| Saham Diterbitkan | 126,289,910 shares |
| Saham Orang Dalam | 38,975,141 shares |
| Pemilikan Orang Dalam | 30.86 % |
| Jumlah Orang Dalam | 38 |
Skor Sentimen Orang Dalam
Skor Sentimen Orang Dalam mendapati syarikat dibeli oleh orang dalam korporat.
Ia adalah hasil daripada model kuantitatif berbilang faktor yang canggih yang mengenal pasti syarikat dengan tahap pengumpulan orang dalam yang paling tinggi. Model pemarkahan menggunakan gabungan bilangan bersih orang dalam yang membeli 90 hari sebelumnya, jumlah saham yang dibeli sebagai peratusan saham beredar, dan jumlah saham yang dimiliki oleh orang dalam. Nombor ini berjulat dari 0 hingga 100, dengan nombor yang lebih tinggi menunjukkan tahap pengumpulan yang lebih tinggi kepada rakannya, dan 50 adalah purata.
Kekerapan Kemas Kini: Harian
Skor Sentimen Pegawai
Skor Sentimen Pegawai mendapati syarikat dibeli oleh Pegawai Korporat.
Mengikut definisi Pegawai Korporat ialah Orang Dalam Korporat, tetapi tidak seperti beberapa Orang Dalam yang lain (10% Pemegang Saham dan Ahli Lembaga), Pegawai bekerja untuk syarikat tersebut setiap hari, dan mereka menggunakan wang mereka sendiri semasa berdagang . (10% Pemegang Saham dan Ahli Lembaga Pengarah selalunya pengurus dana yang menguruskan wang orang lain.) Oleh itu, dagangan orang dalam yang dibuat oleh Pegawai adalah lebih penting dan harus dilayan dengan sewajarnya.
Seperti Skor Sentimen Orang Dalam, Skor Sentimen Pegawai adalah hasil daripada model kuantitatif berbilang faktor yang canggih yang mengenal pasti syarikat yang mempunyai tahap pengumpulan pegawai tertinggi.
Kekerapan Kemas Kini: Harian
Metrik Orang Dalam Utama
Kad ini menunjukkan bagaimana kedudukan syarikat mengikut pelbagai metrik orang dalam. Kedudukan persentil menunjukkan cara syarikat ini dibandingkan dengan syarikat lain di pasaran AS. Kedudukan yang lebih tinggi menunjukkan keadaan yang lebih baik.
Sebagai contoh, adalah diterima umum bahawa pembelian orang dalam ialah penunjuk positif, jadi syarikat yang mempunyai lebih banyak pembelian orang dalam akan mendapat kedudukan lebih tinggi daripada syarikat yang kurang pembelian orang dalam (atau malah jualan orang dalam).
Peratusan Saham Beredar yang Dibeli oleh Orang Dalam (Kedudukan)
-0.510 %( )
10950 out of 11224Peratusan Saham Beredar yang Dibeli oleh Orang Dalam ialah jumlah bilangan saham yang dibeli oleh orang dalam tolak jumlah bilangan saham yang dijual oleh orang dalam dalam tempoh 90 hari terakhir, dibahagikan dengan jumlah saham beredar dan didarab dengan 100.
Carta Dagangan Dalaman
Apellis Pharmaceuticals, Inc. dagangan dalaman ditunjukkan dalam carta berikut. Orang dalam ialah pegawai, pengarah atau pelabur penting dalam syarikat. Secara umumnya adalah menyalahi undang-undang bagi orang dalam untuk membuat perdagangan dalam syarikat mereka berdasarkan maklumat material dan bukan awam. Ini tidak bermakna haram untuk mereka membuat sebarang perdagangan dalam syarikat mereka sendiri. Walau bagaimanapun, mereka mesti melaporkan semua dagangan kepada SEC melalui Borang 4.
Senarai Orang Dalam dan Metrik Keberuntungan
Jadual ini menunjukkan senarai orang dalam yang diketahui dan dijana secara automatik daripada pemfailan yang didedahkan kepada SEC. Sebagai tambahan kepada nama, gelaran terkini dan pengarah, pegawai, atau 10% jawatan pemilik, kami menyediakan pegangan yang didedahkan terkini. Selain itu, apabila boleh, kami menyediakan sejarah prestasi perdagangan untuk orang dalam. Sejarah prestasi perdagangan ialah purata wajaran prestasi transaksi pembelian pasaran terbuka sebenar yang dibuat oleh orang dalam. Untuk mendapatkan maklumat lanjut tentang cara ini dikira, tonton webinar YouTube ini.
See our leaderboard of most profitable insider traders.
| Orang dalam | Purata Keuntungan (%) | Saham Dimiliki |
Berpecah Dilaraskan |
|---|---|---|---|
|
AJU IB Investment Co., Ltd.
10% Owner -
|
2,292,062 | 2,292,062 | |
| Steven Axon Chief Business Officer - [O] | 50,110 | 50,110 | |
| Caroline Baumal Chief Medical Officer - [O] | 93,301 | 93,301 | |
| Kelley Boucher Chief People Officer - [O] | 97,658 | 97,658 | |
| Brown Victoria L. Program Team Lead - [O] | 23,556 | 23,556 | |
| Lucia Celona See Remarks - [O] | 5,213 | 5,213 | |
| Gerald Chan Director - [D] | 17,705 | 17,705 | |
|
Bihua Chen
Director, 10% Owner -
[D]
|
3,473,925 | 3,473,925 | |
| James George Chopas VP/Chief Accounting Officer - [O] | 53,657 | 53,657 | |
|
Cormorant Asset Management, LLC
10% Owner -
|
3,473,925 | 3,473,925 | |
|
Cormorant Global Healthcare GP, LLC
10% Owner -
|
3,473,925 | 3,473,925 | |
|
Cormorant Global Healthcare Master Fund, LP
10% Owner -
|
3,473,925 | 3,473,925 |
| Orang dalam | Purata Keuntungan (%) | Saham Dimiliki |
Berpecah Dilaraskan |
|---|---|---|---|
| Mark Jeffrey DeLong Chief Business & Strat Officer - [O] | 83,945 | 83,945 | |
| Pascal Deschatelets Chief Scientific Officer - [O] | 1,160,496 | 1,160,496 | |
| Dunlop A. Sinclair Director - [D] | 158,393 | 158,393 | |
| Jeffrey Eisele Chief Development Officer - [O] | 55,312 | 55,312 | |
| Fonteyne Paul R. Director - [D] | 22,705 | 22,705 | |
| Cedric Francois Chief Executive Officer, Director - [D] [O] | 1,646,027 | 1,646,027 | |
|
Michael E Gellert
10% Owner -
|
943,989 | 943,989 | |
| Federico Grossi Chief Medical Officer - [O] | 94,884 | 94,884 | |
|
Hillhouse Capital Management, Ltd.
10% Owner -
|
3,527,152 | 3,527,152 | |
| Lackner Thomas A. See Remarks - [O] | 7,725 | 7,725 | |
| Karen Lewis Chief People Officer - [O] | 70,251 | 70,251 | |
| Leslie Meltzer Chief Research and Development - [O] | 61,804 | 61,804 | |
| Alec Machiels Director - [D] | 377,028 | 377,028 |
| Orang dalam | Purata Keuntungan (%) | Saham Dimiliki |
Berpecah Dilaraskan |
|---|---|---|---|
|
Morningside Venture Investments Ltd
10% Owner -
|
12,806,342 | 12,806,342 | |
| Nur Nicholson Chief Technical Officer - [O] | 83,664 | 83,664 | |
| Stephanie Monaghan O'Brien Director - [D] | 17,705 | 17,705 | |
| Nicole D Perry Vice President - Accounting - [O] | 4,847 | 4,847 | |
|
Potentia Holdings, LLC
10% Owner -
|
7,653,202 | 7,653,202 | |
| Lukas Scheibler Chief Research Officer - [O] | 68,299 | 68,299 | |
| Ahmad Sadr See Remarks - [O] | 2,725 | 2,725 | |
| Timothy Eugene Sullivan Chief Financial Officer - [O] | 128,665 | 128,665 | |
| Townsend Adam J. Chief Commercial Officer - [O] | 84,050 | 84,050 | |
| Craig A Wheeler Director - [D] | 16,483 | 16,483 | |
| Keli Walbert Director - [D] | 9,090 | 9,090 | |
| Watson David O. General Counsel - [O] | 203,866 | 203,866 | |
|
venBio Global Strategic Fund II L.P.
10% Owner -
|
3,579,305 | 3,579,305 |
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Rekod Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek
Dalam bahagian ini, kami menganalisis keuntungan setiap pembelian orang dalam pasaran terbuka yang tidak dirancang yang dibuat dalam APLS / Apellis Pharmaceuticals, Inc.. Analisis ini membantu untuk memahami sama ada orang dalam secara konsisten menjana pulangan tidak normal dan patut diikuti. Analisis ini adalah untuk satu tahun selepas setiap perdagangan, dan hasilnya adalah bersifat teori .
Jadual berikut menunjukkan pembelian pasaran terbuka terkini yang bukan sebahagian daripada pelan dagangan automatik.
Harga Larasan ialah harga larasan berpecah. Saham Larasan ialah saham terlaras pecah.
Rekod Jejak Jualan Orang Dalam - Analisis Kerugian Jangka Pendek
Dalam bahagian ini, kami menganalisis pengelakan kerugian jangka pendek bagi setiap jualan dalaman pasaran terbuka yang tidak dirancang yang dibuat dalam APLS / Apellis Pharmaceuticals, Inc.. Corak pengelakan kerugian yang konsisten mungkin mencadangkan bahawa urus niaga jualan masa hadapan mungkin meramalkan penurunan harga. Analisis ini adalah untuk satu tahun selepas setiap perdagangan, dan hasilnya adalah bersifat teori .
Jadual berikut menunjukkan jualan pasaran terbuka terkini yang bukan sebahagian daripada pelan dagangan automatik.
Harga Larasan ialah harga larasan berpecah. Saham Larasan ialah saham terlaras pecah.
Sejarah Transaksi
Klik ikon pautan untuk melihat sejarah transaksi penuh. Transaksi yang dilaporkan sebagai sebahagian daripada pelan dagangan automatik 10b5-1 akan mempunyai X dalam lajur bertanda 10b-5.
| Fail Tarikh |
Dagangan Tarikh |
Borang | Orang dalam | Simbol Saham | Nama Sekuriti | Kod | Langsung | Harga Pelaksanaan |
Harga Unit |
Unit Berubah |
Nilai Berubah (1K) |
Baki Opsyen |
Baki Saham |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-09-03 | 2025-09-02 | 4 | Chopas James George | APLS | Common Stock | D | 28.0770 | -548 | -15 | 53,657 | ||||
| 2025-09-03 | 2025-09-02 | 4 | Boucher Kelley | APLS | Common Stock | D | 30,476 | 97,658 | ||||||
| 2025-09-02 | 2025-08-26 | 4 | MELTZER LESLIE | APLS | Common Stock | D | 61,804 | 61,804 | ||||||
| 2025-08-29 | 2025-08-28 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 28.3900 | -49,963 | -1,418 | 307,946 | ||||
| 2025-08-29 | 2025-08-27 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 28.1900 | -175,037 | -4,934 | 357,909 | ||||
| 2025-08-19 | 2025-08-18 | 4 | Watson David O. | APLS | Common Stock | D | 27.8000 | -5,000 | -139 | 123,730 | ||||
| 2025-07-18 | 2025-07-17 | 4 | Francois Cedric | APLS | Common Stock | D | 20.2147 | -19,725 | -399 | 331,605 | ||||
| 2025-07-18 | 2025-07-17 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 8,997 | 39 | 351,330 | ||||
| 2025-07-18 | 2025-07-16 | 4 | Watson David O. | APLS | Common Stock | D | 19.5500 | -5,000 | -98 | 128,730 | ||||
| 2025-07-16 | 2025-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 20.0884 | -1,900 | -38 | 342,333 | ||||
| 2025-07-16 | 2025-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 800 | 3 | 344,233 | ||||
| 2025-07-16 | 2025-07-14 | 4 | Francois Cedric | APLS | Common Stock | D | 20.1864 | -137,465 | -2,775 | 343,433 | ||||
| 2025-07-16 | 2025-07-14 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 65,203 | 281 | 480,898 | ||||
| 2025-06-20 | 2025-06-18 | 4 | Chopas James George | APLS | Common Stock | D | 6,250 | 54,205 | ||||||
| 2025-06-18 | 2025-06-16 | 4 | Watson David O. | APLS | Common Stock | D | 18.7700 | -5,000 | -94 | 133,730 | ||||
| 2025-06-11 | 2025-06-09 | 4 | Boucher Kelley | APLS | Common Stock | D | 45,095 | 67,182 | ||||||
| 2025-05-29 | 2025-05-28 | 4 | Boucher Kelley | APLS | Common Stock | D | 22,087 | 22,087 | ||||||
| 2025-05-22 | 2025-05-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 12,780 | 48 | 1,160,496 | ||||
| 2025-04-21 | 2025-04-17 | 4 | WHEELER CRAIG A | APLS | Common Stock | D | 16,483 | 16,483 | ||||||
| 2025-03-18 | 2025-03-17 | 4 | Chopas James George | APLS | Common Stock | D | 24.8237 | -183 | -5 | 47,955 | ||||
| 2025-03-06 | 2025-03-05 | 4 | Watson David O. | APLS | Common Stock | D | 25.1013 | -5,569 | -140 | 138,730 | ||||
| 2025-03-06 | 2025-03-04 | 4 | Watson David O. Indirect Owner (Custodial Account for Son) | APLS | Common Stock | I | 6,667 | 10,000 | ||||||
| 2025-03-06 | 2025-03-04 | 4 | Watson David O. Indirect Owner (The Watson Education Trust) | APLS | Common Stock | I | -6,667 | 0 | ||||||
| 2025-02-12 | 2025-02-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28.5388 | -363 | -10 | 83,945 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Watson David O. | APLS | Common Stock | D | 29.5236 | -695 | -21 | 144,299 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Townsend Adam J. | APLS | Common Stock | D | 29.5236 | -695 | -21 | 84,050 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.5236 | -546 | -16 | 128,665 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.5236 | -825 | -24 | 83,664 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Lewis Karen | APLS | Common Stock | D | 29.5236 | -364 | -11 | 70,251 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 29.5236 | -278 | -8 | 55,312 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 29.5236 | -826 | -24 | 1,147,716 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Francois Cedric | APLS | Common Stock | D | 29.5236 | -2,824 | -83 | 415,695 | ||||
| 2025-01-30 | 2025-01-29 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 29.5236 | -365 | -11 | 84,308 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Watson David O. | APLS | Common Stock | D | 30.4255 | -3,323 | -101 | 144,994 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Townsend Adam J. | APLS | Common Stock | D | 30.4255 | -3,323 | -101 | 84,745 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 30.4255 | -3,088 | -94 | 129,211 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Nicholson Nur | APLS | Common Stock | D | 30.4255 | -3,948 | -120 | 84,489 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Lewis Karen | APLS | Common Stock | D | 30.4255 | -1,751 | -53 | 70,615 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Francois Cedric | APLS | Common Stock | D | 30.4255 | -13,551 | -412 | 418,519 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 30.4255 | -1,291 | -39 | 55,590 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 30.4255 | -3,948 | -120 | 1,148,542 | ||||
| 2025-01-23 | 2025-01-22 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 30.4255 | -1,396 | -42 | 84,673 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Chopas James George | APLS | Common Stock | D | 30.4255 | -1,096 | -33 | 48,138 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Watson David O. | APLS | Common Stock | D | 42,762 | 148,317 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Watson David O. | APLS | Common Stock | D | 29.9582 | -2,201 | -66 | 105,555 | ||||
| 2025-01-21 | 2025-01-17 | 4 | Townsend Adam J. | APLS | Common Stock | D | 29.9582 | -2,201 | -66 | 88,068 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 45,929 | 132,299 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.9582 | -1,730 | -52 | 86,370 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 36,426 | 88,437 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.9582 | -2,145 | -64 | 52,011 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Lewis Karen | APLS | Common Stock | D | 28,508 | 72,366 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Lewis Karen | APLS | Common Stock | D | 29.9582 | -1,241 | -37 | 43,858 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Francois Cedric | APLS | Common Stock | D | 130,662 | 432,070 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Francois Cedric | APLS | Common Stock | D | 29.9582 | -6,007 | -180 | 301,408 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 15,045 | 1,152,490 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 29.9582 | -750 | -22 | 1,137,445 | ||||
| 2025-01-21 | 2025-01-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28,508 | 86,069 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 29.9582 | -1,235 | -37 | 57,561 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Chopas James George | APLS | Common Stock | D | 12,591 | 49,234 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Chopas James George | APLS | Common Stock | D | 29.9582 | -715 | -21 | 36,643 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Baumal Caroline | APLS | Common Stock | D | 39,594 | 93,301 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Baumal Caroline | APLS | Common Stock | D | 29.9582 | -1,853 | -56 | 53,707 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Watson David O. | APLS | Common Stock | D | 28.7021 | -4,965 | -143 | 107,756 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Townsend Adam J. | APLS | Common Stock | D | 28.7021 | -2,685 | -77 | 90,269 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 28.7021 | -2,170 | -62 | 88,100 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 28.7021 | -2,632 | -76 | 54,156 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Lewis Karen | APLS | Common Stock | D | 28.7021 | -1,599 | -46 | 45,099 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Francois Cedric | APLS | Common Stock | D | 28.7021 | -6,247 | -179 | 307,415 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 28.7021 | -264 | -8 | 56,881 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 28.7021 | -2,288 | -66 | 1,138,195 | ||||
| 2025-01-14 | 2025-01-13 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28.7021 | -1,599 | -46 | 58,796 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Chopas James George | APLS | Common Stock | D | 28.7021 | -783 | -22 | 37,358 | ||||
| 2025-01-10 | 2025-01-08 | 4 | Walbert Keli | APLS | Common Stock | D | 9,090 | 9,090 | ||||||
| 2025-01-08 | 2025-01-06 | 4 | Baumal Caroline | APLS | Common Stock | D | 33.8120 | -2,816 | -95 | 55,560 | ||||
| 2025-01-03 | 2025-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 6,267 | 17,705 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 6,267 | 377,028 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 6,267 | 22,705 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 6,267 | 158,393 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 6,267 | 17,705 | ||||||
| 2025-01-03 | 2024-12-31 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 13.8500 | 10,054 | 139 | 90,270 | ||||
| 2025-01-03 | 2024-12-31 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 14.9500 | 1,042 | 16 | 80,216 | ||||
| 2024-12-27 | 2024-12-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 33.0900 | -63 | -2 | 57,145 | ||||
| 2024-12-13 | 2024-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 34.2350 | -5,000 | -171 | 112,721 | ||||
| 2024-11-01 | 2024-11-01 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | -182,146 | 472,065 | ||||||
| 2024-09-30 | 2024-09-27 | 4 | Watson David O. | APLS | Common Stock | D | 10,569 | 117,721 | ||||||
| 2024-09-30 | 2024-09-27 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | -10,569 | 70,136 | ||||||
| 2024-09-24 | 2024-09-23 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 4,600 | 61 | 152,126 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 36.7900 | -7,524 | -277 | 100,000 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 36.0900 | -29,476 | -1,064 | 107,524 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Chopas James George | APLS | Common Stock | D | 36.2060 | -192 | -7 | 38,141 | ||||
| 2024-09-04 | 2024-09-03 | 4 | Chopas James George | APLS | Common Stock | D | 39.4910 | -550 | -22 | 38,333 | ||||
| 2024-08-13 | 2024-08-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 13.8500 | 5,201 | 72 | 60,395 | ||||
| 2024-07-01 | 2024-06-28 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 900 | 12 | 134,418 | ||||
| 2024-06-21 | 2024-06-21 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 39.6300 | -1,695 | -67 | 136,998 | ||||
| 2024-06-21 | 2024-06-21 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 39.2200 | -35,305 | -1,385 | 138,693 | ||||
| 2024-05-21 | 2024-05-20 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 24,500 | 92 | 1,140,483 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.0250 | -100 | -4 | 1,115,983 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8490 | -22,472 | -963 | 1,116,083 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.1504 | -56,335 | -2,375 | 1,138,555 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 4.3100 | 78,907 | 340 | 1,194,890 | ||||
| 2024-04-19 | 2024-04-18 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 14,164 | 70,396 | ||||||
| 2024-04-19 | 2024-04-18 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -14,164 | 79,174 | ||||||
| 2024-04-15 | 2024-04-12 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 1,500 | 20 | 133,518 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.9152 | -4,728 | -260 | 1,115,983 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.1165 | -64,379 | -3,484 | 1,120,711 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 69,107 | 260 | 1,185,090 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 58.6600 | -4,000 | -235 | 93,338 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 4,000 | 40 | 97,338 | ||||
| 2024-03-20 | 2024-03-19 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 57.1790 | -18,681 | -1,068 | 173,998 | ||||
| 2024-03-19 | 2024-03-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 56.9000 | -9,913 | -564 | 54,693 | ||||
| 2024-03-18 | 2024-03-15 | 4 | Chopas James George | APLS | Common Stock | D | 56.4610 | -184 | -10 | 38,883 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 58.1335 | -3,452 | -201 | 56,287 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 57.3070 | -7,768 | -445 | 59,739 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.3500 | -100 | -6 | 1,115,983 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 62.6896 | -26,257 | -1,646 | 1,116,083 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 61.8754 | -42,750 | -2,645 | 1,142,340 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.6700 | 69,107 | 254 | 1,185,090 | ||||
| 2024-03-08 | 2024-03-06 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 3,762 | 52 | 107,152 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 65.6800 | -413 | -27 | 313,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 64.9163 | -116,512 | -7,564 | 314,075 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 64.2573 | -62,503 | -4,016 | 430,587 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 62.9631 | -41,704 | -2,626 | 493,090 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 62.2130 | -28,868 | -1,796 | 534,794 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 200,000 | 862 | 563,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 50,000 | 188 | 363,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 63.9500 | -2,000 | -128 | 93,338 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 62.8600 | -4,000 | -251 | 95,338 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 6,000 | 60 | 99,338 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Watson David O. | APLS | Common Stock | D | 67.7669 | -781 | -53 | 103,390 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Townsend Adam J. | APLS | Common Stock | D | 67.7669 | -1,148 | -78 | 92,453 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 67.7669 | -1,431 | -97 | 93,338 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Francois Cedric | APLS | Common Stock | D | 67.7669 | -3,962 | -268 | 313,662 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 67.7669 | -1,148 | -78 | 1,115,983 | ||||
| 2024-02-13 | 2024-02-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 67.7669 | -597 | -40 | 64,606 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Watson David O. | APLS | Common Stock | D | 64.1382 | -906 | -58 | 104,171 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Townsend Adam J. | APLS | Common Stock | D | 64.1382 | -906 | -58 | 93,601 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 64.1382 | -906 | -58 | 94,769 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 64.1382 | -874 | -56 | 1,117,131 | ||||
| 2024-01-31 | 2024-01-30 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 65.5300 | -971 | -64 | 57,208 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 64.1382 | -279 | -18 | 58,179 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Nicholson Nur | APLS | Common Stock | D | 64.1382 | -835 | -54 | 67,507 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Francois Cedric | APLS | Common Stock | D | 64.1382 | -2,843 | -182 | 317,624 | ||||
| 2024-01-31 | 2024-01-30 | 4 | Lewis Karen | APLS | Common Stock | D | 65.5300 | -883 | -58 | 46,387 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Lewis Karen | APLS | Common Stock | D | 64.1382 | -367 | -24 | 47,270 | ||||
| 2024-01-31 | 2024-01-29 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.1382 | -367 | -24 | 65,203 | ||||
| 2024-01-24 | 2024-01-23 | 4 | Lewis Karen | APLS | Common Stock | D | 63.6900 | -4,286 | -273 | 47,637 | ||||
| 2024-01-24 | 2024-01-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 63.6900 | -7,378 | -470 | 58,458 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Francois Cedric | APLS | Common Stock | D | 64.9960 | -13,431 | -873 | 320,467 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Watson David O. | APLS | Common Stock | D | 64.9960 | -4,184 | -272 | 105,077 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Townsend Adam J. | APLS | Common Stock | D | 64.9960 | -3,413 | -222 | 94,507 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 64.9960 | -3,551 | -231 | 95,675 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Nicholson Nur | APLS | Common Stock | D | 64.9960 | -2,593 | -169 | 68,342 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Lewis Karen | APLS | Common Stock | D | 64.9960 | -1,738 | -113 | 51,923 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 64.9960 | -1,607 | -104 | 65,836 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 64.9960 | -3,913 | -254 | 1,118,005 | ||||
| 2024-01-23 | 2024-01-22 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.9960 | -1,384 | -90 | 65,570 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Chopas James George | APLS | Common Stock | D | 64.9960 | -1,061 | -69 | 39,067 | ||||
| 2024-01-18 | 2024-01-17 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 65.5800 | -5,207 | -341 | 67,443 | ||||
| 2024-01-18 | 2024-01-17 | 4 | Lewis Karen | APLS | Common Stock | D | 65.5800 | -3,276 | -215 | 53,661 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 66.8086 | -1,632 | -109 | 1,121,918 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 6,743 | 1,123,550 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Chopas James George | APLS | Common Stock | D | 66.8086 | -864 | -58 | 40,128 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Chopas James George | APLS | Common Stock | D | 8,312 | 40,992 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Lewis Karen | APLS | Common Stock | D | 66.8086 | -1,632 | -109 | 56,937 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Lewis Karen | APLS | Common Stock | D | 16,963 | 58,569 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 66.8086 | -1,631 | -109 | 66,954 | ||||
| 2024-01-17 | 2024-01-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 16,963 | 68,585 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Nicholson Nur | APLS | Common Stock | D | 66.8086 | -1,857 | -124 | 70,935 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Nicholson Nur | APLS | Common Stock | D | 19,508 | 72,792 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Watson David O. | APLS | Common Stock | D | 66.8086 | -4,240 | -283 | 109,261 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Watson David O. | APLS | Common Stock | D | 23,748 | 113,501 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Townsend Adam J. | APLS | Common Stock | D | 66.8086 | -2,235 | -149 | 97,920 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Townsend Adam J. | APLS | Common Stock | D | 23,748 | 100,155 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 66.8086 | -2,235 | -149 | 99,226 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 23,748 | 101,461 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Baumal Caroline | APLS | Common Stock | D | 25,445 | 58,376 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 66.8086 | -7,851 | -525 | 333,898 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 72,094 | 341,749 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 66.8086 | -438 | -29 | 72,650 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 19,508 | 73,088 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Baumal Caroline | APLS | Common Stock | D | 60.0534 | -2,751 | -165 | 32,931 | ||||
| 2024-01-02 | 2024-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 3,341 | 16,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 3,341 | 11,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 3,341 | 11,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 3,341 | 132,018 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 3,341 | 370,761 | ||||||
| 2023-12-28 | 2023-12-27 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 60.2300 | -235 | -14 | 53,580 | ||||
| 2023-12-28 | 2023-12-26 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 57.8609 | -68 | -4 | 53,815 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 57.3827 | -2,300 | -132 | 89,753 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 57.0041 | -1,605 | -91 | 92,053 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 7,905 | 109 | 93,658 | ||||
| 2023-12-15 | 2023-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 6,274 | 83 | 128,677 | ||||
| 2023-12-05 | 2023-12-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0000 | -10,000 | -600 | 68,299 | ||||
| 2023-12-05 | 2023-12-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 78,299 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 61.3052 | -42,443 | -2,602 | 76,407 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 60.5019 | -67,557 | -4,087 | 118,850 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 110,000 | 1,660 | 186,407 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 61.1350 | -24,000 | -1,467 | 192,679 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 54.7866 | -300 | -16 | 77,713 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 54.7300 | -13,858 | -758 | 78,013 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 14,158 | 142 | 91,871 | ||||
| 2023-11-21 | 2023-11-21 | 4 | Francois Cedric | APLS | Common Stock | D | 48.8000 | -5,000 | -244 | 269,655 | ||||
| 2023-11-21 | 2023-10-17 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 49.0000 | -24,000 | -1,176 | 216,679 | ||||
| 2023-11-21 | 2023-11-17 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 49.9910 | -8,894 | -445 | 122,403 | ||||
| 2023-11-20 | 2023-11-17 | 4 | Machiels Alec | APLS | Common Stock | D | 47.7400 | -1,250 | -60 | 367,420 | ||||
| 2023-11-20 | 2023-11-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-11-15 | 2023-11-14 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 45,000 | 169 | 1,116,807 | ||||
| 2023-11-09 | 2023-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.2700 | -12,000 | -567 | 1,071,807 | ||||
| 2023-11-09 | 2023-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 17,494 | 47 | 1,083,807 | ||||
| 2023-10-24 | 2023-10-23 | 4 | Chopas James George | APLS | Common Stock | D | 46.0362 | -132 | -6 | 32,680 | ||||
| 2023-10-24 | 2023-10-23 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 46.0362 | -131 | -6 | 51,622 | ||||
| 2023-10-18 | 2023-10-17 | 4 | Machiels Alec | APLS | Common Stock | D | 48.5000 | -1,250 | -61 | 367,420 | ||||
| 2023-10-18 | 2023-10-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-10-10 | 2023-10-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 40.3800 | -12,000 | -485 | 1,066,313 | ||||
| 2023-10-10 | 2023-10-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,078,313 | ||||
| 2023-09-20 | 2023-09-19 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 150,000 | 804,211 | ||||||
| 2023-09-20 | 2023-09-19 | 4 | Francois Cedric | APLS | Common Stock | D | -150,000 | 274,655 | ||||||
| 2023-09-19 | 2023-09-18 | 4 | Machiels Alec | APLS | Common Stock | D | 45.0000 | -1,250 | -56 | 367,420 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 46.1470 | -10,631 | -491 | 53,284 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 42.2085 | -9,719 | -410 | 63,915 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.7600 | 9,719 | 289 | 73,634 | ||||
| 2023-09-18 | 2023-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 45.3400 | -1,250 | -57 | 367,420 | ||||
| 2023-09-18 | 2023-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-09-18 | 2023-09-14 | 4 | Chopas James George | APLS | Common Stock | D | 2,500 | 32,812 | ||||||
| 2023-09-11 | 2023-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8700 | -12,000 | -514 | 1,059,813 | ||||
| 2023-09-11 | 2023-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,071,813 | ||||
| 2023-09-07 | 2023-09-06 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 43.0100 | -1,756 | -76 | 68,299 | ||||
| 2023-09-01 | 2023-08-31 | 4 | Chopas James George | APLS | Common Stock | D | 41.2260 | -551 | -23 | 30,312 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 42.4400 | -10,284 | -436 | 424,655 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 41.7025 | -139,716 | -5,827 | 434,939 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 300,000 | 801 | 574,655 | ||||
| 2023-08-09 | 2023-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 23.6600 | -12,000 | -284 | 1,053,313 | ||||
| 2023-08-09 | 2023-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,065,313 | ||||
| 2023-07-24 | 2023-07-21 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 49,779 | 133 | 367,420 | ||||
| 2023-07-21 | 2023-07-20 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 50,000 | 134 | 317,641 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Machiels Alec | APLS | Common Stock | D | 64.7900 | -1,250 | -81 | 267,641 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-07-11 | 2023-07-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 84.5500 | -12,000 | -1,015 | 1,046,813 | ||||
| 2023-07-11 | 2023-07-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,058,813 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 91.0983 | -300 | -27 | 77,713 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 90.4165 | -3,287 | -297 | 78,013 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 89.4109 | -3,192 | -285 | 81,300 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 6,779 | 68 | 84,492 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Watson David O. | APLS | Common Stock | D | 89.9800 | -8,510 | -766 | 85,753 | ||||
| 2023-06-29 | 2023-06-28 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | 12,750 | 80,705 | ||||||
| 2023-06-29 | 2023-06-28 | 4 | Watson David O. | APLS | Common Stock | D | -12,750 | 94,263 | ||||||
| 2023-06-21 | 2023-06-20 | 4 | Machiels Alec | APLS | Common Stock | D | 88.4100 | -1,250 | -111 | 267,641 | ||||
| 2023-06-21 | 2023-06-20 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-06-09 | 2023-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 91.3500 | -12,000 | -1,096 | 1,040,313 | ||||
| 2023-06-09 | 2023-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,052,313 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 89.8259 | -30,506 | -2,740 | 77,713 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 88.3649 | -7,064 | -624 | 108,219 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 87.7886 | -30,609 | -2,687 | 115,283 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 90.6044 | -1,600 | -145 | 145,892 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 69,779 | 700 | 147,492 | ||||
| 2023-06-02 | 2023-06-01 | 4 | Lewis Karen | APLS | Common Stock | D | 86.0000 | -5,000 | -430 | 41,504 | ||||
| 2023-06-02 | 2023-06-01 | 4 | Lewis Karen | APLS | Common Stock | D | 34.1100 | 5,000 | 171 | 46,504 | ||||
| 2023-05-25 | 2023-05-24 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 20,000 | 654,211 | ||||||
| 2023-05-25 | 2023-05-24 | 4 | Francois Cedric | APLS | Common Stock | D | -20,000 | 274,655 | ||||||
| 2023-05-18 | 2023-05-17 | 4 | Machiels Alec | APLS | Common Stock | D | 88.6600 | -1,250 | -111 | 267,641 | ||||
| 2023-05-18 | 2023-05-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-05-18 | 2023-05-17 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 294,655 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 87.6739 | -2,120 | -186 | 274,655 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 87.0163 | -7,528 | -655 | 276,775 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 85.9012 | -3,007 | -258 | 284,303 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 85.0089 | -14,611 | -1,242 | 287,310 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 83.8450 | -1,800 | -151 | 301,921 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 83.1711 | -934 | -78 | 303,721 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 304,655 | ||||
| 2023-05-09 | 2023-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 92.3900 | -12,000 | -1,109 | 1,033,813 | ||||
| 2023-05-09 | 2023-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,045,813 | ||||
| 2023-05-04 | 2023-05-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 82.7100 | -5,000 | -414 | 75,995 | ||||
| 2023-05-04 | 2023-05-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-05-03 | 2023-05-03 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 20,000 | 56,232 | ||||||
| 2023-05-03 | 2023-05-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -20,000 | 77,713 | ||||||
| 2023-04-28 | 2023-04-27 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 382,946 | 382,946 | ||||||
| 2023-04-28 | 2023-04-27 | 4 | Francois Cedric | APLS | Common Stock | D | -382,946 | 274,655 | ||||||
| 2023-04-24 | 2023-04-21 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | 67,955 | 67,955 | ||||||
| 2023-04-24 | 2023-04-21 | 4 | Watson David O. | APLS | Common Stock | D | -67,955 | 107,013 | ||||||
| 2023-04-20 | 2023-04-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 657,601 | ||||
| 2023-04-20 | 2023-04-18 | 4 | Francois Cedric | APLS | Common Stock | D | 82.0240 | -30,000 | -2,461 | 637,601 | ||||
| 2023-04-20 | 2023-04-18 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 667,601 | ||||
| 2023-04-20 | 2023-04-19 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 36,232 | 36,232 | ||||||
| 2023-04-20 | 2023-04-19 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -36,232 | 97,713 | ||||||
| 2023-04-18 | 2023-04-17 | 4 | Machiels Alec | APLS | Common Stock | D | 81.0500 | -1,250 | -101 | 267,641 | ||||
| 2023-04-18 | 2023-04-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-04-11 | 2023-04-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 78.2100 | -12,000 | -939 | 1,027,313 | ||||
| 2023-04-11 | 2023-04-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,039,313 | ||||
| 2023-04-05 | 2023-04-05 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 26,990 | 634,211 | ||||||
| 2023-04-05 | 2023-04-05 | 4 | Francois Cedric | APLS | Common Stock | D | -26,990 | 637,601 | ||||||
| 2023-04-05 | 2023-04-04 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 380,000 | 607,221 | ||||||
| 2023-04-05 | 2023-04-04 | 4 | Francois Cedric | APLS | Common Stock | D | -380,000 | 664,591 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 227,221 | 227,221 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Francois Cedric | APLS | Common Stock | D | -227,221 | 1,044,591 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 74.0500 | -500 | -37 | 131,297 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Lewis Karen | APLS | Common Stock | D | 75.0000 | -5,000 | -375 | 41,430 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Lewis Karen | APLS | Common Stock | D | 34.1100 | 5,000 | 171 | 46,430 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 74.0500 | -5,000 | -370 | 75,995 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 13.8500 | 7,221 | 100 | 1,271,812 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 100,000 | 376 | 1,264,591 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 1,164,591 | ||||
| 2023-03-23 | 2023-03-21 | 4 | Francois Cedric | APLS | Common Stock | D | 62.7444 | -30,000 | -1,882 | 1,144,591 | ||||
| 2023-03-23 | 2023-03-21 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 1,174,591 | ||||
| 2023-03-21 | 2023-03-17 | 4 | Machiels Alec | APLS | Common Stock | D | 64.0300 | -1,250 | -80 | 267,641 | ||||
| 2023-03-21 | 2023-03-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-03-10 | 2023-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.7900 | -12,000 | -765 | 1,020,813 | ||||
| 2023-03-10 | 2023-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,032,813 | ||||
| 2023-03-07 | 2023-03-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 63.8400 | -5,000 | -319 | 75,995 | ||||
| 2023-03-07 | 2023-03-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-03-02 | 2023-03-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 65.3300 | -500 | -33 | 131,797 | ||||
| 2023-03-01 | 2023-02-27 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 100,000 | 376 | 1,144,591 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 68.7600 | -1,646 | -113 | 53,883 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Lewis Karen | APLS | Common Stock | D | 68.7600 | -1,104 | -76 | 41,430 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 58.5000 | -825 | -48 | 55,529 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 9,886 | 56,354 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Chopas James George | APLS | Common Stock | D | 58.5000 | -334 | -20 | 30,863 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Chopas James George | APLS | Common Stock | D | 4,044 | 31,197 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Lewis Karen | APLS | Common Stock | D | 58.5000 | -553 | -32 | 42,534 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Lewis Karen | APLS | Common Stock | D | 6,628 | 43,087 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 58.5000 | -1,195 | -70 | 1,014,313 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 9,886 | 1,015,508 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Watson David O. | APLS | Common Stock | D | 58.5000 | -825 | -48 | 174,968 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Watson David O. | APLS | Common Stock | D | 9,886 | 175,793 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 58.5000 | -715 | -42 | 69,643 | ||||
| 2023-02-22 | 2023-02-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 9,886 | 70,358 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Francois Cedric | APLS | Common Stock | D | 58.5000 | -1,602 | -94 | 1,044,591 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Francois Cedric | APLS | Common Stock | D | 13,908 | 1,046,193 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 58.5000 | -974 | -57 | 133,945 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 11,683 | 134,919 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 58.5000 | -1,041 | -61 | 75,995 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 9,886 | 77,036 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 58.5000 | -825 | -48 | 63,503 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 9,886 | 64,328 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 58.5000 | -441 | -26 | 51,341 | ||||
| 2023-02-22 | 2023-02-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 5,280 | 51,782 | ||||||
| 2023-02-21 | 2023-02-17 | 4 | Machiels Alec | APLS | Common Stock | D | 52.3800 | -1,250 | -65 | 267,641 | ||||
| 2023-02-21 | 2023-02-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 51.2100 | -532 | -27 | 165,907 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 51.2100 | -782 | -40 | 67,150 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 51.2100 | -975 | -50 | 123,236 | ||||
| 2023-02-14 | 2023-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 51.2100 | -678 | -35 | 60,472 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 51.2100 | -3,958 | -203 | 1,032,285 | ||||
| 2023-02-14 | 2023-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 51.2100 | -670 | -34 | 46,502 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 51.2100 | -1,134 | -58 | 1,005,622 | ||||
| 2023-02-10 | 2023-02-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.4500 | -12,000 | -653 | 1,006,756 | ||||
| 2023-02-10 | 2023-02-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,018,756 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 55.8500 | -5,000 | -279 | 67,932 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 72,932 | ||||
| 2023-02-02 | 2023-02-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 52.6100 | -500 | -26 | 132,297 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.7600 | -883 | -47 | 46,468 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Lewis Karen | APLS | Common Stock | D | 52.7600 | -883 | -47 | 36,459 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 52.7700 | -551 | -29 | 124,211 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Townsend Adam J. | APLS | Common Stock | D | 52.7700 | -551 | -29 | 67,932 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 52.7700 | -551 | -29 | 166,439 | ||||
| 2023-01-30 | 2023-01-27 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 52.7700 | -542 | -29 | 61,150 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Lewis Karen | APLS | Common Stock | D | 52.7700 | -367 | -19 | 37,342 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Nicholson Nur | APLS | Common Stock | D | 52.7700 | -551 | -29 | 54,442 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 52.7700 | -2,879 | -152 | 1,036,243 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.7700 | -367 | -19 | 47,351 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 52.7700 | -832 | -44 | 1,000,256 | ||||
| 2023-01-30 | 2023-01-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.7700 | -367 | -19 | 47,172 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Lewis Karen | APLS | Common Stock | D | 51.5800 | -2,955 | -152 | 37,709 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 51.5800 | -4,479 | -231 | 47,718 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Brown Victoria L. | APLS | Common Stock | D | 52.0500 | -1,412 | -73 | 23,556 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Chopas James George | APLS | Common Stock | D | 52.0500 | -919 | -48 | 27,153 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 52.0500 | -2,326 | -121 | 1,001,088 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.0500 | -2,033 | -106 | 52,197 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 52.0500 | -2,379 | -124 | 124,762 | ||||
| 2023-01-24 | 2023-01-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.0500 | -1,149 | -60 | 47,539 | ||||
| 2023-01-24 | 2023-01-20 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 52.0500 | -2,015 | -105 | 61,692 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Francois Cedric | APLS | Common Stock | D | 52.0500 | -9,453 | -492 | 1,039,122 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Lewis Karen | APLS | Common Stock | D | 52.0500 | -1,411 | -73 | 40,664 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Nicholson Nur | APLS | Common Stock | D | 52.0500 | -2,034 | -106 | 54,993 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Townsend Adam J. | APLS | Common Stock | D | 52.0500 | -1,912 | -100 | 68,483 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Watson David O. | APLS | Common Stock | D | 52.0500 | -2,034 | -106 | 166,990 | ||||
| 2023-01-19 | 2023-01-17 | 4 | Machiels Alec | APLS | Common Stock | D | 52.4200 | -1,250 | -66 | 267,641 | ||||
| 2023-01-19 | 2023-01-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-01-17 | 2023-01-12 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 27,488 | 127,141 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -3,750 | 99,653 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 22,580 | 63,707 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Francois Cedric | APLS | Common Stock | D | 83,447 | 1,048,575 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Watson David O. | APLS | Common Stock | D | 29,452 | 169,024 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Watson David O. | APLS | Common Stock | D | 24,003 | 139,572 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 19,634 | 1,003,414 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Townsend Adam J. | APLS | Common Stock | D | 27,488 | 70,395 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 19,634 | 48,688 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Nicholson Nur | APLS | Common Stock | D | 22,580 | 57,027 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Nicholson Nur | APLS | Common Stock | D | -1,875 | 33,680 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Lewis Karen | APLS | Common Stock | D | 19,634 | 42,075 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Lewis Karen | APLS | Common Stock | D | -1,250 | 22,224 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 22,580 | 54,230 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Chopas James George | APLS | Common Stock | D | 9,621 | 28,072 | ||||||
| 2023-01-10 | 2023-01-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.0800 | -12,000 | -553 | 983,780 | ||||
| 2023-01-10 | 2023-01-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 995,780 | ||||
| 2023-01-09 | 2023-01-05 | 4 | Grossi Federico | APLS | Common Stock | D | 48.7900 | -2,500 | -122 | 94,884 | ||||
| 2023-01-09 | 3 | Baumal Caroline | APLS | Common Stock | D | 133 | ||||||||
| 2023-01-05 | 2023-01-03 | 4 | Baumal Caroline | APLS | Common Stock | D | 35,549 | 35,682 | ||||||
| 2023-01-05 | 2023-01-03 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 50.7000 | -500 | -25 | 132,797 | ||||
| 2023-01-05 | 2023-01-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 50.7000 | -5,000 | -254 | 42,907 | ||||
| 2023-01-05 | 2023-01-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2023-01-05 | 3 | Baumal Caroline | APLS | Common Stock | D | 133 | ||||||||
| 2023-01-04 | 2023-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 3,867 | 267,641 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 3,867 | 8,097 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 3,867 | 133,297 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 3,867 | 8,097 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 3,867 | 13,097 | ||||||
| 2022-12-30 | 2022-12-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.6700 | 7,000 | 26 | 977,280 | ||||
| 2022-12-23 | 2022-12-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 51.6800 | -89 | -5 | 31,650 | ||||
| 2022-12-23 | 2022-04-25 | 4 | Eisele Jeffrey | APLS | Common Stock | D | -1,250 | 31,739 | ||||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 52.0697 | -24,449 | -1,273 | 965,128 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 51.9678 | -3,751 | -195 | 989,577 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 14.9500 | 6,688 | 100 | 993,328 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 15,000 | 56 | 986,640 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 28,200 | 75 | 971,640 | ||||
| 2022-12-21 | 2022-04-25 | 4 | Francois Cedric | APLS | Common Stock | D | -12,500 | 943,440 | ||||||
| 2022-12-19 | 2022-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 52.3500 | -1,250 | -65 | 263,774 | ||||
| 2022-12-19 | 2022-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-12-12 | 2022-12-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.5000 | -12,000 | -570 | 970,280 | ||||
| 2022-12-12 | 2022-12-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 982,280 | ||||
| 2022-12-07 | 2022-12-05 | 4 | Townsend Adam J. | APLS | Common Stock | D | 50.3800 | -5,000 | -252 | 42,907 | ||||
| 2022-12-07 | 2022-12-05 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | -5,000 | -75 | 47,907 | ||||
| 2022-12-02 | 2022-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 49.9300 | -2,500 | -125 | 97,384 | ||||
| 2022-12-02 | 2022-12-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 49.9300 | -500 | -25 | 129,430 | ||||
| 2022-11-17 | 2022-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 48.0100 | -1,250 | -60 | 263,774 | ||||
| 2022-11-17 | 2022-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-11-10 | 2022-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.4700 | -12,000 | -558 | 963,780 | ||||
| 2022-11-10 | 2022-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 975,780 | ||||
| 2022-11-07 | 2022-11-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 58.5400 | -5,000 | -293 | 42,907 | ||||
| 2022-11-07 | 2022-11-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | -5,000 | -75 | 47,907 | ||||
| 2022-11-03 | 2022-11-01 | 4 | Grossi Federico | APLS | Common Stock | D | 60.8300 | -2,500 | -152 | 99,884 | ||||
| 2022-11-03 | 2022-11-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 60.8300 | -500 | -30 | 129,930 | ||||
| 2022-10-28 | 2022-10-26 | 4 | Brown Victoria L. | APLS | Common Stock | D | 58.4100 | -130 | -8 | 24,844 | ||||
| 2022-10-24 | 2022-10-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 58.0000 | -196 | -11 | 29,054 | ||||
| 2022-10-24 | 2022-10-20 | 4 | Chopas James George | APLS | Common Stock | D | 58.0000 | -130 | -8 | 18,451 | ||||
| 2022-10-17 | 2022-10-14 | 4 | Machiels Alec | APLS | Common Stock | D | 59.3100 | -1,250 | -74 | 263,774 | ||||
| 2022-10-17 | 2022-10-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-10-11 | 2022-10-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 57.5000 | -12,000 | -690 | 957,280 | ||||
| 2022-10-11 | 2022-10-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 969,280 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Grossi Federico | APLS | Common Stock | D | 66.6900 | -2,500 | -167 | 102,384 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 66.6900 | -5,000 | -333 | 42,907 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-09-16 | 2022-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 66.0000 | -1,250 | -82 | 263,774 | ||||
| 2022-09-16 | 2022-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-09-12 | 2022-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.9800 | -12,000 | -768 | 950,780 | ||||
| 2022-09-12 | 2022-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 962,780 | ||||
| 2022-09-08 | 2022-09-08 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 65.0000 | -15,000 | -975 | 240,679 | ||||
| 2022-09-07 | 2022-09-06 | 4 | Townsend Adam J. | APLS | Common Stock | D | 60.3800 | -5,000 | -302 | 42,907 | ||||
| 2022-09-07 | 2022-09-06 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-09-02 | 2022-09-01 | 4 | Grossi Federico | APLS | Common Stock | D | 60.3000 | -2,500 | -151 | 104,884 | ||||
| 2022-08-31 | 2022-08-30 | 4 | Chopas James George | APLS | Common Stock | D | 58.8400 | -558 | -33 | 18,581 | ||||
| 2022-08-26 | 2022-08-25 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 4,306 | 57 | 130,430 | ||||
| 2022-08-18 | 2022-08-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 69.5000 | -5,000 | -348 | 29,250 | ||||
| 2022-08-18 | 2022-08-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-17 | 2022-08-16 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 25,394 | 356 | 126,124 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Townsend Adam J. | APLS | Common Stock | D | 69.0000 | -12,500 | -862 | 42,907 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Machiels Alec | APLS | Common Stock | D | 67.2100 | -1,250 | -84 | 263,774 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 65.6300 | -30,000 | -1,969 | 255,679 | ||||
| 2022-08-12 | 2022-08-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 67.0000 | -5,000 | -335 | 29,250 | ||||
| 2022-08-12 | 2022-08-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 67.0000 | -12,500 | -838 | 42,907 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 62.5000 | -12,000 | -750 | 944,280 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 956,280 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Townsend Adam J. | APLS | Common Stock | D | 65.0000 | -12,500 | -812 | 42,907 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-09 | 2022-08-08 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.5000 | -5,000 | -322 | 29,250 | ||||
| 2022-08-09 | 2022-08-08 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 62.0000 | -5,000 | -310 | 29,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 59.5000 | -5,000 | -298 | 34,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 10,000 | 155 | 39,250 | ||||
| 2022-08-04 | 2022-08-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 42,907 | ||||
| 2022-08-04 | 2022-08-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 56.4300 | -5,000 | -282 | 37,907 | ||||
| 2022-08-02 | 2022-08-01 | 4 | Grossi Federico | APLS | Common Stock | D | 55.9900 | -2,500 | -140 | 107,384 | ||||
| 2022-07-28 | 2022-07-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 57.0000 | -5,000 | -285 | 29,250 | ||||
| 2022-07-28 | 2022-07-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-07-22 | 2022-07-21 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 9,606 | 134 | 100,730 | ||||
| 2022-07-21 | 2022-07-19 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 56.4200 | -5,000 | -282 | 29,250 | ||||
| 2022-07-21 | 2022-07-19 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-07-18 | 2022-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 46.3300 | -1,250 | -58 | 263,774 | ||||
| 2022-07-18 | 2022-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-07-12 | 2022-07-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 48.4200 | -5,000 | -242 | 42,907 | ||||
| 2022-07-12 | 2022-07-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-07-12 | 2022-04-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | -1,875 | 42,138 | ||||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.9500 | -12,000 | -575 | 937,780 | ||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,500 | 17 | 949,780 | ||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 12,000 | 32 | 943,280 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Dunlop A. Sinclair Indirect Owner (ECM) | APLS | Common Stock | I | 46.7881 | -1,341 | -63 | 1,341 | ||||
| 2022-06-24 | 2022-06-23 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 45.0000 | -15,000 | -675 | 285,679 | ||||
| 2022-06-23 | 2022-06-22 | 4 | Watson David O. | APLS | Common Stock | D | 44.5140 | -10,000 | -445 | 115,569 | ||||
| 2022-06-22 | 2022-06-17 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 33,005 | 88 | 931,280 | ||||
| 2022-06-22 | 2022-06-17 | 4 | Brown Victoria L. | APLS | Common Stock | D | 45.0000 | -2,698 | -121 | 24,974 | ||||
| 2022-06-21 | 2022-06-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 41.7850 | -10,000 | -418 | 29,250 | ||||
| 2022-06-21 | 2022-06-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 39,250 | ||||
| 2022-06-17 | 2022-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 39.2900 | -1,250 | -49 | 263,774 | ||||
| 2022-06-17 | 2022-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,500 | 17 | 898,275 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.0900 | -12,000 | -529 | 891,775 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 12,000 | 32 | 903,775 | ||||
| 2022-06-02 | 2022-06-01 | 4 | Grossi Federico | APLS | Common Stock | D | 41.7800 | -2,500 | -104 | 109,561 | ||||
| 2022-05-31 | 2022-05-27 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 43.0000 | -10,000 | -430 | 40,358 | ||||
| 2022-05-31 | 2022-04-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-31 | 2022-04-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | -1,875 | 50,358 | ||||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 122,279 | |||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Common Stock | D | 39.1800 | -1,250 | -49 | 263,774 | ||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-05-03 | 2022-05-02 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5600 | -2,500 | -109 | 112,061 | ||||
| 2022-05-03 | 2022-04-21 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-03 | 2022-04-21 | 4 | Grossi Federico | APLS | Common Stock | D | -1,875 | 114,561 | ||||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -4,000 | 364,999 | |||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.4300 | -4,000 | -178 | 891,775 | ||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 4,000 | 11 | 895,775 | ||||
| 2022-05-02 | 2022-04-21 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-02 | 2022-04-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | -1,875 | 891,775 | ||||||
| 2022-04-27 | 2022-04-25 | 4 | Watson David O. | APLS | Common Stock | D | 50.0000 | -5,000 | -250 | 125,569 | ||||
| 2022-04-27 | 2022-04-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-04-27 | 2022-04-21 | 4 | Watson David O. | APLS | Common Stock | D | -1,875 | 130,569 | ||||||
| 2022-04-25 | 2022-04-22 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -20,000 | 35,000 | |||||
| 2022-04-25 | 2022-04-22 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 20,000 | 280 | 91,124 | ||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -7,000 | 35,000 | |||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.5300 | -7,000 | -368 | 28,481 | ||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 7,000 | 109 | 35,481 | ||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 123,529 | |||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Common Stock | D | 50.9000 | -1,250 | -64 | 263,774 | ||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -609 | 49,391 | |||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0870 | -609 | -37 | 52,233 | ||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 609 | 8 | 52,842 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -3,504 | 50,000 | |||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 57.8050 | -1,249 | -72 | 52,233 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 56.8640 | -1,437 | -82 | 53,482 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 55.8400 | -818 | -46 | 54,919 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 3,504 | 49 | 55,737 | ||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -11,496 | 53,504 | |||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 55.0500 | -11,496 | -633 | 52,233 | ||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 11,496 | 159 | 63,729 | ||||
| 2022-03-29 | 2022-03-25 | 4 | Brown Victoria L. | APLS | Common Stock | D | 49.2800 | -82 | -4 | 28,325 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Stock option (right to buy) | D | 2.67 | -1,250 | 124,779 | |||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 39.5700 | -1,250 | -49 | 259,544 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 260,794 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -7,000 | 50,723 | |||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 39.5700 | -375 | -15 | 116,436 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 7,000 | 30 | 116,811 | ||||
| 2022-03-02 | 2022-03-01 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5300 | -375 | -16 | 109,811 | ||||
| 2022-02-24 | 2022-02-23 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -4,100 | 57,723 | |||||
| 2022-02-24 | 2022-02-23 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 4,100 | 18 | 110,186 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Grossi Federico | APLS | Common Stock | D | 45.4300 | -375 | -17 | 106,086 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 126,029 | |||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Common Stock | D | 45.4300 | -1,250 | -57 | 673,774 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 675,024 | ||||
| 2022-02-15 | 2022-02-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -3,600 | 61,823 | |||||
| 2022-02-15 | 2022-02-14 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 3,600 | 16 | 106,461 | ||||
| 2022-02-15 | 2022-02-14 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -720 | 133,777 | |||||
| 2022-02-15 | 2022-02-14 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 720 | 19 | 52,233 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 47.1200 | -491 | -23 | 132,444 | ||||
| 2022-02-14 | 2022-02-11 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 46.8000 | -1,666 | -78 | 51,513 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 47.1200 | -2,523 | -119 | 955,940 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 47.1200 | -875 | -41 | 103,403 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.1200 | -1,057 | -50 | 893,650 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 47.1200 | -895 | -42 | 44,013 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -10,000 | 65,000 | |||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 50.0000 | -10,000 | -500 | 53,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 63,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 47.1200 | -678 | -32 | 53,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 47.1200 | -705 | -33 | 102,861 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Brown Victoria L. | APLS | Common Stock | D | 47.1200 | -175 | -8 | 28,407 | ||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 47.12 | 6,952 | 6,952 | |||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 4,901 | 28,481 | ||||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 47.1200 | -271 | -13 | 23,580 | ||||
| 2022-02-10 | 2021-12-08 | 5 | Watson David O. | APLS | Common Stock | D | -3,333 | 3,333 | ||||||
| 2022-02-10 | 2021-07-22 | 5 | Machiels Alec | APLS | Common Stock | D | -160,000 | 259,544 | ||||||
| 2022-02-10 | 2021-06-16 | 5 | Francois Cedric | APLS | Common Stock | D | -80,000 | 854,243 | ||||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -10,000 | 75,000 | |||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 45.0000 | -10,000 | -450 | 53,857 | ||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 63,857 | ||||
| 2022-02-07 | 2022-01-21 | 4/A | DeLong Mark Jeffrey | APLS | Stock Option (right to buy) | D | 35.46 | 19,735 | 19,735 | |||||
| 2022-02-07 | 2022-01-21 | 4/A | DeLong Mark Jeffrey | APLS | Common Stock | D | 13,913 | 24,285 | ||||||
| 2022-02-07 | 2022-01-21 | 4/A | Chopas James George | APLS | Stock Option (right to buy) | D | 35.46 | 15,116 | 15,116 | |||||
| 2022-02-07 | 2022-01-21 | 4/A | Chopas James George | APLS | Common Stock | D | 10,657 | 19,139 | ||||||
| 2022-02-02 | 2022-02-01 | 4 | Grossi Federico | APLS | Common Stock | D | 40.5800 | -375 | -15 | 103,566 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Brown Victoria L. | APLS | Common Stock | D | 38.5900 | -434 | -17 | 28,582 | ||||
| 2022-02-01 | 2022-01-28 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 38.5900 | -434 | -17 | 20,530 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 38.5900 | -650 | -25 | 103,941 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 38.5900 | -434 | -17 | 32,989 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 38.5900 | -650 | -25 | 35,555 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 38.5900 | -650 | -25 | 104,278 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 38.5900 | -650 | -25 | 132,935 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 38.5900 | -800 | -31 | 44,908 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 38.5900 | -931 | -36 | 894,707 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 38.5900 | -434 | -17 | 23,474 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 38.5900 | -2,024 | -78 | 1,338,463 | ||||
| 2022-02-01 | 2022-01-31 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 38.4700 | -1,233 | -47 | 53,857 | ||||
| 2022-02-01 | 2022-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 38.5900 | -642 | -25 | 55,090 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 35.46 | 150,672 | 150,672 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Francois Cedric | APLS | Common Stock | D | 106,244 | 1,340,487 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26,051 | 55,732 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 35.46 | 43,670 | 43,670 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 30,787 | 104,928 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 26,051 | 45,708 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 26,051 | 895,638 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Grossi Federico | APLS | Common Stock | D | 26,051 | 104,591 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 26,051 | 36,205 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 26,051 | 33,423 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Watson David O. | APLS | Common Stock | D | 26,051 | 133,585 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 35.46 | 24,774 | 24,774 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Lewis Karen | APLS | Common Stock | D | 17,466 | 23,908 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 35.46 | 24,774 | 24,774 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Brown Victoria L. | APLS | Common Stock | D | 17,466 | 29,016 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 35.46 | 15,024 | 15,024 | |||||
| 2022-01-25 | 2022-01-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 10,592 | 20,964 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Chopas James George | APLS | Stock Option (Right to Buy) | D | 35.46 | 9,892 | 9,892 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Chopas James George | APLS | Common Stock | D | 6,974 | 15,456 | ||||||
| 2022-01-24 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -3,021 | 134,497 | |||||
| 2022-01-24 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 3,021 | 81 | 29,681 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Stock Option(Right to Buy) | D | 2.67 | -1,250 | 27,279 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Common Stock | D | 40.5600 | -1,250 | -51 | 673,774 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 675,024 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -3,400 | 65,423 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 40.5600 | -375 | -15 | 78,540 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 3,400 | 15 | 78,915 | ||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -1,500 | 68,823 | |||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -3,661 | 0 | |||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 1,500 | 6 | 75,515 | ||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 3,661 | 14 | 74,015 | ||||
| 2022-01-04 | 2022-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 4,230 | 4,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 4,230 | 673,774 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 4,230 | 9,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 4,230 | 4,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 4,230 | 71,124 | ||||||
| 2022-01-04 | 2022-01-03 | 4 | Grossi Federico | APLS | Common Stock | D | 47.3100 | -375 | -18 | 70,354 | ||||
| 2021-12-28 | 2021-12-27 | 4 | Watson David O. | APLS | Common Stock | D | 48.5000 | -1,200 | -58 | 107,534 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 14.95 | -5,397 | 14,888 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 14.95 | -4,715 | 20,285 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -4,826 | 11,667 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -5,174 | 16,493 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 48.5770 | -300 | -15 | 108,734 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 47.8550 | -5,097 | -244 | 109,034 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 14.9500 | 5,397 | 81 | 114,131 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 14.9500 | 4,715 | 70 | 108,734 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 47.7160 | -5,174 | -247 | 104,019 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 4,826 | 67 | 109,193 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 5,174 | 72 | 104,367 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 47.8200 | -89 | -4 | 7,372 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Grossi Federico | APLS | Common Stock | D | 42.8800 | -375 | -16 | 70,729 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 128,529 | |||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 42.8800 | -3,000 | -129 | 669,544 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-12-09 | 2021-12-08 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -7,000 | 3,661 | |||||
| 2021-12-09 | 2021-12-08 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 7,000 | 26 | 71,104 | ||||
| 2021-12-03 | 2021-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 42.4000 | -375 | -16 | 64,104 | ||||
| 2021-11-18 | 2021-11-18 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 40.0000 | 250,000 | 10,000 | 12,806,342 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 131,529 | |||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 43.5000 | -3,000 | -130 | 669,544 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 134,529 | |||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -3,000 | -105 | 669,544 | ||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5000 | -625 | -27 | 64,479 | ||||
| 2021-11-02 | 2021-11-01 | 4 | Grossi Federico | APLS | Common Stock | D | 30.7000 | -625 | -19 | 64,805 | ||||
| 2021-10-27 | 2021-10-20 | 4 | Chopas James George | APLS | Common Stock | D | 882 | 8,482 | ||||||
| 2021-10-27 | 2021-10-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 882 | 10,372 | ||||||
| 2021-10-27 | 2021-10-26 | 4 | Brown Victoria L. | APLS | Common Stock | D | 882 | 11,422 | ||||||
| 2021-10-15 | 2021-10-14 | 4 | Grossi Federico | APLS | Common Stock | D | 34.5700 | -750 | -26 | 65,430 | ||||
| 2021-10-05 | 2021-10-01 | 4 | Grossi Federico | APLS | Common Stock | D | 33.2600 | -750 | -25 | 66,180 | ||||
| 2021-09-29 | 2021-09-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -4,000 | 10,661 | |||||
| 2021-09-29 | 2021-09-28 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 4,000 | 15 | 66,930 | ||||
| 2021-09-13 | 2021-09-10 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -6,894 | 55,000 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 6,894 | 97 | 66,894 | ||||
| 2021-09-13 | 2021-09-10 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -954 | 0 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 954 | 4 | 99,193 | ||||
| 2021-09-01 | 2021-08-30 | 4 | Chopas James George | APLS | Stock Option (right to buy) | D | 65.41 | 21,750 | 21,750 | |||||
| 2021-09-01 | 2021-08-30 | 4 | Chopas James George | APLS | Common Stock | D | 7,600 | 7,600 | ||||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 137,529 | |||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Common Stock | D | 56.9500 | -2,500 | -142 | 669,544 | ||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Grossi Federico | APLS | Common Stock | D | 63.9900 | -250 | -16 | 62,930 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 6,161 | |||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Common Stock | D | 63.9900 | -1,000 | -64 | 4,847 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -1,000 | 42,000 | |||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 65.0000 | -1,000 | -65 | 9,490 | ||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 1,000 | 16 | 10,490 | ||||
| 2021-07-22 | 2021-07-21 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 4.31 | -14,410 | 375,538 | |||||
| 2021-07-22 | 2021-07-21 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 14,410 | 62 | 1,234,243 | ||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -1,000 | 43,000 | |||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 62.3000 | -1,000 | -62 | 9,490 | ||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 1,000 | 16 | 10,490 | ||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 140,029 | |||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 62.3000 | -2,500 | -156 | 669,544 | ||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-07-15 | 2021-07-14 | 4 | Grossi Federico | APLS | Common Stock | D | 64.6800 | -500 | -32 | 63,180 | ||||
| 2021-07-09 | 2021-07-08 | 4 | Grossi Federico | APLS | Common Stock | D | 65.6800 | -250 | -16 | 63,680 | ||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 7,161 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 64.0000 | -1,000 | -64 | 4,847 | ||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -9,000 | 14,661 | |||||
| 2021-06-29 | 2021-06-28 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 9,000 | 34 | 63,930 | ||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 368,999 | |||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 65.6100 | -6,250 | -410 | 869,587 | ||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 875,837 | ||||
| 2021-06-22 | 2021-06-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 954 | |||||
| 2021-06-22 | 2021-06-21 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 98,239 | ||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 142,529 | |||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 64.8300 | -2,500 | -162 | 669,544 | ||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -4,000 | 44,000 | |||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.9575 | -4,000 | -260 | 9,490 | ||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 4,000 | 62 | 13,490 | ||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.20 | -1,000 | 34,161 | |||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Common Stock | D | 61.5550 | -1,000 | -62 | 4,847 | ||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.2000 | 1,000 | 3 | 5,847 | ||||
| 2021-06-15 | 2021-06-14 | 4 | Grossi Federico | APLS | Common Stock | D | 61.8400 | -500 | -31 | 54,930 | ||||
| 2021-06-11 | 2021-06-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0000 | -3,417 | -205 | 26,651 | ||||
| 2021-06-09 | 2021-06-08 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 10.03 | -39,880 | 358,619 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 39,880 | 400 | 74,141 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 2,682 | 303,361 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13,108 | 73,108 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | -31,855 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 8,161 | |||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 56.4000 | -1,000 | -56 | 4,847 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-06-01 | 2021-05-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 1,443 | |||||
| 2021-06-01 | 2021-05-28 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 97,750 | ||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 375,249 | |||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.4000 | -6,250 | -296 | 869,587 | ||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 875,837 | ||||
| 2021-05-20 | 2021-05-20 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 48.1000 | -5,773 | -278 | 31,855 | ||||
| 2021-05-20 | 2021-05-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.0000 | -7,612 | -381 | 300,679 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 54.0200 | -800 | -43 | 308,291 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.5000 | -10,388 | -556 | 309,091 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 52.0100 | -1,200 | -62 | 319,479 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 54.5700 | -22,318 | -1,218 | 37,628 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.7800 | -36,387 | -1,957 | 59,946 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 52.6300 | -14,216 | -748 | 96,333 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.6600 | -64,179 | -3,315 | 110,549 | ||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -2,000 | 48,000 | |||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 55.0000 | -2,000 | -110 | 9,490 | ||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 2,000 | 31 | 11,490 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Grossi Federico | APLS | Common Stock | D | 45.3900 | -500 | -23 | 55,430 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 145,029 | |||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Common Stock | D | 45.3900 | -2,500 | -113 | 669,544 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 9,161 | |||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.7300 | -1,000 | -51 | 4,847 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Grossi Federico | APLS | Common Stock | D | 50.7300 | -600 | -30 | 55,614 | ||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 10,161 | |||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -1,000 | -50 | 4,847 | ||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-04-29 | 2021-04-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -4,500 | 381,499 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 4,500 | 12 | 869,587 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 385,999 | |||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.1300 | -6,250 | -288 | 865,087 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 871,337 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -10,000 | 61,894 | |||||
| 2021-04-26 | 2021-04-23 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 10,000 | 140 | 60,000 | ||||
| 2021-04-23 | 2021-04-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 1,932 | |||||
| 2021-04-23 | 2021-04-22 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 97,261 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 147,529 | |||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Common Stock | D | 45.7600 | -2,500 | -114 | 669,544 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-04-19 | 2021-04-16 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -50,000 | 71,894 | |||||
| 2021-04-19 | 2021-04-16 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 50,000 | 700 | 50,000 | ||||
| 2021-04-15 | 2021-04-14 | 4 | Grossi Federico | APLS | Common Stock | D | 42.8200 | -500 | -21 | 56,214 | ||||
| 2021-04-09 | 3 | DeLong Mark Jeffrey | APLS | Common Stock | D | 8,698 | ||||||||
| 2021-04-05 | 2021-04-01 | 4 | Grossi Federico | APLS | Common Stock | D | 43.4100 | -600 | -26 | 56,714 | ||||
| 2021-03-29 | 2021-03-25 | 4 | Brown Victoria L. | APLS | Common Stock | D | 41.1600 | -82 | -3 | 9,952 | ||||
| 2021-03-23 | 2021-03-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -978 | 2,421 | |||||
| 2021-03-23 | 2021-03-22 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 978 | 4 | 96,772 | ||||
| 2021-03-19 | 2021-03-01 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 47.68 | 7,500 | 7,500 | |||||
| 2021-03-19 | 2021-03-01 | 4 | Brown Victoria L. | APLS | Common Stock | D | 1,250 | 10,034 | ||||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 150,029 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 46.7700 | -2,500 | -117 | 669,544 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 46.7700 | -500 | -23 | 57,314 | ||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 392,249 | |||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 50.7400 | -6,250 | -317 | 865,087 | ||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 871,337 | ||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -5,000 | 34,073 | |||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Common Stock | D | 48.6150 | -5,000 | -243 | 57,814 | ||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 5,000 | 16 | 62,814 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 47.68 | 7,500 | 7,500 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 1,250 | 7,461 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 11,161 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -2,000 | -100 | 2,347 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 4,347 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Grossi Federico | APLS | Common Stock | D | 48.5800 | -600 | -29 | 57,814 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Grossi Federico | APLS | Common Stock | D | 46.0000 | -500 | -23 | 58,414 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 152,529 | |||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Common Stock | D | 46.0000 | -2,500 | -115 | 669,544 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-02-11 | 2021-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 47.7200 | -680 | -32 | 29,290 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 47.7200 | -858 | -41 | 34,261 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Perry Nicole D | APLS | Common Stock | D | 47.7200 | -153 | -7 | 2,347 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.7200 | -688 | -33 | 865,087 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 47.7200 | -688 | -33 | 18,865 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Brown Victoria L. | APLS | Common Stock | D | 47.7200 | -144 | -7 | 8,784 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 47.7200 | -688 | -33 | 58,914 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 47.7200 | -2,523 | -120 | 1,219,833 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 47.7200 | -468 | -22 | 95,794 | ||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 13,161 | |||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -2,000 | -100 | 2,500 | ||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 4,500 | ||||
| 2021-02-04 | 2020-12-02 | 5 | Machiels Alec | APLS | Common Stock | I | 250,000 | 250,000 | ||||||
| 2021-02-04 | 2020-12-02 | 5 | Machiels Alec | APLS | Common Stock | D | -250,000 | 419,544 | ||||||
| 2021-02-04 | 2020-12-29 | 5 | Francois Cedric | APLS | Common Stock | I | 300,000 | 300,000 | ||||||
| 2021-02-04 | 2020-12-29 | 5 | Francois Cedric | APLS | Common Stock | D | -300,000 | 813,079 | ||||||
| 2021-02-02 | 2021-02-01 | 4 | Grossi Federico | APLS | Common Stock | D | 44.0000 | -600 | -26 | 59,602 | ||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 1,875 | 19,553 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 7,500 | 17,678 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 1,875 | 60,202 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 7,500 | 58,327 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 44.90 | 22,500 | 22,500 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 3,750 | 35,119 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 7,500 | 31,369 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 44.90 | 75,000 | 75,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 44.90 | 150,000 | 150,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 12,500 | 1,222,356 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 25,000 | 1,209,856 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 1,875 | 96,262 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 7,500 | 94,387 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 1,875 | 29,970 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 7,500 | 28,095 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 1,875 | 9,375 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 7,500 | 7,500 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 44.90 | 7,500 | 7,500 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 1,250 | 6,250 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 5,000 | 5,000 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Brown Victoria L. | APLS | Common Stock | D | 5,000 | 8,928 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 5,000 | 6,211 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 44.90 | 15,000 | 15,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Perry Nicole D | APLS | Common Stock | D | 2,500 | 2,500 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 1,875 | 865,775 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 7,500 | 863,900 | ||||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 4.31 | -31,992 | 389,948 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 3.76 | -39,785 | 273,840 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 31,992 | 138 | 1,184,856 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 39,785 | 150 | 1,152,864 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -20,042 | 3,399 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 3.76 | -23,441 | 0 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 20,042 | 86 | 86,887 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 3.7600 | 23,441 | 88 | 66,845 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -11,500 | 23,661 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -3,500 | 39,073 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 11,500 | 43 | 50,827 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 3,500 | 11 | 39,327 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 155,029 | |||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 53.1500 | -2,500 | -133 | 669,544 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-01-15 | 2021-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 51.9900 | -4,000 | -208 | 35,827 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Grossi Federico | APLS | Common Stock | D | 57.2400 | -600 | -34 | 39,827 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 15,161 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 57.2400 | -2,000 | -114 | 0 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 2,000 | ||||
| 2021-01-04 | 2021-01-01 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2020-12-23 | 2020-12-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 1,211 | 1,211 | ||||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 157,529 | |||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 52.1600 | -2,500 | -130 | 669,544 | ||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-12-16 | 2020-12-15 | 4 | Francois Cedric | APLS | Common Stock | D | 52.1600 | -5,000 | -261 | 1,113,079 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 56.2500 | -214 | -12 | 174,728 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 55.0100 | -17,132 | -942 | 174,942 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.8600 | -7,654 | -412 | 192,074 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -8,398 | 21,667 | |||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 55.9080 | -200 | -11 | 43,404 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 55.0010 | -900 | -50 | 43,604 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 53.8610 | -900 | -48 | 44,504 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 52.7270 | -1,163 | -61 | 45,404 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 51.3160 | -2,526 | -130 | 46,567 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 50.6070 | -2,709 | -137 | 49,093 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 8,398 | 116 | 51,802 | ||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -9,935 | 30,065 | |||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 50.0000 | -9,935 | -497 | 43,404 | ||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 9,935 | 138 | 53,339 | ||||
| 2020-12-09 | 2020-12-08 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -7,482 | 137,518 | |||||
| 2020-12-09 | 2020-12-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 7,482 | 200 | 20,595 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -18,000 | 17,161 | |||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -18,000 | -900 | 0 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 18,000 | 68 | 18,000 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -7,250 | 42,573 | |||||
| 2020-12-08 | 2020-12-04 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 7,250 | 23 | 40,427 | ||||
| 2020-12-07 | 2020-12-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.0000 | -9,470 | -483 | 199,728 | ||||
| 2020-12-07 | 2020-12-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.4100 | -9,094 | -458 | 209,198 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.0500 | -1,384 | -71 | 218,292 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.0400 | -5,052 | -253 | 219,676 | ||||
| 2020-12-02 | 2020-12-01 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 3.76 | -40,000 | 313,625 | |||||
| 2020-12-02 | 2020-12-01 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 40,000 | 150 | 1,118,079 | ||||
| 2020-12-02 | 2020-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 48.2500 | -600 | -29 | 33,177 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Francois Cedric | APLS | Common Stock | D | 39.3800 | -5,000 | -197 | 1,078,079 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -5,750 | 49,823 | |||||
| 2020-11-17 | 2020-11-16 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 5,750 | 18 | 33,777 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 160,029 | |||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Common Stock | D | 39.3800 | -2,500 | -98 | 669,544 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-11-03 | 2020-11-02 | 4 | Grossi Federico | APLS | Common Stock | D | 31.0900 | -600 | -19 | 27,725 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 162,529 | |||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -2,500 | -88 | 669,544 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 34.4600 | -5,000 | -172 | 1,083,079 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -7,500 | 165,029 | |||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -7,500 | -262 | 669,544 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 7,500 | 20 | 677,044 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 18.98 | -12,000 | 39,268 | |||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Common Stock | D | 35.0000 | -12,000 | -420 | 3,607 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Common Stock | D | 18.9800 | 12,000 | 228 | 15,607 | ||||
| 2020-10-02 | 2020-10-01 | 4 | Grossi Federico | APLS | Common Stock | D | 30.2200 | -600 | -18 | 28,325 | ||||
| 2020-09-16 | 2020-09-15 | 4 | Francois Cedric | APLS | Common Stock | D | 30.9600 | -5,000 | -155 | 1,088,079 | ||||
| 2020-09-02 | 2020-09-01 | 4 | Grossi Federico | APLS | Common Stock | D | 31.5800 | -600 | -19 | 28,925 | ||||
| 2020-08-21 | 2020-08-20 | 4 | Francois Cedric | APLS | Common Stock | D | 30.0000 | -3,457 | -104 | 1,093,079 | ||||
| 2020-08-20 | 2020-08-18 | 4 | Francois Cedric | APLS | Common Stock | D | 30.0000 | -1,543 | -46 | 1,096,536 | ||||
| 2020-08-05 | 2020-08-03 | 4 | Grossi Federico | APLS | Common Stock | D | 26.2800 | -600 | -16 | 29,525 | ||||
| 2020-07-16 | 2020-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 32.1200 | -5,000 | -161 | 1,098,079 | ||||
| 2020-07-02 | 2020-07-01 | 4 | Grossi Federico | APLS | Common Stock | D | 32.4300 | -850 | -28 | 30,125 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 172,529 | |||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.2100 | -2,500 | -76 | 669,544 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Grossi Federico | APLS | Common Stock | D | 30.2100 | -856 | -26 | 30,975 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Francois Cedric | APLS | Common Stock | D | 30.2100 | -5,000 | -151 | 1,103,079 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 175,029 | |||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Francois Cedric | APLS | Common Stock | D | 29.9200 | -5,000 | -150 | 1,108,079 | ||||
| 2020-05-12 | 2020-05-08 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 31.8068 | 5,000 | 159 | 5,000 | ||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 177,529 | |||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Francois Cedric | APLS | Common Stock | D | 29.7700 | -5,000 | -149 | 1,113,079 | ||||
| 2020-04-06 | 2020-04-02 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 26.13 | 37,500 | 37,500 | |||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 180,029 | |||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-03-18 | 2020-03-17 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 0 | |||||
| 2020-03-18 | 2020-03-17 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,083,704 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 30,637 | |||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 23.8600 | -300 | -7 | 1,053,067 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 22.2780 | -3,212 | -72 | 1,053,367 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 21.5790 | -15,065 | -325 | 1,056,579 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 20.6930 | -12,060 | -250 | 1,071,644 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 22.2860 | -700 | -16 | 1,083,704 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 21.5690 | -2,192 | -47 | 1,084,404 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 20.7280 | -2,108 | -44 | 1,086,596 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,088,704 | ||||
| 2020-03-12 | 2020-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | -161,656 | 847,025 | ||||||
| 2020-02-20 | 2020-02-19 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 61,274 | |||||
| 2020-02-20 | 2020-02-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,058,067 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 91,911 | |||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 40.6660 | -5,000 | -203 | 1,027,430 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 40.6630 | -30,637 | -1,246 | 1,032,430 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,063,067 | ||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 182,529 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Common Stock | D | 42.3500 | -2,500 | -106 | 669,544 | ||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.14 | -117,205 | 0 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 40.9790 | -55,398 | -2,270 | 1,008,681 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.1400 | 117,205 | 251 | 1,064,079 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.14 | -117,206 | 117,205 | |||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8030 | -52,075 | -2,229 | 946,874 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.1400 | 117,206 | 251 | 998,949 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 2.67 | -7,505 | 0 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 44.33 | 38,250 | 38,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 7,505 | 20 | 42,922 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 44.5000 | -5,000 | -222 | 35,417 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 6,375 | 40,417 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Grossi Federico | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 9,375 | 31,831 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Sadr Ahmad | APLS | Stock option (right to buy) | D | 44.33 | 16,350 | 16,350 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Sadr Ahmad | APLS | Common Stock | D | 2,725 | 2,725 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Lackner Thomas A. | APLS | Stock option (right to buy) | D | 44.33 | 16,350 | 16,350 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Lackner Thomas A. | APLS | Common Stock | D | 2,725 | 7,725 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Perry Nicole D | APLS | Stock option (right to buy) | D | 44.33 | 15,000 | 15,000 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Perry Nicole D | APLS | Common Stock | D | 2,500 | 2,500 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Celona Lucia | APLS | Stock option (right to buy) | D | 44.33 | 31,275 | 31,275 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Celona Lucia | APLS | Common Stock | D | 5,213 | 5,213 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Townsend Adam J. | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 9,375 | 9,375 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Francois Cedric | APLS | Stock option (right to buy) | D | 44.33 | 206,250 | 206,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 34,375 | 1,066,805 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Sullivan Timothy Eugene | APLS | Stock option (right to buy) | D | 44.33 | 70,125 | 70,125 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 11,688 | 23,387 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Deschatelets Pascal | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 9,375 | 891,118 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | SCHEIBLER LUKAS | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 9,375 | 12,310 | ||||||
| 2020-02-05 | 3/A | Machiels Alec | APLS | Common Stock | I | 1,020 | ||||||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 2.67 | -15,000 | 7,505 | |||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 15,000 | 40 | 34,042 | ||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 40.4670 | -3,000 | -121 | 19,042 | ||||
| 2020-01-21 | 2020-01-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 37.0000 | 540,540 | 20,000 | 12,556,342 | ||||
| 2020-01-21 | 2020-01-16 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 122,548 | |||||
| 2020-01-21 | 2020-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,032,430 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,638 | 153,185 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,638 | 66 | 1,001,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 41.4700 | -5,000 | -207 | 1,001,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 42.5470 | -4,562 | -194 | 1,006,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 42.1590 | -26,076 | -1,099 | 1,011,355 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 185,029 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 41.4700 | -2,500 | -104 | 669,544 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-01-03 | 2020-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2019-12-20 | 2019-12-20 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 29.5300 | -25,000 | -738 | 224,728 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 29.5100 | -31,000 | -915 | 249,728 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 28.9900 | -54,110 | -1,569 | 320,681 | ||||
| 2019-12-20 | 2019-12-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 28.5500 | -25,890 | -739 | 374,791 | ||||
| 2019-12-17 | 2019-12-16 | 4 | Francois Cedric | APLS | Common Stock | D | 27.9500 | -5,000 | -140 | 1,006,793 | ||||
| 2019-11-18 | 2019-11-15 | 4 | Francois Cedric | APLS | Common Stock | D | 27.2810 | -5,000 | -136 | 1,011,793 | ||||
| 2019-10-16 | 2019-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 26.6130 | -3,524 | -94 | 1,016,793 | ||||
| 2019-10-16 | 2019-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 25.5870 | -1,476 | -38 | 1,020,317 | ||||
| 2019-09-26 | 2019-09-25 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.6410 | -1,010 | -26 | 881,743 | ||||
| 2019-09-26 | 2019-09-25 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.2380 | -20,531 | -518 | 882,753 | ||||
| 2019-09-25 | 2019-09-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 24.9580 | -1,295 | -32 | 903,284 | ||||
| 2019-09-25 | 2019-09-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 24.5610 | -20,307 | -499 | 904,579 | ||||
| 2019-09-25 | 2019-09-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.5300 | -100 | -3 | 924,886 | ||||
| 2019-09-25 | 2019-09-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.0680 | -20,758 | -520 | 924,986 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Francois Cedric | APLS | Common Stock | D | 27.1700 | -260 | -7 | 1,021,793 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Francois Cedric | APLS | Common Stock | D | 26.5580 | -4,740 | -126 | 1,022,053 | ||||
| 2019-09-03 | 2019-08-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.7145 | 11,699 | 348 | 11,699 | ||||
| 2019-08-26 | 2019-08-23 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.67 | -37,505 | 478,200 | |||||
| 2019-08-26 | 2019-08-23 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 37,505 | 100 | 1,026,793 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -10,000 | 183,823 | |||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 27.0000 | -2,246 | -61 | 989,288 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 26.7430 | -7,754 | -207 | 991,534 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 10,000 | 21 | 999,288 | ||||
| 2019-08-09 | 2019-08-07 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 2.67 | -5,000 | 22,505 | |||||
| 2019-08-09 | 2019-08-07 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 5,000 | 13 | 22,042 | ||||
| 2019-07-01 | 2019-06-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -275,000 | 193,823 | |||||
| 2019-07-01 | 2019-06-27 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 275,000 | 588 | 989,288 | ||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-03-13 | 2019-03-11 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 17.0000 | 441,176 | 7,500 | 12,015,802 | ||||
| 2019-02-12 | 2019-02-08 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 13.85 | 40,000 | 40,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Perry Nicole D | APLS | Stock option (right to buy) | D | 13.85 | 22,000 | 22,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | SCHEIBLER LUKAS | APLS | Stock option (right to buy) | D | 13.85 | 85,000 | 85,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Francois Cedric | APLS | Stock option (right to buy) | D | 13.85 | 281,000 | 281,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Grossi Federico | APLS | Stock option (right to buy) | D | 13.85 | 85,000 | 85,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Deschatelets Pascal | APLS | Stock option (right to buy) | D | 13.85 | 95,000 | 95,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Sullivan Timothy Eugene | APLS | Stock option (right to buy) | D | 13.85 | 95,000 | 95,000 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Chan Gerald | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Machiels Alec | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Axon Steven | APLS | Stock Option (Right to Buy) | D | 2.59 | -11,500 | 348,389 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Axon Steven | APLS | Common Stock | D | 2.5900 | 11,500 | 30 | 50,110 | ||||
| 2018-11-15 | 2018-11-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -6,250 | 55,573 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 6,250 | 20 | 22,456 | ||||
| 2018-09-24 | 2018-09-21 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 19.8400 | 40,000 | 794 | 11,574,626 | ||||
| 2018-09-24 | 2018-09-20 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 19.4300 | 21,724 | 422 | 11,534,626 | ||||
| 2018-09-24 | 2018-09-20 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.7900 | 19,599 | 368 | 11,512,902 | ||||
| 2018-09-19 | 2018-09-19 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.0900 | 60,000 | 1,085 | 11,493,303 | ||||
| 2018-09-19 | 2018-09-18 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.4700 | 40,000 | 739 | 11,433,303 | ||||
| 2018-09-19 | 2018-09-17 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.8400 | 8,600 | 162 | 11,393,303 | ||||
| 2018-09-19 | 2018-09-17 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.5000 | 31,400 | 581 | 11,384,703 | ||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 2.67 | -32,818 | 27,505 | |||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Common Stock | D | 18.7840 | -15,776 | -296 | 17,042 | ||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 32,818 | 88 | 32,818 | ||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 2.67 | -624 | 60,323 | |||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Common Stock | D | -624 | 0 | ||||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 624 | 2 | 624 | ||||
| 2018-05-29 | 2018-05-24 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 20.3700 | 2,935 | 60 | 2,935 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 384,292 | 945,744 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 94,357 | 280,728 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Francois Cedric | APLS | Common Stock | D | 384,292 | 714,288 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Grossi Federico | APLS | Common Stock | D | 7,706 | 16,206 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Machiels Alec Held by spouse | APLS | Common Stock | I | 930 | 930 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Machiels Alec | APLS | Common Stock | D | 288,219 | 669,544 | ||||||
| 2018-04-17 | 3 | SCHEIBLER LUKAS | APLS | No securities are beneficially owned | D | 0 | ||||||||
| 2018-04-17 | 2018-04-13 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (right to buy) | D | 26.73 | 145,000 | 145,000 | |||||
| 2018-04-12 | 2018-04-11 | 4 | Grossi Federico | APLS | Stock Option (right to buy) | D | 3.20 | -8,500 | 61,823 | |||||
| 2018-04-12 | 2018-04-11 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 8,500 | 27 | 8,500 | ||||
| 2018-02-21 | 2018-02-20 | 4 | Axon Steven | APLS | Stock Option (right to buy) | D | 2.59 | 38,610 | 359,889 | |||||
| 2018-02-21 | 2018-02-20 | 4 | Axon Steven | APLS | Common Stock | D | 2.5900 | 38,610 | 100 | 38,610 | ||||
| 2018-02-21 | 2018-02-16 | 4 | Axon Steven | APLS | Stock Option (right to buy) | D | 14.95 | 60,000 | 60,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Francois Cedric | APLS | Stock Option (right to buy) | D | 14.95 | 280,000 | 280,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Grossi Federico | APLS | Stock Option (right to buy) | D | 14.95 | 200,000 | 200,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Perry Nicole D | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Deschatelets Pascal | APLS | Stock Option (right to buy) | D | 14.95 | 110,000 | 110,000 | |||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Series D Convertible Preferred Stock | I | 4,476,275 | 0 | ||||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Common Stock | I | 14.0000 | 1,428,571 | 20,000 | 3,527,152 | ||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Common Stock | I | 2,098,581 | 2,098,581 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Series E Convertible Preferred Stock | D | -303,916 | 0 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Series D Convertible Preferred Stock | D | -2,098,581 | 0 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Common Stock | D | 14.0000 | 1,071,428 | 15,000 | 3,473,925 | ||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Common Stock | D | 2,402,497 | 2,402,497 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series C Preferred Stock | D | -556,830 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series B Preferred Stock | D | -545,454 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series A Preferred Stock | D | -600,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Common Stock | D | 798,068 | 943,989 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series E Preferred Stock | D | -259,302 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series D Preferred Stock | D | -4,476,275 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series C Preferred Stock | D | -17,200,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series B Preferred Stock | D | -1,054,544 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 14.0000 | 575,000 | 8,050 | 11,353,303 | ||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 10,778,303 | 10,778,303 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Series E Preferred Stock | D | -648,256 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Series D Preferred Stock | D | -6,714,413 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Common Stock | D | 14.0000 | 127,515 | 1,785 | 3,579,305 | ||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Common Stock | D | 3,451,790 | 3,451,790 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Series D Preferred Stock | I | -888,969 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Series C Preferred Stock | I | -4,000,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Common Stock | I | 2,292,062 | 2,292,062 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series E Preferred Stock | I | -6,078 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series D Preferred Stock | I | -31,478 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series C Preferred Stock | I | -150,023 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series B Preferred Stock | I | -213,100 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 400,679 | 400,679 | ||||||
| 2017-11-08 | 3 | GELLERT MICHAEL E | APLS | Common Stock | D | 291,842 | ||||||||
| 2017-11-08 | 3 | GELLERT MICHAEL E | APLS | Common Stock | D | 291,842 | ||||||||
| 2017-11-08 | 3 | Dunlop A. Sinclair | APLS | Common Stock | I | 372,742 | ||||||||
| 2017-11-08 | 3 | Dunlop A. Sinclair | APLS | Common Stock | I | 372,742 | ||||||||
| 2017-11-08 | 3 | Deschatelets Pascal | APLS | Common Stock | D | 1,122,904 | ||||||||
| 2017-11-08 | 3 | Deschatelets Pascal | APLS | Common Stock | D | 1,122,904 | ||||||||
| 2017-11-08 | 3 | Watson David O. | APLS | Common Stock | I | 18,752 | ||||||||
| 2017-11-08 | 3 | Watson David O. | APLS | Common Stock | I | 18,752 | ||||||||
| 2017-11-08 | 3 | Potentia Holdings, LLC | APLS | Common Stock | D | 7,653,202 | ||||||||
| 2017-11-08 | 3 | Potentia Holdings, LLC | APLS | Common Stock | D | 7,653,202 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | I | 798,818 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | I | 798,818 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | D | 894,403 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | D | 894,403 | ||||||||
| 2017-11-08 | 3 | Machiels Alec | APLS | Common Stock | D | 762,650 | ||||||||
| 2017-11-08 | 3 | Machiels Alec | APLS | Common Stock | D | 762,650 |
P
Pasaran terbuka atau pembelian persendirian sekuriti bukan derivatif atau derivatif
S
Pasaran terbuka atau jualan persendirian sekuriti bukan derivatif atau derivatif
A
Pemberian, penganugerahan atau pemerolehan lain sekuriti daripada syarikat (seperti opsyen)
C
Penukaran derivatif
D
Penjualan atau pemindahan sekuriti kembali kepada syarikat
F
Pembayaran harga pelaksanaan atau liabiliti cukai menggunakan sebahagian daripada sekuriti yang diterima daripada syarikat
G
Hadiah sekuriti oleh atau kepada orang dalam
K
Swap ekuiti dan urus niaga lindung nilai yang serupa
M
Pelaksanaan atau penukaran sekuriti derivatif yang diterima daripada syarikat (seperti opsyen)
V
Transaksi dilaporkan secara sukarela pada Borang 4
J
Lain-lain (disertai dengan nota kaki yang menerangkan transaksi)
