| Saham Diterbitkan | 26,832,457 shares |
| Saham Orang Dalam | 1,118,641 shares |
| Pemilikan Orang Dalam | 4.17 % |
| Jumlah Orang Dalam | 61 |
Skor Sentimen Orang Dalam
Skor Sentimen Orang Dalam mendapati syarikat dibeli oleh orang dalam korporat.
Ia adalah hasil daripada model kuantitatif berbilang faktor yang canggih yang mengenal pasti syarikat dengan tahap pengumpulan orang dalam yang paling tinggi. Model pemarkahan menggunakan gabungan bilangan bersih orang dalam yang membeli 90 hari sebelumnya, jumlah saham yang dibeli sebagai peratusan saham beredar, dan jumlah saham yang dimiliki oleh orang dalam. Nombor ini berjulat dari 0 hingga 100, dengan nombor yang lebih tinggi menunjukkan tahap pengumpulan yang lebih tinggi kepada rakannya, dan 50 adalah purata.
Kekerapan Kemas Kini: Harian
Skor Sentimen Pegawai
Skor Sentimen Pegawai mendapati syarikat dibeli oleh Pegawai Korporat.
Mengikut definisi Pegawai Korporat ialah Orang Dalam Korporat, tetapi tidak seperti beberapa Orang Dalam yang lain (10% Pemegang Saham dan Ahli Lembaga), Pegawai bekerja untuk syarikat tersebut setiap hari, dan mereka menggunakan wang mereka sendiri semasa berdagang . (10% Pemegang Saham dan Ahli Lembaga Pengarah selalunya pengurus dana yang menguruskan wang orang lain.) Oleh itu, dagangan orang dalam yang dibuat oleh Pegawai adalah lebih penting dan harus dilayan dengan sewajarnya.
Seperti Skor Sentimen Orang Dalam, Skor Sentimen Pegawai adalah hasil daripada model kuantitatif berbilang faktor yang canggih yang mengenal pasti syarikat yang mempunyai tahap pengumpulan pegawai tertinggi.
Kekerapan Kemas Kini: Harian
Metrik Orang Dalam Utama
Kad ini menunjukkan bagaimana kedudukan syarikat mengikut pelbagai metrik orang dalam. Kedudukan persentil menunjukkan cara syarikat ini dibandingkan dengan syarikat lain di pasaran AS. Kedudukan yang lebih tinggi menunjukkan keadaan yang lebih baik.
Sebagai contoh, adalah diterima umum bahawa pembelian orang dalam ialah penunjuk positif, jadi syarikat yang mempunyai lebih banyak pembelian orang dalam akan mendapat kedudukan lebih tinggi daripada syarikat yang kurang pembelian orang dalam (atau malah jualan orang dalam).
Peratusan Saham Beredar yang Dibeli oleh Orang Dalam (Kedudukan)
0.000 %( )
1259 out of 11244Peratusan Saham Beredar yang Dibeli oleh Orang Dalam ialah jumlah bilangan saham yang dibeli oleh orang dalam tolak jumlah bilangan saham yang dijual oleh orang dalam dalam tempoh 90 hari terakhir, dibahagikan dengan jumlah saham beredar dan didarab dengan 100.
Carta Dagangan Dalaman
Syros Pharmaceuticals, Inc. dagangan dalaman ditunjukkan dalam carta berikut. Orang dalam ialah pegawai, pengarah atau pelabur penting dalam syarikat. Secara umumnya adalah menyalahi undang-undang bagi orang dalam untuk membuat perdagangan dalam syarikat mereka berdasarkan maklumat material dan bukan awam. Ini tidak bermakna haram untuk mereka membuat sebarang perdagangan dalam syarikat mereka sendiri. Walau bagaimanapun, mereka mesti melaporkan semua dagangan kepada SEC melalui Borang 4.
Senarai Orang Dalam dan Metrik Keberuntungan
Jadual ini menunjukkan senarai orang dalam yang diketahui dan dijana secara automatik daripada pemfailan yang didedahkan kepada SEC. Sebagai tambahan kepada nama, gelaran terkini dan pengarah, pegawai, atau 10% jawatan pemilik, kami menyediakan pegangan yang didedahkan terkini. Selain itu, apabila boleh, kami menyediakan sejarah prestasi perdagangan untuk orang dalam. Sejarah prestasi perdagangan ialah purata wajaran prestasi transaksi pembelian pasaran terbuka sebenar yang dibuat oleh orang dalam. Untuk mendapatkan maklumat lanjut tentang cara ini dikira, tonton webinar YouTube ini.
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| Orang dalam | Purata Keuntungan (%) | Saham Dimiliki |
Berpecah Dilaraskan |
|---|---|---|---|
|
Noubar Afeyan
10% Owner -
|
0 | 0 | |
|
Aisling Capital Iii Lp
10% Owner -
|
908,565 | 90,856 | |
| Srinivas Akkaraju Director - [D] | 9,333 | 9,333 | |
|
ARCH Venture Partners VII, L.P.
10% Owner -
|
4,242,051 | 424,205 | |
|
ARCH Venture Partners VII, LLC
10% Owner -
|
4,242,051 | 424,205 | |
|
Aisling Capital Partners III LLC
10% Owner -
|
908,565 | 90,856 | |
|
Aisling Capital Partners III LP
10% Owner -
|
908,565 | 90,856 | |
| Mark J Alles Director - [D] | 3,666 | 3,666 | |
|
Arch Venture Fund VII LP
10% Owner -
|
4,242,051 | 424,205 | |
| Michael W Bonney | 11,000 | ||
|
Clinton Bybee
10% Owner -
|
4,242,051 | 424,205 | |
| Stephane Bancel Director - [D] | 47,980 | 4,798 | |
|
Keith Crandell
10% Owner -
|
4,242,051 | 424,205 | |
| Conley Chee President & CEO, Director - [D] [O] | 0 | 0 | |
|
Management Co Deerfield
10% Owner -
|
628,566 | 62,857 | |
| Colleen Elizabeth DeSimone Principal Accounting Officer - [O] | 0 | 0 | |
|
Deerfield Mgmt III, L.P.
10% Owner -
|
628,566 | 62,857 | |
|
Deerfield Mgmt L.P.
10% Owner -
|
628,566 | 62,857 | |
|
Deerfield Private Design Fund III, L.P.
10% Owner -
|
628,566 | 62,857 | |
|
Deerfield Special Situations Fund, L.P.
10% Owner -
|
628,566 | 62,857 |
| Orang dalam | Purata Keuntungan (%) | Saham Dimiliki |
Berpecah Dilaraskan |
|---|---|---|---|
| Deborah Dunsire Director - [D] | 12,000 | 12,000 | |
|
Steve Elms
10% Owner -
|
908,565 | 90,856 | |
| Sue Gail Eckhardt Director - [D] | 16,000 | 16,000 | |
| Marsha Fanucci Director - [D] | 16,000 | 16,000 | |
| Joseph J Jr Ferra Chief Financial Officer - [O] | 87,000 | 8,700 | |
|
Flagship VentureLabs IV, LLC
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV General Partner LLC
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV, L.P.
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV-Rx, L.P.
10% Owner -
|
0 | 0 | |
|
James E Flynn
10% Owner -
|
628,566 | 62,857 | |
|
Nathanael Gray
10% Owner -
|
853,332 | 85,333 | |
|
Jeremy Green
10% Owner -
|
49,793 | 4,979 | |
| Jason Haas Chief Financial Officer - [O] | 0 | 0 | |
|
JEB Syros Trust
10% Owner -
|
703,332 | 70,333 | |
|
Edwin M Jr Kania
10% Owner -
|
0 | 0 | |
| Kuvalanka Kyle D. | 78,000 | ||
|
Robert Nelsen
10% Owner -
|
4,242,051 | 424,205 | |
|
Amir Nashat
Director, 10% Owner -
[D]
|
48,320 | 4,832 | |
| Oh Andrew M. Director - [D] | 16,000 | 16,000 | |
| Eric R Olson Chief Scientific Officer - [O] | 6,661 | 6,661 |
| Orang dalam | Purata Keuntungan (%) | Saham Dimiliki |
Berpecah Dilaraskan |
|---|---|---|---|
| Sanj K Patel | 11,000 | ||
|
Perspecta Trust LLC
10% Owner -
|
703,332 | 70,333 | |
|
Polaris Entrepreneurs' Fund VII, L.P.
10% Owner -
|
48,320 | 4,832 | |
|
Polaris Management Co. VII, L.L.C.
10% Owner -
|
48,320 | 4,832 | |
|
Polaris Partners VII, L.P.
10% Owner -
|
48,320 | 4,832 | |
|
Dennis J Purcell
10% Owner -
|
908,565 | 90,856 | |
| Gerald E Quirk Chief Legal & Compliance Offic - [O] | 0 | 0 | |
|
Redmile Group, LLC
10% Owner -
|
49,793 | 4,979 | |
| David Roth Chief Medical Officer - [O] | 0 | 0 | |
| Vicki L Sato | 11,000 | ||
|
Andrew N Schiff
10% Owner -
|
908,565 | 90,856 | |
| Philip A Sharp Director - [D] | 40,000 | 4,000 | |
| Alice Tsang Shaw | 22,000 | ||
| Nancy A Simonian Director - [D] | 4,000 | 4,000 | |
| Springhorn Jeremy P. Chief Business Officer - [O] | 35,000 | 3,500 | |
| Kristin Stephens Chief Development Officer - [O] | 0 | 0 | |
| Timothy Tyson Director - [D] | 33,189 | 33,189 | |
| Peter Wirth Director - [D] | 16,000 | 16,000 | |
|
WuXi Healthcare Ventures II, L.P.
10% Owner -
|
423,805 | 42,380 | |
|
WuXi PharmTech Healthcare Fund I L.P.
10% Owner -
|
931,857 | 93,186 | |
| Richard A Young Director - [D] | 10,667 | 10,667 |
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Rekod Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek
Dalam bahagian ini, kami menganalisis keuntungan setiap pembelian orang dalam pasaran terbuka yang tidak dirancang yang dibuat dalam SYRS / Syros Pharmaceuticals, Inc.. Analisis ini membantu untuk memahami sama ada orang dalam secara konsisten menjana pulangan tidak normal dan patut diikuti. Analisis ini adalah untuk satu tahun selepas setiap perdagangan, dan hasilnya adalah bersifat teori .
Jadual berikut menunjukkan pembelian pasaran terbuka terkini yang bukan sebahagian daripada pelan dagangan automatik.
Harga Larasan ialah harga larasan berpecah. Saham Larasan ialah saham terlaras pecah.
Rekod Jejak Jualan Orang Dalam - Analisis Kerugian Jangka Pendek
Dalam bahagian ini, kami menganalisis pengelakan kerugian jangka pendek bagi setiap jualan dalaman pasaran terbuka yang tidak dirancang yang dibuat dalam SYRS / Syros Pharmaceuticals, Inc.. Corak pengelakan kerugian yang konsisten mungkin mencadangkan bahawa urus niaga jualan masa hadapan mungkin meramalkan penurunan harga. Analisis ini adalah untuk satu tahun selepas setiap perdagangan, dan hasilnya adalah bersifat teori .
Jadual berikut menunjukkan jualan pasaran terbuka terkini yang bukan sebahagian daripada pelan dagangan automatik.
Harga Larasan ialah harga larasan berpecah. Saham Larasan ialah saham terlaras pecah.
Sejarah Transaksi
Klik ikon pautan untuk melihat sejarah transaksi penuh. Transaksi yang dilaporkan sebagai sebahagian daripada pelan dagangan automatik 10b5-1 akan mempunyai X dalam lajur bertanda 10b-5.
| Fail Tarikh |
Dagangan Tarikh |
Borang | Orang dalam | Simbol Saham | Nama Sekuriti | Kod | Langsung | Harga Pelaksanaan |
Harga Unit |
Unit Berubah |
Nilai Berubah (1K) |
Baki Opsyen |
Baki Saham |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-12-04 | 2024-12-02 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 0.2702 | -37,070 | -10 | 4,000 | ||||
| 2024-11-27 | 2024-11-25 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 0.2653 | -134,713 | -36 | 41,070 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Haas Jason | SYRS | Common Stock | D | 0.2103 | -137,803 | -29 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Chee Conley | SYRS | Common Stock | D | 0.1998 | -134,797 | -27 | 0 | ||||
| 2024-11-20 | 2024-11-19 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 0.2212 | -46,657 | -10 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Stephens Kristin | SYRS | Common Stock | D | 0.2200 | -36,133 | -8 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Roth David | SYRS | Common Stock | D | 0.1969 | -12,099 | -2 | 0 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 40,125 | 175,783 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2.0900 | -8,707 | -18 | 130,797 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 17,000 | 139,504 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Roth David | SYRS | Common Stock | D | 2.0900 | -6,776 | -14 | 12,099 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Roth David | SYRS | Common Stock | D | 18,875 | 18,875 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2.0900 | -5,624 | -12 | 137,803 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 18,875 | 143,427 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2.0900 | -6,104 | -13 | 36,133 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 17,000 | 42,237 | ||||||
| 2024-10-02 | 2024-09-30 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 2.1000 | -3,100 | -7 | 46,657 | ||||
| 2024-10-02 | 2024-09-30 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 10,000 | 49,757 | ||||||
| 2024-09-18 | 2024-09-16 | 4 | Young Richard A | SYRS | Common Stock | D | 2,667 | 10,667 | ||||||
| 2024-09-18 | 2024-09-16 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 2,667 | 9,333 | ||||||
| 2024-09-12 | 2024-09-11 | 4 | Chee Conley | SYRS | Common Stock | D | 1.7084 | 50,000 | 85 | 122,504 | ||||
| 2024-09-12 | 2024-09-10 | 4 | Chee Conley | SYRS | Common Stock | D | 1.5052 | 50,000 | 75 | 72,504 | ||||
| 2024-09-12 | 2024-09-12 | 4 | Haas Jason | SYRS | Common Stock | D | 1.6762 | 45,344 | 76 | 124,552 | ||||
| 2024-09-12 | 2024-09-11 | 4 | Haas Jason | SYRS | Common Stock | D | 1.5781 | 19,293 | 30 | 79,208 | ||||
| 2024-09-12 | 2024-09-10 | 4 | Haas Jason | SYRS | Common Stock | D | 1.5493 | 35,363 | 55 | 59,915 | ||||
| 2024-07-02 | 2024-06-28 | 4 | Young Richard A | SYRS | Common Stock | D | 5.1200 | -34,837 | -178 | 8,000 | ||||
| 2024-06-07 | 2024-06-05 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 4,000 | 135,658 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | WIRTH PETER | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 4,000 | 33,189 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Young Richard A | SYRS | Common Stock | D | 4,000 | 42,837 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Dunsire Deborah | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 4,000 | 6,666 | ||||||
| 2024-04-05 | 2024-04-03 | 4 | Roth David | SYRS | Common Stock | D | 4.9500 | -10,451 | -52 | 0 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 5.1200 | -4,218 | -22 | 25,237 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 11,666 | 29,455 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2,000 | 17,789 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 5.1200 | -14,052 | -72 | 131,658 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 39,566 | 145,710 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 6,000 | 106,144 | ||||||
| 2024-04-02 | 2024-04-02 | 4 | Roth David | SYRS | Common Stock | D | 4.9803 | -150 | -1 | 10,451 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Roth David | SYRS | Common Stock | D | 5.1200 | -4,732 | -24 | 10,601 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Roth David | SYRS | Common Stock | D | 13,333 | 15,333 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Roth David | SYRS | Common Stock | D | 2,000 | 2,000 | ||||||
| 2024-04-02 | 2024-03-28 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 5.5900 | -7,046 | -39 | 39,757 | ||||
| 2024-04-02 | 2024-03-27 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 22,500 | 46,803 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Haas Jason | SYRS | Common Stock | D | 5.1200 | -4,732 | -24 | 24,552 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 13,333 | 29,284 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2,000 | 15,951 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Chee Conley | SYRS | Common Stock | D | 5.1200 | -3,500 | -18 | 22,504 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 11,666 | 26,004 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2,000 | 14,338 | ||||||
| 2023-12-26 | 2023-12-21 | 4 | AKKARAJU SRINIVAS By Samsara BioCapital, L.P. | SYRS | Common Stock | I | 4.4200 | 904,977 | 4,000 | 1,786,427 | ||||
| 2023-12-14 | 2023-12-12 | 4 | Roth David | SYRS | Common Stock | D | 4.9500 | -6,287 | -31 | 0 | ||||
| 2023-12-08 | 2023-12-06 | 4 | Roth David | SYRS | Common Stock | D | 3.9500 | -6,287 | -25 | 6,287 | ||||
| 2023-11-02 | 2023-11-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 2.2200 | -13,401 | -30 | 100,144 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 40,125 | 113,545 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Haas Jason | SYRS | Common Stock | D | 2.2200 | -6,301 | -14 | 13,951 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 18,875 | 20,252 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2.2200 | -5,676 | -13 | 15,789 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 17,000 | 21,465 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Roth David | SYRS | Common Stock | D | 2.2200 | -6,301 | -14 | 12,574 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Roth David | SYRS | Common Stock | D | 18,875 | 18,875 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Chee Conley | SYRS | Common Stock | D | 2.2200 | -6,004 | -13 | 12,338 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 17,000 | 18,342 | ||||||
| 2023-10-20 | 2023-10-19 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 2.1000 | -6,897 | -14 | 24,303 | ||||
| 2023-10-20 | 2023-10-11 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 22,500 | 31,200 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | Young Richard A | SYRS | Common Stock | D | 2,666 | 38,837 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 2,666 | 2,666 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | Alles Mark J | SYRS | Common Stock | D | 2,666 | 3,666 | ||||||
| 2023-08-02 | 2023-07-31 | 4 | Roth David | SYRS | Common Stock | D | 3.9500 | -7,348 | -29 | 0 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 3.5000 | -689 | -2 | 6,661 | ||||
| 2023-06-02 | 2023-06-01 | 4 | WIRTH PETER | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Young Richard A | SYRS | Common Stock | D | 4,000 | 36,171 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 4,000 | 29,189 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | TYSON TIMOTHY | SYRS | Common Stock | D | 257 | 8,257 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | TYSON TIMOTHY | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 691,489 | 881,450 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Chee Conley | SYRS | Common Stock | D | 2.5800 | -658 | -2 | 1,342 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2,000 | 2,000 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Olson Eric R | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 7,350 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Olson Eric R | SYRS | Common Stock | D | 2,000 | 7,973 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 4,465 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2,000 | 5,088 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 2.5800 | -1,852 | -5 | 73,420 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 6,000 | 75,272 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Haas Jason | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 1,377 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2,000 | 2,000 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Roth David | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 7,348 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Roth David | SYRS | Common Stock | D | 2,000 | 7,971 | ||||||
| 2022-10-13 | 3 | Quirk Gerald E | SYRS | Common Stock | D | 8,700 | ||||||||
| 2022-10-03 | 2022-09-30 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 6.3704 | 14,000 | 89 | 24,932 | ||||
| 2022-10-03 | 2022-09-29 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 5.7196 | 2,932 | 17 | 10,932 | ||||
| 2022-09-19 | 2022-09-16 | 4 | WIRTH PETER | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Dunsire Deborah | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-04-04 | 2022-04-01 | 4 | Roth David | SYRS | Common Stock | D | 1.1200 | -27,281 | -31 | 59,719 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 1.1200 | -14,115 | -16 | 30,885 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 1.1200 | -58,883 | -66 | 692,723 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.1200 | -27,266 | -31 | 59,734 | ||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Restricted Stock Units | D | 400,000 | 400,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Restricted Stock Units | D | 240,000 | 240,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1.59 | 375,000 | 375,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Restricted Stock Units | D | 200,000 | 200,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 1.59 | 125,000 | 125,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Restricted Stock Units | D | 200,000 | 200,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.59 | 100,000 | 100,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Restricted Stock Units | D | 200,000 | 200,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Stock Option (right to buy) | D | 1.59 | 100,000 | 100,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Haas Jason | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Haas Jason | SYRS | Stock Option (right to buy) | D | 1.59 | 125,000 | 125,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Chee Conley | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Chee Conley | SYRS | Stock Option (right to buy) | D | 1.59 | 100,000 | 100,000 | |||||
| 2022-01-06 | 2022-01-05 | 4 | Olson Eric R | SYRS | Common Stock | D | 3.4669 | -2,208 | -8 | 0 | ||||
| 2021-10-13 | 2021-10-12 | 4 | Haas Jason | SYRS | Stock Option (right to buy) | D | 4.54 | 750,000 | 750,000 | |||||
| 2021-09-28 | 2021-09-27 | 4 | Chee Conley | SYRS | Stock Option (right to buy) | D | 4.81 | 360,000 | 360,000 | |||||
| 2021-09-10 | 2021-09-09 | 4 | Dunsire Deborah | SYRS | Stock Option (right to buy) | D | 5.28 | 35,000 | 35,000 | |||||
| 2021-07-01 | 2021-07-01 | 4 | Olson Eric R | SYRS | Common Stock | D | 5.5500 | -1,164 | -6 | 0 | ||||
| 2021-06-10 | 2021-06-08 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Eckhardt Sue Gail | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 3 | Stephens Kristin | SYRS | Common Stock | D | 45,000 | ||||||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | -3,628 | 90,697 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Common Stock | D | 9.4740 | -3,628 | -34 | 0 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 3,628 | 4 | 3,628 | ||||
| 2021-02-19 | 2021-02-17 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11.41 | 94,000 | 94,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 11.41 | 94,000 | 94,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 11.41 | 94,000 | 94,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 11.41 | 119,000 | 119,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 11.41 | 119,000 | 119,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 11.41 | 304,000 | 304,000 | |||||
| 2021-02-18 | 2021-02-16 | 4 | Young Richard A | SYRS | Common Stock | D | 12.0500 | -3,750 | -45 | 321,711 | ||||
| 2021-02-10 | 2020-11-17 | 4/A | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,357 | -47 | 329,211 | ||||
| 2021-02-10 | 2020-11-16 | 4/A | Young Richard A | SYRS | Common Stock | D | 8.9800 | -633 | -6 | 334,568 | ||||
| 2021-02-10 | 2021-02-08 | 4 | Young Richard A | SYRS | Common Stock | D | 13.0400 | -3,750 | -49 | 325,461 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10.09 | -4,988 | 280,012 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 8.51 | -14,168 | 79,165 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -10,761 | 21,524 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 10.0900 | 4,988 | 50 | 563,606 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 8.5100 | 14,168 | 121 | 558,618 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3.0400 | 10,761 | 33 | 544,450 | ||||
| 2020-12-11 | 2020-12-08 | 4 | AKKARAJU SRINIVAS | SYRS | Warrants (right to buy) | I | 11.00 | 156,250 | 156,250 | |||||
| 2020-12-11 | 2020-12-08 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 625,000 | 1,899,616 | ||||||
| 2020-11-18 | 2020-11-17 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,357 | -47 | 339,211 | ||||
| 2020-11-18 | 2020-11-16 | 4 | Young Richard A | SYRS | Common Stock | D | 8.9800 | -633 | -6 | 344,568 | ||||
| 2020-10-19 | 2020-10-19 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,673 | -50 | 335,201 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -317 | -3 | 340,874 | ||||
| 2020-09-16 | 2020-09-15 | 4 | Young Richard A | SYRS | Common Stock | D | 10.3900 | -5,990 | -62 | 341,191 | ||||
| 2020-09-09 | 2020-09-08 | 4 | Eckhardt Sue Gail | SYRS | Stock Option (right to buy) | D | 8.94 | 35,000 | 35,000 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Young Richard A | SYRS | Common Stock | D | 12.5900 | -5,990 | -75 | 347,181 | ||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | -10,787 | 94,325 | |||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 13.0000 | -10,787 | -140 | 0 | ||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 10,787 | 11 | 10,787 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | -4,963 | 105,112 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 13.0000 | -4,963 | -65 | 0 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 4,963 | 5 | 4,963 | ||||
| 2020-08-19 | 2020-08-18 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 13.0955 | -158,583 | -2,077 | 1,274,616 | ||||
| 2020-08-19 | 2020-08-17 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 13.0000 | -744 | -10 | 1,433,199 | ||||
| 2020-07-17 | 2020-07-15 | 4 | Young Richard A | SYRS | Common Stock | D | 11.8500 | -5,990 | -71 | 353,171 | ||||
| 2020-07-07 | 2020-07-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 11.7162 | -1,753 | -21 | 0 | ||||
| 2020-07-06 | 2020-07-01 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.0149 | -4,627 | -51 | 1,433,943 | ||||
| 2020-06-25 | 2020-06-25 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.1484 | -54,972 | -613 | 1,438,570 | ||||
| 2020-06-25 | 2020-06-24 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.0669 | -48,775 | -540 | 1,493,542 | ||||
| 2020-06-25 | 2020-06-23 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.1069 | -50,953 | -566 | 1,542,317 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,990 | -52 | 359,161 | ||||
| 2020-06-11 | 2020-06-11 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-05-15 | 2020-05-15 | 4 | Young Richard A | SYRS | Common Stock | D | 9.2224 | -5,990 | -55 | 365,151 | ||||
| 2020-05-13 | 2020-05-13 | 4 | Alles Mark J | SYRS | Common Stock | D | 8.8590 | 10,000 | 89 | 10,000 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -23,960 | -210 | 371,141 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 7.3818 | -1,446 | -11 | 0 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 7.54 | 294,000 | 294,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -8,210 | 1,018,123 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -10,762 | 1,026,333 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -33,429 | 1,037,095 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3.0400 | 52,401 | 159 | 533,689 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 6.22 | 35,000 | 35,000 | |||||
| 2019-11-12 | 2019-11-12 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 4.9667 | 10,121 | 50 | 35,000 | ||||
| 2019-11-12 | 2019-11-11 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 4.9932 | 9,879 | 49 | 24,879 | ||||
| 2019-08-19 | 2019-08-16 | 4 | Young Richard A | SYRS | Common Stock | D | 10.0000 | -22,700 | -227 | 395,101 | ||||
| 2019-08-19 | 2019-08-15 | 4 | Young Richard A | SYRS | Common Stock | D | 10.0000 | -2,300 | -23 | 417,801 | ||||
| 2019-07-17 | 2019-07-17 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.6964 | -34,521 | -266 | 4,242,051 | ||||
| 2019-07-17 | 2019-07-16 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.8078 | -25,779 | -201 | 4,276,572 | ||||
| 2019-07-17 | 2019-07-15 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8.2651 | -2,700 | -22 | 4,302,051 | ||||
| 2019-06-12 | 2019-06-11 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Shaw Alice Tsang | SYRS | Stock Option (right to buy) | D | 5.60 | 22,000 | 22,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | BONNEY MICHAEL W | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Fanucci Marsha | SYRS | Common Stock (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | SATO VICKI L | SYRS | Common Stock (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-04-11 | 2019-04-09 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock Warrants (rights to buy) | I | 8.62 | 133,333 | 133,333 | |||||
| 2019-04-11 | 2019-04-09 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 7.5000 | 533,332 | 4,000 | 1,593,270 | ||||
| 2019-03-14 | 2019-03-14 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8.1498 | -43,000 | -350 | 4,305,051 | ||||
| 2019-03-14 | 2019-03-13 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8.1993 | -2,820 | -23 | 4,348,051 | ||||
| 2019-03-14 | 2019-03-13 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.8862 | -81,591 | -643 | 4,350,871 | ||||
| 2019-03-14 | 2019-03-12 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.3674 | -40,092 | -295 | 4,432,462 | ||||
| 2019-03-11 | 2019-03-11 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6.4924 | -44,878 | -291 | 4,472,554 | ||||
| 2019-03-11 | 2019-03-08 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6.9266 | -84,496 | -585 | 4,517,432 | ||||
| 2019-03-11 | 2019-03-07 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6.8736 | -35,209 | -242 | 4,601,928 | ||||
| 2019-02-14 | 2019-02-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Ferra Joseph J Jr | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Olson Eric R | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Roth David | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 6.71 | 285,000 | 285,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 188,000 | 669,288 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 87,000 | 102,000 | ||||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | 12,084 | 785,523 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1.01 | 75,050 | 797,607 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1.01 | 23,454 | 872,657 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3.0400 | 12,084 | 37 | 481,288 | ||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 1.0100 | 98,504 | 99 | 469,204 | ||||
| 2018-06-15 | 2018-06-14 | 4 | BONNEY MICHAEL W | SYRS | Stock Option (right to buy) | D | 12.95 | 13,000 | 13,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-03-12 | 2018-03-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 12.32 | 50,000 | 50,000 | |||||
| 2018-03-12 | 2018-03-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 12.32 | 150,000 | 150,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 10.09 | 75,000 | 75,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 13.30 | 11,666 | 11,666 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 10.09 | 75,000 | 75,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10.09 | 285,000 | 285,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 10.09 | 75,000 | 75,000 | |||||
| 2018-02-13 | 2017-09-08 | 5 | AFEYAN NOUBAR | SYRS | Common Stock | D | -24,527 | 0 | ||||||
| 2018-02-02 | 2018-01-31 | 4 | AKKARAJU SRINIVAS see footnote 1 | SYRS | Common Stock | I | 9.5500 | 209,424 | 2,000 | 1,059,938 | ||||
| 2017-12-22 | 3/A | AKKARAJU SRINIVAS By Samsara BioCapital, L.P. | SYRS | Common Stock | I | 740,740 | ||||||||
| 2017-12-15 | 2017-12-15 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 9.0840 | 15,000 | 136 | 15,000 | ||||
| 2017-12-14 | 2017-12-14 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 8.9900 | 26,600 | 239 | 830,494 | ||||
| 2017-12-14 | 2017-12-13 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 8.9700 | 68,400 | 614 | 803,894 | ||||
| 2017-12-14 | 2017-12-12 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 9.4000 | 14,774 | 139 | 735,494 | ||||
| 2017-11-14 | 2017-11-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11.65 | 50,000 | 50,000 | |||||
| 2017-11-14 | 2017-11-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11.65 | 150,000 | 150,000 | |||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Stock Option (right to buy) | D | 3.04 | -550 | 13,016 | |||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Common Stock | D | 16.0605 | -550 | -9 | 0 | ||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Common Stock | D | 3.0400 | 550 | 2 | 550 | ||||
| 2017-09-22 | 2017-06-08 | 4/A | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 14.62 | 22,000 | 22,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Nashat Amir | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Young Richard A | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | -54,293 | 0 | ||||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | -306,222 | 612,442 | ||||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | D | -1,295,997 | 2,378,663 | ||||||
| 2017-08-16 | 2017-08-14 | 4 | Young Richard A | SYRS | Common Stock | D | 22.0000 | -3,282 | -72 | 420,101 | ||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | 2,500 | 110,075 | |||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 23.5876 | -2,500 | -59 | 0 | ||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 2,500 | 3 | 2,500 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Young Richard A | SYRS | Common Stock | D | 22.0889 | -3,282 | -72 | 423,383 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | 12,500 | 25,025 | |||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Common Stock | D | 21.8500 | -12,500 | -273 | 0 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 12,500 | 13 | 12,500 | ||||
| 2017-06-12 | 3 | AKKARAJU SRINIVAS by Samsara BioCapital, L.P. | SYRS | Common Stock | I | 1,441,440 | ||||||||
| 2017-06-12 | 3 | AKKARAJU SRINIVAS by Samsara BioCapital, L.P. | SYRS | Common Stock | I | 1,441,440 | ||||||||
| 2017-06-12 | 2017-06-08 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 14.26 | 22,000 | 22,000 | |||||
| 2017-02-13 | 2017-02-09 | 5 | Young Richard A | SYRS | Common Stock | D | -106,667 | 426,665 | ||||||
| 2017-02-13 | 2017-02-10 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 10.90 | 63,500 | 63,500 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 10.90 | 40,000 | 40,000 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 10.90 | 63,500 | 63,500 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10.90 | 175,000 | 175,000 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Kuvalanka Kyle D. | SYRS | Stock Option (right to buy) | D | 10.90 | 78,000 | 78,000 | |||||
| 2017-01-30 | 2017-01-27 | 4 | WIRTH PETER | SYRS | Stock Option (Right to Buy) | D | 10.76 | 22,000 | 22,000 | |||||
| 2016-09-29 | 2016-09-27 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 13.30 | 105,000 | 105,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Bancel Stephane | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-16 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 12.17 | 75,000 | 75,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series B Preferred Stock | D | -1,589,269 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-3 Preferred Stock | D | -7,500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-2 Preferred Stock | D | -5,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-1 Preferred Stock | D | -1,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 12.5000 | 400,000 | 5,000 | 4,637,137 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 423,805 | 4,237,137 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 2,000,000 | 3,813,332 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 1,333,333 | 1,813,332 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 266,666 | 479,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Series B Preferred Stock | I | -83,129 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Series B Preferred Stock | I | -4,366,825 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 12.5000 | 26,153 | 327 | 48,320 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 12.5000 | 373,847 | 4,673 | 1,538,333 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 22,167 | 22,167 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 1,164,486 | 1,164,486 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series B Preferred Stock | I | -444,995 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series B Preferred Stock | I | -1,779,981 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-3 Preferred Stock | I | -1,500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-3 Preferred Stock | I | -6,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-2 Preferred Stock | I | -1,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-2 Preferred Stock | I | -4,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-1 Preferred Stock | I | -200,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-1 Preferred Stock | I | -800,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 12.5000 | 80,000 | 1,000 | 918,664 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 12.5000 | 320,000 | 4,000 | 3,674,660 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 118,665 | 838,664 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 474,661 | 3,354,660 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 400,000 | 719,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 1,600,000 | 2,879,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 266,666 | 319,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 1,066,666 | 1,279,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 53,333 | 53,333 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 213,333 | 213,333 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -151,576 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -117,931 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -982,762 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -178,074 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -317,853 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 9,373 | 117 | 49,793 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 174,320 | 2,179 | 205,767 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 104,670 | 1,308 | 366,739 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 144,383 | 1,805 | 191,869 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 40,420 | 40,420 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 31,447 | 31,447 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 262,069 | 262,069 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 47,486 | 47,486 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 84,760 | 84,760 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series B Preferred Stock | D | -1,994,471 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-3 Preferred Stock | D | -500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-1 Preferred Stock | D | -500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-2 Preferred Stock | D | -500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 531,858 | 931,857 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133,333 | 399,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133,333 | 399,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133,333 | 399,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Series B Preferred Stock | I | -83,129 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Series B Preferred Stock | I | -4,366,825 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 12.5000 | 26,153 | 327 | 48,320 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 12.5000 | 373,847 | 4,673 | 1,538,333 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 22,167 | 22,167 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 1,164,486 | 1,164,486 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Series B Preferred Stock | D | -1,907,122 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Common Stock | D | 12.5000 | 400,000 | 5,000 | 908,565 | ||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Common Stock | D | 508,565 | 508,565 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series B Preferred Stock | I | -1,589,269 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-3 Preferred Stock | I | -7,500,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-2 Preferred Stock | I | -5,000,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-1 Preferred Stock | I | -1,000,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 12.5000 | 400,000 | 5,000 | 4,637,137 | ||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 423,805 | 4,237,137 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 2,000,000 | 3,813,332 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 1,333,333 | 1,813,332 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 266,666 | 479,999 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Simonian Nancy A | SYRS | Series A-2 Preferred Stock | D | -250,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 66,666 | 370,702 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | D | -550,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40,000 | 40,000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40,000 | 40,000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40,000 | 40,000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | D | 146,666 | 146,666 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Bancel Stephane | SYRS | Series A-2 Preferred Stock | D | -100,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Bancel Stephane | SYRS | Common Stock | D | 26,666 | 47,980 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Series B Convertible Preferred Stock | I | -508,566 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Series B Convertible Preferred Stock | I | -1,186,654 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Common Stock | I | 12.5000 | 120,000 | 1,500 | 628,566 | ||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Common Stock | I | 12.5000 | 280,000 | 3,500 | 1,466,654 | ||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Common Stock | I | 508,566 | 508,566 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Common Stock | I | 1,186,654 | 1,186,654 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | WuXi Healthcare Ventures II, L.P. | SYRS | Series B Preferred Stock | D | -1,589,269 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | WuXi Healthcare Ventures II, L.P. | SYRS | Common Stock | D | 423,805 | 423,805 | ||||||
| 2016-06-29 | 3 | Gray Nathanael | SYRS | Common Stock | D | 853,332 | ||||||||
| 2016-06-29 | 3 | Gray Nathanael | SYRS | Common Stock | D | 853,332 | ||||||||
| 2016-06-29 | 3 | JEB Syros Trust | SYRS | Common Stock | D | 703,332 | ||||||||
| 2016-06-29 | 3 | JEB Syros Trust | SYRS | Common Stock | D | 703,332 | ||||||||
| 2016-06-29 | 3 | Bancel Stephane | SYRS | Common Stock | D | 42,628 | ||||||||
| 2016-06-29 | 3 | Bancel Stephane | SYRS | Common Stock | D | 42,628 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A | SYRS | Common Stock | D | 768,072 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o William H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o Bennett H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o William H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o Bennett H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A | SYRS | Common Stock | D | 768,072 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | NELSEN ROBERT Shares held by ARCH Venture Fund VII, L.P. | SYRS | Common Stock | I | 426,666 | ||||||||
| 2016-06-29 | 3 | NELSEN ROBERT Shares held by ARCH Venture Fund VII, L.P. | SYRS | Common Stock | I | 426,666 | ||||||||
| 2016-06-29 | 3 | Perspecta Trust LLC Owned by the JEB Syros Trust, of which Perspecta Trust LLC is trustee. | SYRS | Common Stock | I | 703,332 | ||||||||
| 2016-06-29 | 3 | Perspecta Trust LLC Owned by the JEB Syros Trust, of which Perspecta Trust LLC is trustee. | SYRS | Common Stock | I | 703,332 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | Young Richard A | SYRS | Common Stock | D | 1,066,664 | ||||||||
| 2016-06-29 | 3 | Young Richard A | SYRS | Common Stock | D | 1,066,664 |
P
Pasaran terbuka atau pembelian persendirian sekuriti bukan derivatif atau derivatif
S
Pasaran terbuka atau jualan persendirian sekuriti bukan derivatif atau derivatif
A
Pemberian, penganugerahan atau pemerolehan lain sekuriti daripada syarikat (seperti opsyen)
C
Penukaran derivatif
D
Penjualan atau pemindahan sekuriti kembali kepada syarikat
F
Pembayaran harga pelaksanaan atau liabiliti cukai menggunakan sebahagian daripada sekuriti yang diterima daripada syarikat
G
Hadiah sekuriti oleh atau kepada orang dalam
K
Swap ekuiti dan urus niaga lindung nilai yang serupa
M
Pelaksanaan atau penukaran sekuriti derivatif yang diterima daripada syarikat (seperti opsyen)
V
Transaksi dilaporkan secara sukarela pada Borang 4
J
Lain-lain (disertai dengan nota kaki yang menerangkan transaksi)
