities Exchange Act of 1934 PLx Pharma Inc. (Name of Issuer) Common Shares (Title of Class of Securities) 72942A107 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Sched

February 14, 2022 EX-99.A

Joint Filing Agreement

EX-99.A 2 exa.htm EXHIBIT A Exhibit A Joint Filing Agreement The undersigned hereby agree that this Statement on Schedule 13G/A with respect to the beneficial ownership of shares of Common Stock of PLx Pharma Inc. is filed jointly, on behalf of each of them. Rosalind Advisors, Inc. By: /s/ Steven Salamon Name: Steven Salamon Title: President Rosalind Master Fund L.P. By: /s/ Mike McDonald Name: Mi

February 11, 2022 SC 13G/A

PLXP / PLx Pharma Inc / Level One Partners, LLC - SCHEDULE 13G Passive Investment

begin 644 schedule13g.pdf M)5!$1BTQ+C,-)?\-,2 P(&]B:@T\/ TO5&ET;&4@*/[ ', 8P!H &4 M9 !U &P 90 Q #, 9P N &0 ;P!C '@I#2]0PR+XJTX#^G5S2]A@ M==OR^'HRJS$^B7Q9?C/&N#1\&B&-F,:6QIX&IG$NSRYJ[JSFZ/NUK'&C-7Y? M'G^? .,*84G*'W\N9K5VK\IB$TK65!%MC]9Q*;:)/33W5G3>VSR8,H=Y#M(# ML'F(.A\H"*(0E,)S&44P:KMV%#%:T@L4@)K75A3K$.(:^# D*>0'TC60,I M,D 6INA"L!I-N2+$>WUVE@#4L 6]#4.TT*R"F; M'+;)85L68X?+,X$/SR>C[#G+<8#.^2-4> D[?:2

February 11, 2022 SC 13G/A

PLXP / PLx Pharma Inc / Level One Partners, LLC - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* PLx Pharma Inc. - (Name of Issuer) Common Stock, $0.001 par value - (Title of Class of Securities) 72942A107 - (CUSIP Number) December 31, 2021 - (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule purs

November 22, 2021 S-8

As filed with the Securities and Exchange Commission on November 22, 2021

S-8 1 s81157701611192021.htm As filed with the Securities and Exchange Commission on November 22, 2021 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 PLX PHARMA INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation or organizat

November 12, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 9, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File N

November 12, 2021 EX-99.1

PLx Pharma Inc. Reports Third Quarter 2021 Results and Provides Business Update -- Results demonstrate strong execution of initial phase of VAZALORE commercial launch, including shipments to 30,000+ stores nationwide and e-commerce sites -- -- Report

For Immediate Release PLx Pharma Inc. Reports Third Quarter 2021 Results and Provides Business Update - Results demonstrate strong execution of initial phase of VAZALORE commercial launch, including shipments to 30,000+ stores nationwide and e-commerce sites - - Reported net revenue of $6.6 million in third quarter 2021 reflecting initial sales of VAZALORE - - Third quarter 2021 net loss was ($0.8

November 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ? Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended September 30, 2021 Or ? Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 Commission File Number 001-36351 P

October 5, 2021 DEF 14A

PLx Pharma Inc. 2018 Incentive Plan, as amended, incorporated by reference to Annex A of the Company’s Definitive Proxy Statement on Schedule 14A, SEC File No. 001-36351, filed on October 5, 2021.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

September 21, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 21, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File

September 21, 2021 8-K

8-K

August 13, 2021 CORRESP

PLx Pharma Inc. 9 Fishers Lane, Ste. E Sparta, New Jersey 07871 August 13, 2021

PLx Pharma Inc. 9 Fishers Lane, Ste. E Sparta, New Jersey 07871 August 13, 2021 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E., Mail Stop 4546 Washington, D.C. 20549-4546 Attention: Jordan Nimitz Re: PLx Pharma Inc. Registration Statement on Form S-3 Filed August 6, 2021 File No. 333-258540 Ladies and Gentlemen:

August 6, 2021 EX-1.2

Equity Distribution Agreement, dated August 6, 2021, by and between the Company and JMP Securities LLC (filed as Exhibit 1.2 to the Registration Statement on Form S-3 (File No. 333-333-258540), filed with the SEC on August 6, 2021, and incorporated herein by reference).

Exhibit 1.2 PLx Pharma Inc. Common Stock EQUITY DISTRIBUTION AGREEMENT Dated: August 6, 2021 TABLE OF CONTENTS SECTION 1. Description of Securities. SECTION 2. Placements. SECTION 3. Sale of Placement Securities by the Placement Agent SECTION 4. Suspension of Sales SECTION 5. Representations and Warranties. SECTION 6. Sale and Delivery to the Placement Agent; Settlement. SECTION 7. Covenants of th

August 6, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 6, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

August 6, 2021 S-3

As filed with the Securities and Exchange Commission on August 6, 2021

As filed with the Securities and Exchange Commission on August 6, 2021 Registration No.

August 6, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ? Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 30, 2021 Or ? Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 Commission File Number 001-36351 PLx Ph

August 6, 2021 EX-10.1

Second Amendment to Employment Agreement, dated August 3, 2021, by and between the Company and Rita O’Connor.*

Exhibit 10.1 SECOND AMENDMENT TO EMPLOYMENT AGREEMENT This SECOND AMENDMENT TO EMPLOYMENT AGREEMENT (the ?Second Amendment?) is made and entered into as of August 3, 2021, by and between Rita O?Connor (the ?Executive?) and PLx Pharma Inc., a Delaware corporation (the ?Company?) for the purpose of amending that one certain Employment Agreement, dated May 1, 2017, by and between the parties, as prev

August 6, 2021 EX-4.3

Form of Indenture.

Exhibit 4.3 PLX PHARMA INC. Issuer AND as Trustee INDENTURE Dated as of , 20 Debt Securities CROSS-REFERENCE TABLE(1) SECTION OF TRUST INDENTURE ACT OF 1939, AS AMENDED SECTION(S) OF INDENTURE 310(a) 7.9 310(b) 7.8 311(a) 7.13 311(b) 7.13 312(a) 5.1, 5.2(a) 312(b) 5.2(b) 312(c) 5.2(c) 313(a) 5.4 313(b) 5.4 313(c) 5.4 313(d) 5.4 314(a) 5.3, 14.12 314(c) 14.7(a) 314(e) 14.7(b) 315(a) 7.1 315(b) 7.14

August 6, 2021 EX-99.1

PLx Pharma Inc. Reports Second Quarter 2021 Results and Provides Business Update -- Walmart, Walgreens, Rite Aid, CVS and many other retailers placing VAZALORE on shelves later this month-- --VAZALORE launch inventory manufactured and currently shipp

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Reports Second Quarter 2021 Results and Provides Business Update - Walmart, Walgreens, Rite Aid, CVS and many other retailers placing VAZALORE on shelves later this month- -VAZALORE launch inventory manufactured and currently shipping to retailers across the country- Sparta, New Jersey, August 6, 2021 ? PLx Pharma Inc. (NASDAQ: PLXP) (?PLx? or the

August 6, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 6, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Num

June 11, 2021 SC 13D/A

PLXP / PLx Pharma Inc / Park West Asset Management LLC - AMENDMENT NO. 4 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

June 11, 2021 EX-1

SALES AGENCY AGREEMENT

SALES AGENCY AGREEMENT June 7, 2021 RAYMOND JAMES & ASSOCIATES, INC. 880 Carillon Parkway St. Petersburg, Florida 33716 Dear Sir or Madam: This agreement (this ?Agreement?) sets forth the terms and conditions upon which Park West Investors Master Fund, Limited (?PWIMF?), a Cayman Islands exempted company and Park West Partners International, Limited, a Cayman Islands exempted company (?PWPI? and,

June 11, 2021 424B3

2,580,644 SHARES PLX PHARMA INC. Common Stock ($0.001 par value)

Filed Pursuant to Rule 424(b)(3) Registration No. 333-239547 PROSPECTUS 2,580,644 SHARES PLX PHARMA INC. Common Stock ($0.001 par value) This prospectus relates to the resale of up to 2,580,644 shares of PLx Pharma Inc. (the ?Company,? ?we,? ?our? or ?us?) common stock by the selling stockholders listed in this prospectus or their permitted transferees. The shares of common stock being offered by

June 11, 2021 424B3

5,769,230 SHARES PLX PHARMA INC. Common Stock ($0.001 par value)

Filed Pursuant to Rule 424(b)(3) Registration No. 333-230550 PROSPECTUS 5,769,230 SHARES PLX PHARMA INC. Common Stock ($0.001 par value) This prospectus relates to the resale of up to 5,769,230 shares of PLx Pharma Inc. (the ?Company,? ?we,? ?our? or ?us?) common stock by the selling stockholders listed in this prospectus or their permitted transferees. The shares of common stock being offered by

May 14, 2021 EX-99.1

PLx Pharma Inc. Reports First Quarter 2021 Results and Provides Business Update -- VAZALORE 325 mg and 81 mg, the first-ever novel, liquid-filled aspirin capsules, gain FDA approval ? -- Company secured $71.4 million of gross proceeds in an underwrit

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Reports First Quarter 2021 Results and Provides Business Update - VAZALORE 325 mg and 81 mg, the first-ever novel, liquid-filled aspirin capsules, gain FDA approval ? - Company secured $71.4 million of gross proceeds in an underwritten public offering of common stock for the launch of VAZALORE ? - VAZALORE?s U.S. commercial launch on track for thi

May 14, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 14, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Numbe

May 14, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ? Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended March 31, 2021 Or ? Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 Commission File Number 001-36351 PLx P

April 30, 2021 10-K/A

Annual Report - FORM 10-K/A

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

March 17, 2021 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 16, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

March 16, 2021 SC 13G

SCHEDULE 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* PLx Pharma Inc. - (Name of Issuer) Common Stock, $0.001 par value - (Title of Class of Securities) 72942A107 - (CUSIP Number) November 18, 2020 - (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursu

March 12, 2021 EX-4.6

Description of Registered Securities.*

Exhibit 4.6 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 PLx Pharma Inc. (the ?Company?) has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the ?Exchange Act?): its common stock, par value $0.001 per share (?Common Stock?). The following is a summary of the material terms

March 12, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 12, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

March 12, 2021 10-K

Annual Report - FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ? Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2020 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-36351 PLx phar

March 12, 2021 EX-99.1

PLx Pharma Inc. Reports Fourth Quarter and Full Year 2020 Results and Provides Business Update -- Received FDA approval of sNDAs for both VAZALORE 325 mg and 81 mg, the first-ever novel, liquid-filled aspirin capsule -- -- U.S. commercial launch of V

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Reports Fourth Quarter and Full Year 2020 Results and Provides Business Update - Received FDA approval of sNDAs for both VAZALORE 325 mg and 81 mg, the first-ever novel, liquid-filled aspirin capsule - - U.S. commercial launch of VAZALORE planned for third quarter 2021 - - Secured $63 million of gross proceeds in an underwritten public offering of

March 12, 2021 EX-21.1

Subsidiaries of the Company.*

Exhibit 21.1 Subsidiaries of PLx Pharma Inc. 1. PLx Opco Inc., organized under the laws of Delaware

March 4, 2021 424B5

Shares of Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333- 230478 Prospectus Supplement (To Prospectus Dated April 4, 2019) Shares of Common Stock We are offering 7,875,000 shares of our common stock, par value $0.001 per share. Our common stock is listed on the Nasdaq Capital Market under the symbol “PLXP.” On March 1, 2021, the last reported sale price of our common stock on the Nasdaq Capital Marke

March 3, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 3, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Numb

March 3, 2021 EX-99.1

PLX PHARMA INC. PRICES $63 MILLION UNDERWRITTEN PUBLIC OFFERING OF COMMON STOCK

Exhibit 99.1 For Immediate Release PLX PHARMA INC. PRICES $63 MILLION UNDERWRITTEN PUBLIC OFFERING OF COMMON STOCK Sparta, New Jersey (March 3, 2021) - PLx Pharma Inc. (NASDAQ: PLXP) (?PLx? or the ?Company?), a late-stage specialty pharmaceutical company focused on its clinically-validated and patent-protected PLxGuard? drug delivery platform designed to provide more effective and safer products,

March 3, 2021 EX-1.1

Underwriting Agreement, dated March 3, 2021, between the Company and Raymond James & Associates, Inc., as representative of the several underwriters listed on Schedule I thereto (incorporate by reference to Exhibit 1.1 to the Company Current Report on Form 8-K filed on March 3, 2021 (File No. 001-36351)).

Exhibit 1.1 7,875,000 Shares1 PLx Pharma Inc. Common Stock UNDERWRITING AGREEMENT St. Petersburg, Florida March 3, 2021 Raymond James & Associates, Inc. As Representative of the Several Underwriters listed on Schedule I hereto 880 Carillon Parkway St. Petersburg, Florida 33716 Ladies and Gentlemen: PLx Pharma Inc., a Delaware corporation (the ?Company?), proposes, subject to the terms and conditio

March 2, 2021 EX-99.1

PLX PHARMA INC. ANNOUNCES PROPOSED PUBLIC OFFERING OF COMMON STOCK

Exhibit 99.1 For Immediate Release PLX PHARMA INC. ANNOUNCES PROPOSED PUBLIC OFFERING OF COMMON STOCK Sparta, New Jersey, March 2, 2021 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company focused on its clinically-validated and patent-protected PLxGuard™ drug delivery platform designed to provide more effective and safer products, announced toda

March 2, 2021 EX-10.1

Termination of Equity Distribution Agreement, dated as of March 2, 2021, between the Company and JMP Securities LLC (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on March 2, 2021 (File No. 001-36351)).

Exhibit 10.1 TERMINATION OF EQUITY DISTRIBUTION AGREEMENT This Termination of Equity Distribution Agreement (this ?Agreement?), dated as of March 2, 2021, is made by and between PLx Pharma Inc. (the ?Company?), and JMP Securities LLC (?JMP,? and, together with the Company, each a ?Party? and collectively, the ?Parties?). WHEREAS, JMP and the Company are party to that certain Equity Distribution Ag

March 2, 2021 424B5

SUBJECT TO COMPLETION, DATED MARCH 2, 2021

Filed Pursuant to Rule 424(b)(5) Registration No. 333- 230478 The information in this preliminary prospectus supplement is not complete and may be changed. This preliminary prospectus supplement and the accompanying prospectus are part of an effective registration statement filed with the Securities and Exchange Commission under the Securities Act of 1933. This preliminary prospectus supplement an

March 2, 2021 8-K

Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 2, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Numb

March 1, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 1, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File Numb

March 1, 2021 EX-99.2

PLx Pharma Receives FDA Approval of SNDAs for Both VAZALORE 325 mg and 81 mg -- VAZALORE is the first ever liquid-filled aspirin capsule with an innovative delivery platform indicated as a pain reliever, fever reducer and for aspirin therapy in vascu

Exhibit 99.2 For Immediate Release PLx Pharma Receives FDA Approval of SNDAs for Both VAZALORE 325 mg and 81 mg - VAZALORE is the first ever liquid-filled aspirin capsule with an innovative delivery platform indicated as a pain reliever, fever reducer and for aspirin therapy in vascular indications ? - U.S. commercial launch of VAZALORE planned for third quarter 2021 - Sparta, New Jersey, March 1,

March 1, 2021 8-K

Current Report

begin 644 e620335ex99-1.pdf M)5!$1BTQ+C<-"B6UM;6U#0HQ(# @;V)J#0H\/"]4>7!E+T-A=&%L;V7!E+U!A9V4O4&%R96YT(#(@,"!2+U)E M'0O26UA9V5"+TEM86=E0R]);6%G94E=(#X^+TUE9&EA M0F]X6R P(# @-S(P(#0P-5T@+T-O;G1E;G1S(#0@,"!2+T=R;W5P/#PO5'EP M92]'<"]3+U1R86YS<&%R96YC>2]#4R]$979I8V521T(^/B]486)S+U,O M4W1R=6-T4&%R96YT#3>L8[ MWV,^)^/&;=?ERL'D>@I/<<2!,^Z?#+668 4'Q34T51S]/(-]'"67MQHVSW&$ ML#E^+;G&=/#U^BR.OL<1S/W8Y!5(>PFYE

January 22, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A (Amendment No. 1) Under the Securities Exchange Act of 1934 PLx Pharma Inc. (Name of Issuer) Common Shares (Title of Class of Securities) (CUSIP Number) December 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A (Amendment No. 1) Under the Securities Exchange Act of 1934 PLx Pharma Inc. (Name of Issuer) Common Shares (Title of Class of Securities) 72942A107 (CUSIP Number) December 31, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Sched

January 22, 2021 EX-99.A

Joint Filing Agreement

Exhibit A Joint Filing Agreement The undersigned hereby agree that this Statement on Schedule 13G with respect to the beneficial ownership of shares of Common Stock of PLx Pharma Inc.

January 11, 2021 8-K

Financial Statements and Exhibits, Other Events -

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 11, 2021 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File N

January 11, 2021 EX-99.1

PLx Pharma, Inc.

EX-99.1 2 ex991to8k1157700201112021.htm Exhibit 99.1 Case #6912 (12/14/2020) PLx Pharma, Inc. Vazalore Challenger: Bayer HealthCare LLC Product Type: Drugs/Health/Health Aids Issues: Superiority Claims; Health & Safety Claims; Comparative Performance Claims Disposition: Modified/Discontinued - Competent and reliable scientific evidence must, in addition to achieving statistical significance, also

January 8, 2021 424B4

9,986,283 Shares PLX PHARMA INC. Common Stock ($0.001 par value)

Filed Pursuant to Rule 424(b)(4) Registration Statement No. 333-251554 PROSPECTUS 9,986,283 Shares PLX PHARMA INC. Common Stock ($0.001 par value) This prospectus relates to the resale of up to 9,986,283 shares of PLx Pharma Inc. (the “Company,” “we,” “our” or “us”) common stock, which includes 5,230,910 shares of our common stock issuable upon the exercise of outstanding warrants, which are held

January 4, 2021 CORRESP

-

PLx Pharma Inc. 9 Fishers Lane, Ste. E Sparta, New Jersey 07871 January 4, 2021 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Alan Campbell Re: PLx Pharma Inc. Registration Statement on Form S-3 Filed December 21, 2020 File No. 333-251554 Ladies and Gentlemen: The undersigned Registrant under the abov

December 21, 2020 S-3

-

As filed with the Securities and Exchange Commission on December 21, 2020 Registration Statement No.

December 18, 2020 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 PLx Pharma Inc. (Name of Issuer) Common Shares (Title of Class of Securities) (CUSIP Number) November 16, 2020 (Date of Eve

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 PLx Pharma Inc. (Name of Issuer) Common Shares (Title of Class of Securities) 72942A107 (CUSIP Number) November 16, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: o Rule

December 18, 2020 EX-99.A

Joint Filing Agreement

Exhibit A Joint Filing Agreement The undersigned hereby agree that this Statement on Schedule 13G with respect to the beneficial ownership of shares of Common Stock of PLx Pharma Inc.

December 16, 2020 EX-99.1

Joint Filing Agreement

Exhibit 99.1 Joint Filing Agreement In accordance with Rule 13d-1(k) promulgated under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree to the joint filing with all other Reporting Persons (as such term is defined in the Schedule 13G referred to below) on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the shares of

December 16, 2020 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ) PLx Pharma Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 7

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ) PLx Pharma Inc. (Name of Issuer) Common Stock, $0.001 Par Value Per Share (Title of Class of Securities) 72942A107 (CUSIP Number) November 16, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule purs

November 30, 2020 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 30, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File

November 16, 2020 EX-4.1

Form of Warrant to Purchase Common Stock issued by PLx Pharma Inc. in connection with the Securities Purchase Agreement among PLx Pharma Inc. and the investors set forth on the signature pages thereto, dated as of November 16, 2020 (incorporated by reference to Exhibit 4.1 to the Company’s Current Report on Form 8-K filed on November 16, 2020).

Exhibit 4.1 [FORM OF WARRANT] NEITHER THE ISSUANCE AND SALE OF THE SECURITIES REPRESENTED BY THIS INSTRUMENT NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED (I) IN THE ABSENCE OF (A) AN EFFECTIVE

November 16, 2020 EX-10.2

Form of Registration Rights Agreement, dated November 16, 2020, by and among the Company and the Investors set forth on the signature page thereto (incorporated by reference to Exhibit 10.2 to the Company’s Current Report on Form 8-K filed on November 18, 2020 (File No. 001-36351)).

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is made and entered into as of November [●], 2020, by and among PLx Pharma Inc., a Delaware corporation (the “Company”), and the purchasers set forth on Schedule 1 hereto (each, a “Purchaser”, and collectively, the “Purchasers”), and shall become effective as of the Closing (as defined in the Purchase

November 16, 2020 EX-10.3

Placement Agency Agreement, dated November 16, 2020, by and between the Company and Raymond James & Associates, Inc. (incorporated by reference to Exhibit 10.3 to the Company’s Current Report on Form 8-K filed on November 16, 2020 (File No. 001-36351)).

Exhibit 10.3 PLACEMENT AGENCY AGREEMENT November 16, 2020 Raymond James & Associates, Inc. 277 Park Avenue, Suite 410 New York, New York 10172 Ladies and Gentlemen: PLx Pharma Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions of this Placement Agency Agreement (the “Agreement”) and the Purchase Agreement (defined below), to issue and sell to certain invest

November 16, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 10, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or other Jurisdiction of Incorporation) (Commission File

November 16, 2020 EX-99.1

PLx Pharma Inc. Reports Third Quarter 2020 Results and Provides Business Update --Announces $18 million private placement-- --Submitted sNDAs for VAZALORE 325 mg and 81 mg doses to FDA end of October-- --On target for third quarter 2021 commercial la

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Reports Third Quarter 2020 Results and Provides Business Update -Announces $18 million private placement- -Submitted sNDAs for VAZALORE 325 mg and 81 mg doses to FDA end of October- -On target for third quarter 2021 commercial launch of VAZALORE- Sparta, New Jersey, November 16, 2020 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a lat

November 16, 2020 EX-99.2

PLx Pharma Inc. Submits Supplemental New Drug Applications for VAZALORE™ 325 mg and 81 mg to U.S. Food and Drug Administration -- FDA sets estimated completion review date for the end of February 2021 -- -- Targeting launch of VAZALORE for third quar

Exhibit 99.2 For Immediate Release PLx Pharma Inc. Submits Supplemental New Drug Applications for VAZALORE™ 325 mg and 81 mg to U.S. Food and Drug Administration - FDA sets estimated completion review date for the end of February 2021 - - Targeting launch of VAZALORE for third quarter 2021 – Sparta, New Jersey, November 16, 2020 — PLx Pharma Inc. (NASDAQ: PLXP), a late-stage specialty pharmaceutic

November 16, 2020 EX-10.1

Form of Securities Purchase Agreement, dated November 16, 2020, by and among the Company and the Investors set forth on the signature pages thereto (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on November 18, 2020 (File No. 001-36351)).

SECURITIES PURCHASE AGREEMENT THIS SECURITIES PURCHASE AGREEMENT (the “Agreement”), dated as of November 16, 2020, by and among PLx Pharma Inc.

November 13, 2020 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended September 30, 2020 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 Commission File Number 001-36351 P

October 30, 2020 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing -

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): October 27, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File N

September 25, 2020 DEF 14A

PLx Pharma Inc. 2018 Incentive Plan, as amended (incorporated herein by reference to the Annex A of the Company’s Definitive Proxy Statement on Schedule 14A filed on September 25, 2020)(File No. 001-36351)).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confide

September 22, 2020 8-K

PLx Pharma Inc. September 2020 Corporate Presentation.

September 22, 2020 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 22, 2020

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 22, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File

August 14, 2020 EX-99.1

PLx Pharma Inc. Reports Second Quarter 2020 Results and Provides Business Update --Shifting the date of sNDA filings for VAZALORE 325 mg and 81 mg doses earlier to mid-November 2020-- --Targeting launch of VAZALORE 325 mg and 81 mg for third quarter

EX-99.1 2 ex991to8k1157700208142020.htm Exhibit 99.1 PLx Pharma Inc. Reports Second Quarter 2020 Results and Provides Business Update -Bioequivalence study of VAZALORE 325 mg on track with top-line data demonstrating bioequivalence to immediate release aspirin- -Shifting the date of sNDA filings for VAZALORE 325 mg and 81 mg doses earlier to mid-November 2020- -Targeting launch of VAZALORE 325 mg

August 14, 2020 10-Q

Quarterly Report - FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 30, 2020 For the Quarterly Period Ended June 30, 2020 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-

August 14, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition, Shareholder Director Nominations

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 14, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Nu

July 6, 2020 CORRESP

-

PLx Pharma Inc. 9 Fishers Lane, Ste. E Sparta, New Jersey 07871 July 6, 2020 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Alan Campbell Re: PLx Pharma Inc. Registration Statement on Form S-3 Filed June 30, 2020 File No. 333-239547 Ladies and Gentlemen: The undersigned Registrant under the above-refer

June 30, 2020 S-3

-

As filed with the Securities and Exchange Commission on June 29, 2020 Registration No.

May 26, 2020 SC 13G

DPRX / Dipexium Pharmaceuticals, Inc. / MSD Partners, L.P. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. )* PLx Pharma Inc. (Name of Issuer) Common Stock, $.001 par value per share (Title of Class of Securities) 72942A107 (CUSIP Number) May 15, 2020 (Date of Even

May 20, 2020 SC 13D/A

DPRX / Dipexium Pharmaceuticals, Inc. / Park West Asset Management LLC - AMENDMENT NO. 3 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

May 18, 2020 EX-3.1

Certificate of Designations, Preferences and Rights of Series B Convertible Preferred Stock of the Company (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K filed on May 18, 2020 (File No. 001-36351)).

Exhibit 3.1 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES B CONVERTIBLE PREFERRED STOCK OF PLX PHARMA INC. (Pursuant to Section 151 of the Delaware General Corporation Law) PLx Pharma Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), hereby certifies that, pursuant to authority vested in the Board of Directors of the Company (the “B

May 18, 2020 EX-99.1

PLx Pharma Inc. Announces Completion of $8 Million Convertible Preferred Stock Financing

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Announces Completion of $8 Million Convertible Preferred Stock Financing SPARTA, N.J., May 18, 2020 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company initially focused on developing its clinically validated and patent-protected PLxGuard™ delivery system to provide more effective and safer prod

May 18, 2020 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Financial Statements and Exhibits, Other Events, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 15, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Numbe

May 15, 2020 EX-99.1

PLx Pharma Inc. Reports First Quarter 2020 Results -- Company to begin bioequivalence study of VAZALORE 325 mg dose -- -- sNDA submissions expected by year-end --

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Reports First Quarter 2020 Results - Company to begin bioequivalence study of VAZALORE 325 mg dose - - sNDA submissions expected by year-end - Sparta, New Jersey, May 15, 2020 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company initially focused on developing its clinically validated and patent-

May 15, 2020 10-Q

Quarterly Report - FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended March 31, 2020 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of registr

May 15, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 15, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Numbe

May 4, 2020 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 28, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

April 24, 2020 10-K/A

Annual Report - FORM 10-K/A

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) ☒ Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2019 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

April 23, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 22, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

April 7, 2020 DEF 14A

DPRX / Dipexium Pharmaceuticals, Inc. DEF 14A - -

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confide

March 20, 2020 PRE 14A

DPRX / Dipexium Pharmaceuticals, Inc. PRE 14A - -

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confide

March 13, 2020 EX-4.2

Form of Warrant.

Exhibit 4.2 THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND, ACCORDINGLY, MAY NOT BE TRANSFERRED UNLESS (I) SUCH SECURITIES HAVE BEEN REGISTERED FOR SALE PURSUANT TO THE SECURITIES ACT OF 1933, AS AMENDED,

March 13, 2020 DEFA14A

DPRX / Dipexium Pharmaceuticals, Inc. DEFA14A - -

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 12, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

March 13, 2020 EX-99.1

PLx Pharma Inc. Reports Fourth Quarter 2019 Results and Provides Regulatory Update on VAZALORE -- Planning a Bioequivalence Study to Support VAZALORE 325 mg sNDA -- -- Announces $8 Million Convertible Preferred Stock Financing with Park West and MSD

Exhibit 99.1 PLx Pharma Inc. Reports Fourth Quarter 2019 Results and Provides Regulatory Update on VAZALORE - Planning a Bioequivalence Study to Support VAZALORE 325 mg sNDA - - Announces $8 Million Convertible Preferred Stock Financing with Park West and MSD Partners - Sparta, New Jersey, March 13, 2020 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutic

March 13, 2020 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 12, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

March 13, 2020 EX-10.1

Purchase Agreement, dated as of March 12, 2020, by and among the Company and the investors set forth on the signature pages thereto.

Exhibit 10.1 EXECUTION VERSION PURCHASE AGREEMENT THIS PURCHASE AGREEMENT (“Agreement”) is made as of the 12th day of March, 2020 by and among PLx Pharma Inc., a Delaware corporation (the “Company”), and the Investors set forth on the signature pages affixed hereto (each an “Investor” and collectively the “Investors”). Recitals A. The Company and the Investors are executing and delivering this Agr

March 13, 2020 EX-10.2

Registration Rights Agreement, dated as of March 12, 2020, by and among the Company and the Investors named in that certain Purchase Agreement by and among the Company and the Investors (incorporated by reference to Exhibit 10.2 to the Company’s Current Report on Form 8-K, filed on March 13, 2020)(File No. 001-36351)).

Exhibit 10.2 EXECUTION VERSION REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the “Agreement”) is made and entered into as of this 12th day of March, 2020 by and among PLx Pharma Inc., a Delaware corporation (the “Company”), and the “Investors” named in that certain Purchase Agreement by and among the Company and the Investors (the “Purchase Agreement”). Capitalized terms used h

March 13, 2020 EX-10.2

Registration Rights Agreement, dated as of March 12, 2020, by and among the Company and the investors set forth on the signature pages thereto.

Exhibit 10.2 EXECUTION VERSION REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the “Agreement”) is made and entered into as of this 12th day of March, 2020 by and among PLx Pharma Inc., a Delaware corporation (the “Company”), and the “Investors” named in that certain Purchase Agreement by and among the Company and the Investors (the “Purchase Agreement”). Capitalized terms used h

March 13, 2020 EX-4.1

Form of Certificate of Designations, Preferences and Rights of Series B Convertible Preferred Stock.

Exhibit 4.1 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES B CONVERTIBLE PREFERRED STOCK OF PLX PHARMA INC. (Pursuant to Section 151 of the Delaware General Corporation Law) PLx Pharma Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), hereby certifies that, pursuant to authority vested in the Board of Directors of the Company (the “B

March 13, 2020 EX-4.1

Form of Certificate of Designations, Preferences and Rights of Series B Convertible Preferred Stock.

Exhibit 4.1 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES B CONVERTIBLE PREFERRED STOCK OF PLX PHARMA INC. (Pursuant to Section 151 of the Delaware General Corporation Law) PLx Pharma Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), hereby certifies that, pursuant to authority vested in the Board of Directors of the Company (the “B

March 13, 2020 EX-4.2

Form of Warrant.

Exhibit 4.2 THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND, ACCORDINGLY, MAY NOT BE TRANSFERRED UNLESS (I) SUCH SECURITIES HAVE BEEN REGISTERED FOR SALE PURSUANT TO THE SECURITIES ACT OF 1933, AS AMENDED,

March 13, 2020 EX-99.1

Press Release, dated March 13, 2020.

Exhibit 99.1 PLx Pharma Inc. Reports Fourth Quarter 2019 Results and Provides Regulatory Update on VAZALORE - Planning a Bioequivalence Study to Support VAZALORE 325 mg sNDA - - Announces $8 Million Convertible Preferred Stock Financing with Park West and MSD Partners - Sparta, New Jersey, March 13, 2020 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutic

March 13, 2020 10-K

DPRX / Dipexium Pharmaceuticals, Inc. 10-K - Annual Report - FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2019 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-36351 PLx phar

March 13, 2020 EX-10.1

Purchase Agreement, dated as of March 12, 2020, by and among the Company and the investors set forth on the signature pages thereto.

Exhibit 10.1 EXECUTION VERSION PURCHASE AGREEMENT THIS PURCHASE AGREEMENT (“Agreement”) is made as of the 12th day of March, 2020 by and among PLx Pharma Inc., a Delaware corporation (the “Company”), and the Investors set forth on the signature pages affixed hereto (each an “Investor” and collectively the “Investors”). Recitals A. The Company and the Investors are executing and delivering this Agr

March 13, 2020 EX-21.1

Subsidiaries of the Company.*

Exhibit 21.1 Subsidiaries of PLx Pharma Inc. 1. PLx Opco Inc., organized under the laws of Delaware 2. PLx Chile SpA, organized under the laws of Chile

March 13, 2020 EX-4.4

Description of Registered Securities.*

Exhibit 4.4 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 PLx Pharma Inc. (the “Company”) has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”): its common stock, par value $0.001 per share (“Common Stock”). The following is a summary of the material terms

January 13, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

8-K 1 form8k1157700201132020.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 13, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of

January 13, 2020 EX-99.1

Corporate Presentation Nasdaq: PLXP Confidential

Exhibit 99.1 Corporate Presentation Nasdaq: PLXP Confidential Confidential 2 Forward - Looking Statements This presentation includes or incorporates by reference statements that constitute forward - looking statements within the meaning of Section 27 A of the Securities Act of 1933 , as amended, and Section 21 E of the Securities Exchange Act of 1934 , as amended . These statements relate to futur

January 6, 2020 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 6, 2020 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Nu

January 6, 2020 EX-99.1

PLx Pharma Inc. Provides Regulatory Update on VAZALORE -- PLx Aligning with the FDA on Data Requirements for VAZALORE --FDA Approves Labeling for 325 mg -- -- Expect to Launch VAZALORE in late 2020 --

Exhibit 99.1 PLx Pharma Inc. Provides Regulatory Update on VAZALORE - PLx Aligning with the FDA on Data Requirements for VAZALORE -FDA Approves Labeling for 325 mg - - Expect to Launch VAZALORE in late 2020 - Sparta, New Jersey, January 6, 2020 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company initially focused on developing its clinically val

November 8, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): November 8, 2019 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File N

November 8, 2019 EX-99.1

PLx Pharma Inc. Reports Third Quarter 2019 Results --Company on track for sNDA submission to the FDA by year-end--

EX-99.1 2 ex991to8k1157700211082019.htm Exhibit 99.1 PLx Pharma Inc. Reports Third Quarter 2019 Results -Company on track for sNDA submission to the FDA by year-end- Sparta, New Jersey, November 8, 2019 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company initially focused on developing its clinically validated and patent-protected PLxGuard™ deli

November 8, 2019 10-Q

PLXP / PLx Pharma Inc. 10-Q - Quarterly Report - FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended September 30, 2019 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of reg

August 19, 2019 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 15, 2019 PLx Pharma Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Nu

August 9, 2019 10-Q

PLXP / PLx Pharma Inc. 10-Q - Quarterly Report - FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 30, 2019 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of registra

August 9, 2019 EX-10.1

Manufacturing Services Agreement, dated June 28, 2019, between the Company and Patheon Pharmaceuticals Inc. (incorporated by reference to Exhibit 10.1 to the Company’s Quarterly Report on Form 10-Q filed on August 9, 2019 (File No. 001-36351)).+

Exhibit 10.1 17 CFR 240.24b-2, confidential information has been omitted in places marked “[***]” and has been filed separately with the Securities and Exchange Commission pursuant to a Confidential Treatment Application filed with the Commission. Manufacturing Services Agreement Effective Date: June 28, 2019 PARTIES PATHEON PHARMACEUTICALS INC. a corporation existing under the laws of the State o

July 2, 2019 DEF 14A

PLXP / PLx Pharma Inc. DEF 14A - -

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confide

May 10, 2019 10-Q

PLXP / PLx Pharma Inc. 10-Q Quarterly Report FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended March 31, 2019 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of registr

April 3, 2019 CORRESP

PLXP / PLx Pharma Inc. CORRESP

JMP Securities LLC 600 Montgomery Street, Suite 1100 San Francisco, California 94111 April 3, 2019 Via EDGAR transmission and Facsimile U.

April 2, 2019 CORRESP

PLXP / PLx Pharma Inc. CORRESP

PLx Pharma Inc. 8285 El Rio Street, Suite 130 Houston, Texas 77054 April 2, 2019 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Mail Stop 4720 100 F Street, N.E. Washington, D.C. 20549 Attention: Sonia Bednarowski Re: PLx Pharma Inc. Registration Statement on Form S-3 Filed March 25, 2019 File No. 333-230478 Ladies and Gentlemen: The undersigned Registra

April 2, 2019 10-K/A

PLXP / PLx Pharma Inc. FORM 10-K/A (Annual Report)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) ☒ Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2018 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

April 2, 2019 CORRESP

PLXP / PLx Pharma Inc. CORRESP

PLx Pharma Inc. 8285 El Rio Street, Suite 130 Houston, Texas 77054 April 2, 2019 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Mail Stop 4720 100 F Street, N.E. Washington, D.C. 20549 Attention: Sonia Bednarowski Re: PLx Pharma Inc. Registration Statement on Form S-3 Filed March 27, 2019 File No. 333-230550 Ladies and Gentlemen: The undersigned Registra

March 27, 2019 S-3

PLXP / PLx Pharma Inc.

As filed with the Securities and Exchange Commission on March 27, 2019 Registration No.

March 26, 2019 DEL AM

PLXP / PLx Pharma Inc.

March 26, 2019 VIA EDGAR – FORM DEL AM Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

March 25, 2019 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 25, 2019 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

March 25, 2019 S-3

PLXP / PLx Pharma Inc.

As filed with the Securities and Exchange Commission on March 25, 2019 Registration No.

March 25, 2019 EX-1.2

Equity Distribution Agreement, dated March 25, 2019, by and between the Company and JMP Securities LLC (incorporated by reference to Exhibit 1.2 to the Registration Statement on Form S-3 filed on March 25, 2019 (File No. 333-230478)).

Exhibit 1.2 PLx Pharma Inc. Common Stock EQUITY DISTRIBUTION AGREEMENT Dated: March 25, 2019 TABLE OF CONTENTS SECTION 1. Description of Securities. SECTION 2. Placements. SECTION 3. Sale of Placement Securities by the Placement Agent SECTION 4. Suspension of Sales SECTION 5. Representations and Warranties. SECTION 6. Sale and Delivery to the Placement Agent; Settlement. SECTION 7. Covenants of th

March 25, 2019 EX-4.3

PLX PHARMA INC. as Trustee Dated as of __________, 20__ Debt Securities CROSS-REFERENCE TABLE(1)

Exhibit 4.3 PLX PHARMA INC. Issuer AND as Trustee INDENTURE Dated as of , 20 Debt Securities CROSS-REFERENCE TABLE(1) SECTION OF TRUST INDENTURE ACT OF 1939, AS AMENDED SECTION(S) OF INDENTURE 310(a) 7.9 310(b) 7.8 311(a) 7.13 311(b) 7.13 312(a) 5.1, 5.2(a) 312(b) 5.2(b) 312(c) 5.2(c) 313(a) 5.4 313(b) 5.4 313(c) 5.4 313(d) 5.4 314(a) 5.3, 14.12 314(c) 14.7(a) 314(e) 14.7(b) 315(a) 7.1 315(b) 7.14

March 8, 2019 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 6, 2019 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Numb

March 8, 2019 EX-99.1

PLx Pharma Inc. Reports Fourth Quarter 2018 Results – Company Completes Successful $15 Million Financing –

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Reports Fourth Quarter 2018 Results – Company Completes Successful $15 Million Financing – Houston, Texas, March 8, 2019 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company initially focused on developing its clinically validated and patent-protected PLxGuard™ delivery system to provide more eff

March 8, 2019 EX-21.1

Amendment to Employment Agreement with Efthymios Deliargyris, dated March 7, 2019.*

Exhibit 21.1 Subsidiaries of PLx Pharma Inc. 1. PLx Opco Inc., organized under the laws of Delaware 2. PLx Chile SpA, organized under the laws of Chile

March 8, 2019 10-K

PLXP / PLx Pharma Inc. FORM 10-K (Annual Report)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2018 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-36351 PLx phar

March 8, 2019 EX-10.18

Amendment to Employment Agreement with Natasha Giordano, dated March 7, 2019 (incorporated by reference to Exhibit 10.18 to the Company’s Annual Report on Form 10-K filed on March 8, 2019 (File No. 001-36351)).

Exhibit 10.18 AMENDMENT TO EMPLOYMENT AGREEMENT This AMENDMENT TO EMPLOYMENT AGREEMENT (the “Amendment”) is made and entered into as of March 7, 2019 (the “Effective Date”), by and between Natasha Giordano (the “Executive”) and PLx Pharma Inc., a Delaware corporation (the “Company”), for the purpose of amending that one certain Employment Agreement, dated October 1, 2015 (the “Agreement”), by and

March 8, 2019 EX-10.22

Amendment to Employment Agreement with Michael Valentino, dated March 7, 2019 (incorporated by reference to Exhibit 10.22 to the Company’s Annual Report on Form 10-K filed on March 8, 2019 (File No. 001-36351)).

Exhibit 10.22 AMENDMENT TO AMENDED AND RESTATED EMPLOYMENT AGREEMENT This AMENDMENT TO AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the “Amendment”) is made and entered into as of March 7, 2019 (the “Effective Date”), by and between Michael J. Valentino (the “Executive”) and PLx Pharma Inc., a Delaware corporation (the “Company”), for the purpose of amending that one certain Amended and Restated Emp

March 8, 2019 EX-10.21

Amendment to Employment Agreement with Efthymios Deliargyris, dated March 7, 2019 (incorporated by reference to Exhibit 10.21 to the Company’s Annual Report on Form 10-K filed on March 8, 2019 (File No. 001-36351)).

Exhibit 10.21 AMENDMENT TO EMPLOYMENT AGREEMENT This AMENDMENT TO EMPLOYMENT AGREEMENT (the “Amendment”) is made and entered into as of March 7, 2019 (the “Effective Date”), by and between Efthymios Deliargyris, MD, FACC, FESC, FSCAI (the “Executive”) and PLx Pharma Inc., a Delaware corporation (the “Company”), for the purpose of amending that one certain Employment Agreement, dated August 29, 201

March 8, 2019 EX-10.19

Amendment to Employment Agreement with Rita O’Connor, dated March 7, 2019 (incorporated by reference to Exhibit 10.19 to the Company’s Annual Report on Form 10-K filed on March 8, 2019 (File No. 001-36351)).

Exhibit 10.19 AMENDMENT TO EMPLOYMENT AGREEMENT This AMENDMENT TO EMPLOYMENT AGREEMENT (the “2019 Amendment”) is made and entered into as of March 7, 2019 (the “Effective Date”), by and between Rita O’Connor (the “Executive”) and PLx Pharma Inc., a Delaware corporation (the “Company”), for the purpose of amending that one certain Employment Agreement, dated May 1, 2017 (the “Agreement”), and the A

March 8, 2019 EX-10.20

Amendment to Employment Agreement with Rita O’Connor, dated March 16, 2018 (incorporated by reference to Exhibit 10.20 to the Company’s Annual Report on Form 10-K filed on March 8, 2019 (File No. 001-36351)).

Exhibit 10.20 AMENDMENT TO EMPLOYMENT AGREEMENT This AMENDMENT TO EMPLOYMENT AGREEMENT (the “Amendment”) is made and entered into as of March 16, 2018, by and between Rita O’Connor (the “Executive”) and PLx Pharma Inc., a Delaware corporation (the “Company”) for the purpose of amending that one certain Employment Agreement, dated May 1, 2017, by and between the parties (the “Agreement”). NOW, THER

March 1, 2019 SC 13D/A

DPRX / Dipexium Pharmaceuticals, Inc. / Park West Asset Management LLC - AMENDMENT NO. 2 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 20, 2019 EX-99.1

PLx Pharma Inc. Announces Completion of $15 Million Convertible Preferred Stock Financing

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Announces Completion of $15 Million Convertible Preferred Stock Financing Houston, Texas, February 20, 2019 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company focused on commercializing two patent-protected products, Vazalore™ 325 mg and Vazalore™ 81 mg (referred to together as “Vazalore”™), an

February 20, 2019 EX-3.1

Certificate of Amendment to the Amended Certificate of Incorporation of the Company (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K filed on February 20, 2019 (File No. 001-36351)).

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO THE AMENDED CERTIFICATE OF INCORPORATION OF PLX PHARMA INC. Pursuant to Section 242 of the General Corporation Law of the State of Delaware It is hereby certified that: 1.The name of the corporation is: PLx Pharma Inc. (the “Corporation”). The original Certificate of Incorporation of the Corporation was filed with the Secretary of the State of Delaware on Ja

February 20, 2019 EX-3.2

Certificate of Designations, Preferences and Rights of Series A Convertible Preferred Stock of the Company, incorporated herein by reference to Exhibit 3.2 to the Registrant’s Current Report on Form 8-K, filed on February 20, 2019.

Exhibit 3.2 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES A CONVERTIBLE PREFERRED STOCK OF PLX PHARMA INC. (Pursuant to Section 151 of the Delaware General Corporation Law) PLx Pharma Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), hereby certifies that, pursuant to authority vested in the Board of Directors of the Company by Arti

February 20, 2019 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Financial Statements and Exhibits, Other Events, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 19, 2019 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File

February 20, 2019 EX-3.3

Amended and Restated Certificate of Designations, Preferences and Rights of Series A Convertible Preferred Stock of the Company (incorporated by reference to Exhibit 3.3 to the Company’s Current Report on Form 8-K filed on February 20, 2019 (File No. 001-36351)).

Exhibit 3.3 AMENDED AND RESTATED CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES A CONVERTIBLE PREFERRED STOCK OF PLX PHARMA INC. Pursuant to Section 151 of the Delaware General Corporation Law PLX PHARMA INC., a corporation organized and existing under the laws of the State of Delaware (the “Company”), hereby certifies as follows: FIRST: The name of the corporation is: PLx Pharma In

February 14, 2019 EX-99.1

PLx Pharma Inc. Announces Adjournment of Special Meeting of Stockholders

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Announces Adjournment of Special Meeting of Stockholders Houston, Texas, February 14, 2019 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company focused on commercializing two patent-protected products, Vazalore™ 325 mg and Vazalore™ 81 mg (referred to together as “Vazalore”™), announced today tha

February 14, 2019 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): February 14, 2019 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File

February 13, 2019 DEFA14A

PLXP / PLx Pharma Inc. DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confide

January 10, 2019 DEF 14A

PLXP / PLx Pharma Inc. DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confide

January 7, 2019 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 7, 2019

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 7, 2019 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Nu

January 7, 2019 8-K

8-K

December 31, 2018 SC 13D/A

DPRX / Dipexium Pharmaceuticals, Inc. / Park West Asset Management LLC - PLX PHARMA INC. AMENDMENT NO. 1 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

December 26, 2018 PRE 14A

PLXP / PLx Pharma Inc. PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confide

December 21, 2018 EX-99.1

PLx Pharma Inc. Announces $15 Million Convertible Preferred Stock Financing

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Announces $15 Million Convertible Preferred Stock Financing Houston, Texas, December 20, 2018 — PLx Pharma Inc. (NASDAQ: PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company focused on commercializing two patent-protected products, Vazalore™ 325 mg and Vazalore™ 81 mg (referred to together as “Vazalore”™), announced today

December 21, 2018 EX-10.2

Registration Rights Agreement, dated December 20, 2018, by and among the Company and the Investors set forth on the signature pages thereto (incorporated by reference to Exhibit 10.2 to the Company’s Current Report on Form 8-K filed on December 21, 2018 (File No. 001-36351)).

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the “Agreement”) is made and entered into as of this 20th day of December, 2018 by and among PLx Pharma Inc., a Delaware corporation (the “Company”), and the “Investors” named in that certain Purchase Agreement by and among the Company and the Investors (the “Purchase Agreement”). Capitalized terms used herein have the

December 21, 2018 EX-4.2

Form of Warrant.

Exhibit 4.2 THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND, ACCORDINGLY, MAY NOT BE TRANSFERRED UNLESS (I) SUCH SECURITIES HAVE BEEN REGISTERED FOR SALE PURSUANT TO THE SECURITIES ACT OF 1933, AS AMENDED,

December 21, 2018 EX-10.1

Purchase Agreement, dated December 20, 2018, by and among the Company and the Investors set forth on the signature pages thereto (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on December 21, 2018 (File No. 001-36351)).

Exhibit 10.1 PURCHASE AGREEMENT THIS PURCHASE AGREEMENT (“Agreement”) is made as of the 20th day of December, 2018 by and among PLx Pharma Inc., a Delaware corporation (the “Company”), and the Investors set forth on the signature pages affixed hereto (each an “Investor” and collectively the “Investors”). Recitals A. The Company and the Investors are executing and delivering this Agreement in relia

December 21, 2018 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 20, 2018 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File

December 21, 2018 EX-4.1

Form of Certificate of Designations, Preferences and Rights of Series A Convertible Preferred Stock.

Exhibit 4.1 CERTIFICATE OF DESIGNATIONS, PREFERENCES AND RIGHTS OF SERIES A CONVERTIBLE PREFERRED STOCK OF PLX PHARMA INC. (Pursuant to Section 151 of the Delaware General Corporation Law) PLx Pharma Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), hereby certifies that, pursuant to authority vested in the Board of Directors of the Company by Arti

November 9, 2018 10-Q

PLXP / PLx Pharma Inc. FORM 10-Q (Quarterly Report)

10-Q 1 plxp2018093010q.htm FORM 10-Q Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended September 30, 2018 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-363

November 9, 2018 EX-10.1

PLx Pharma Inc. 2018 Incentive Plan (incorporated by reference to Exhibit 10.1 to the Company’s Quarterly Report on Form 10-Q filed on November 9, 2018 (File No. 001-36351)).

Exhibit 10.1 PLx Pharma Inc. 2018 Incentive Plan Article 1 Establishment and Purpose 1.1 Establishment of the Plan. PLx Pharma Inc., a Delaware corporation (the “Company”), hereby establishes an incentive compensation plan (the “Plan”), as set forth in this document. 1.2 Purpose of the Plan. The purpose of the Plan is to promote the success and enhance the value of the Company by linking the perso

September 19, 2018 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): September 13, 2018 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File

August 31, 2018 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 29, 2018 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Nu

August 31, 2018 EX-10.1

Employment Agreement of Efthymios Deliargyris, dated as of August 29, 2018 (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on August 31, 2018 (File No. 001-36351)).

Exhibit 10.1 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (the “Agreement”) is made and entered into as of August 29, 2018, by and between Efthymios Deliargyris, MD, FACC, FESC, FSCAI (the “Executive”) and PLx Pharma Inc., a Delaware corporation (the “Company”). WHEREAS, the Company desires to employ the Executive on the terms and conditions set forth herein; and WHEREAS, the Executive desires t

August 10, 2018 DEF 14A

PLXP / PLx Pharma Inc. DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of The Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confide

August 10, 2018 10-Q

PLXP / PLx Pharma Inc. FORM 10-Q (Quarterly Report)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 30, 2018 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of registra

August 10, 2018 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 10, 2018

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 10, 2018 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Nu

August 10, 2018 8-K

PLx Pharma Inc. August 2018 Corporate Presentation.

August 6, 2018 EX-16.1

Letter of GBH CPAs, PC, dated August 6, 2018 (incorporated by reference to Exhibit 16.1 to the Company’s Current Report on Form 8-K filed on August 6, 2018 (File No. 001-36351)).

Exhibit 16.1 United States Securities and Exchange Commission Office of the Chief Accountant 100 F Street, N.E. Washington, D.C. 20549 Ladies and Gentleman: We have read the statements under Item 4.01 in the Form 8-K dated August 6, 2018, of PLx Pharma Inc. (the “Company’’) to be filed with the Securities and Exchange Commission and we agree with such statements therein as related to our firm. We

August 6, 2018 8-K

Financial Statements and Exhibits, Changes in Registrant's Certifying Accountant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): August 6, 2018 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

May 11, 2018 10-Q

PLXP / PLx Pharma Inc. FORM 10-Q (Quarterly Report)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended March 31, 2018 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of registr

April 27, 2018 10-K/A

PLXP / PLx Pharma Inc. FORM 10-K/A (Annual Report)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) ☒ Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2017 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

March 23, 2018 EX-21.1

Subsidiaries of the Company.*

Exhibit 21.1 Subsidiaries of PLx Pharma Inc. 1. PLx Opco Inc., organized under the laws of Delaware 2. PLx Chile SpA, organized under the laws of Chile 3. Dipexium Pharmaceuticals Ireland Limited, organized under the laws of Ireland

March 23, 2018 10-K

PLXP / PLx Pharma Inc. FORM 10-K (Annual Report)

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2017 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-36351 PLx phar

March 23, 2018 EX-99.1

PLx Pharma Inc. Reports Fourth Quarter and Full Year 2017 Results

Exhibit 99.1 For Immediate Release PLx Pharma Inc. Reports Fourth Quarter and Full Year 2017 Results Houston, Texas, March 23, 2018 — PLx Pharma Inc. (NASDAQ:PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company focused on commercializing two patent-protected products, Aspertec™ 325 mg and Aspertec™ 81 mg (referred to together as “Aspertec”™), announced today certain financ

March 23, 2018 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 23, 2018 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Num

January 8, 2018 8-K

DPRX / Dipexium Pharmaceuticals, Inc. EX 99.1 - CORPORATE PRESENTATION (Current Report)

Confidential Corporate Presentation Nasdaq: PLXP 2 Forward-Looking Statements This presenta,on includes or incorporates by reference statements that cons,tute forward-‐looking statements within the meaning of Sec,on 27A of the Securi,es Act of 1933, as amended, and Sec,on 21E of the Securi,es Act of 1934, as amended.

January 8, 2018 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): January 8, 2018 PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Nu

November 20, 2017 SC 13D

DPRX / Dipexium Pharmaceuticals, Inc. / Park West Asset Management LLC - PLXPHARMA INC. 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

November 9, 2017 10-Q

PLXP / PLx Pharma Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended September 30, 2017 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of registrant as specifi

October 27, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 26, 2017 PLx Pharma Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-36351 46-4995704 (State or Other Jurisdiction of Incorporation) (Commission File Numbe

September 28, 2017 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

plxp201709268k.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 September 28, 2017 Date of Report (Date of earliest event reported) PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or other jurisdiction of incorporation

September 28, 2017 EX-99.1

PLx Pharma Inc. September 2017 Corporate Presentation

Image Exhibit Exhibit 99.1

September 19, 2017 EX-10.1

Amendment to Amended and Restated Employment Agreement of Gary Mossman, effective as of September 15, 2017 (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on September 19, 2017 (File No. 001-36351)).

ex10-1.htm Exhibit 10.1 Amendment To AMENDED AND RESTATED EMPLOYMENT AGREEMENT This Amendment to Amended and Restated Employment Agreement (this ?Amendment?) is entered into between PLx Opco Inc., a Delaware corporation, formerly known as PLx Pharma Inc. (?Company?), and Gary Mossman (?Executive?) for the purpose of amending that one certain Amended and Restated Employment Agreement dated May 13,

September 19, 2017 EX-99.1

PLx Pharma Hires Key Commercial Executives in Preparation for Future Launch of Aspertec Industry Veterans Will Support Manufacturing and Trade Sales

ex99-1.htm Exhibit 99.1 PLx Pharma Hires Key Commercial Executives in Preparation for Future Launch of Aspertec Industry Veterans Will Support Manufacturing and Trade Sales HOUSTON, TX, September 19, 2017 — PLx Pharma Inc. (NASDAQ:PLXP) (“PLx” or the “Company”), a late-stage specialty pharmaceutical company focused on commercializing two patent-protected products, Aspertec™ 325 mg and Aspertec™ 81

September 19, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

8-K 1 plxp201709198k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 September 15, 2017 Date of Report (Date of earliest event reported) PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or other jurisdiction o

August 14, 2017 8-K/A

Financial Statements and Exhibits

plxp201708138ka.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 June 9, 2017 Date of Report (Date of earliest event reported) PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or other jurisdiction o

August 14, 2017 EX-10.1

AMENDED AND RESTATED PATENT LICENSE AGREEMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM PLX PHARMA INC. DATED DECEMBER 11, 2009 TABLE OF CONTENTS

ex10-1.htm Exhibit 10.1 AMENDED AND RESTATED PATENT LICENSE AGREEMENT BETWEEN THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM AND PLX PHARMA INC. DATED DECEMBER 11, 2009 TABLE OF CONTENTS 1. EFFECTIVE DATE 3 2. DEFINITIONS 4 3. WARRANTY: SUPERIOR RIGHTS 6 4. LICENSE 7 5. PAYMENTS AND REPORTS 9 6. COMMON STOCK: EQUITY OWNERSHIP AND PLX BOARD RIGHTS 12 7. TERM AND TERMINATION 12 8. INFRINGEME

August 14, 2017 EX-10.2

AMENDMENT NUMBER ONE TO AGREEMENT

ex10-2.htm Exhibit 10.2 AMENDMENT NUMBER ONE TO AGREEMENT This is the first amendment (“Amendment No. 1”) to the AMENDED AND RESTATED PATENT LICENSE AGREEMENT (the “License Agreement”), between The Board of Regents of The University of Texas System (“Board”) on behalf of The University of Texas Health Science Center at Houston (“UTHSC-H”) and PLx Pharma Inc., a Texas corporation with its principal

August 11, 2017 EX-3.3

Amended and Restated Certificate of Incorporation of PLx Pharma Inc. (incorporated by reference to Exhibit 3.3 to the Company’s Quarterly Report on Form 10-Q filed on August 11, 2017 (File No. 001-36351)).

Exhibit 3.3 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF PLX PHARMA INC. (reflecting Amendments filed April 18, 2017 and April 19, 2017) The undersigned, for the purposes of forming a corporation for conducting the business and promoting the purposes hereinafter stated, under the provisions and subject to the requirements of the laws of the State of Delaware (particularly Chapter 1, Title

August 11, 2017 10-Q

PLXP / PLx Pharma Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ Quarterly Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the Quarterly Period Ended June 30, 2017 Or ☐ Transition Report Under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number 001-36351 PLx Pharma Inc. (Exact name of registrant as specified in

August 10, 2017 EX-10.1

Loan and Security Agreement among PLx Pharma Inc., PLx Opco Inc., and Silicon Valley Bank, dated as of August 9, 2017 (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on August 10, 2017 (File No. 001-36351)).

ex10-1.htm Exhibit 10.1 LOAN AND SECURITY AGREEMENT THIS LOAN AND SECURITY AGREEMENT (this ?Agreement?) dated as of August 9, 2017 (the ?Effective Date?) between SILICON VALLEY BANK, a California corporation (?Bank?), and PLx Pharma Inc., a Delaware corporation and PLX OPCO INC., a Delaware corporation (each a ?Co-Borrower? and collectively ?Co-Borrowers?), provides the terms on which Bank shall l

August 10, 2017 8-K

Dipexium Pharmaceuticals FORM 8-K (Current Report/Significant Event)

plxp201707318k.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 August 9, 2017 Date of Report (Date of earliest event reported) PLx Pharma Inc. (Exact name of registrant as specified in its charter) Delaware 001-36351 46-4995704 (State or other jurisdiction of incorporation) (C

August 10, 2017 EX-4.1

Form of Warrant to Purchase Common Stock issued by PLx Pharma Inc. in connection with the Loan and Security Agreement among PLx Pharma Inc., PLx Opco Inc., and Silicon Valley Bank, dated as of August 9, 2017 (incorporated by reference to Exhibit 4.1 to the Company’s Current Report on Form 8-K filed on August 10, 2017 (File No. 001-36351)).

ex4-1.htm Exhibit 4.1 THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE ?ACT?), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR, IN THE OPINION OF LEGAL COUNSEL IN FORM A

June 22, 2017 SC 13G/A

PLXP / PLx Pharma Inc. / ZIMMERMAN RONALD - SCHEDULE 13G/A Passive Investment

zimmer20170622sc13ga.htm CUSIP: 25456J104 13G 1 of 5 SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1) PLx Pharma Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 25456J104 (CUSIP Number) June 14, 2017 (Date of Event Which Requires Filing of this Statement) Check the approp

June 19, 2017 SC 13G

DPRX / Dipexium Pharmaceuticals, Inc. / Park West Asset Management LLC - PLX PHARMA INC. 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* PLx Pharma Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 72942A107 (CUSIP Number) June 9, 2017 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant

June 12, 2017 EX-10.3

Amendment No. 2 to Amended and Restated Patent License Agreement, dated December 17, 2011 (incorporated by reference to Exhibit 10.3 to the Company’s Form 8-K filed on June 12, 2017 (File No. 001-36351)).

ex10-3.htm Exhibit 10.3 AMENDMENT NUMBER TWO TO AGREEMENT This is the second amendment (?Amendment No. 2?) to the AMENDED AND RESTATED PATENT LICENSE AGREEMENT (the ?License Agreement?), between The Board of Regents of The University of Texas System (?Board?) on behalf of The University of Texas Health Science Center at Houston (?UTHSC-H?) and PLx Pharma Inc., a Texas corporation with its principa

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